MMP12 抗体 (AA 237-442)
Quick Overview for MMP12 抗体 (AA 237-442) (ABIN7600791)
抗原
See all MMP12 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 237-442
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原理
- Anti-Mmp12 Antibody Picoband®
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交叉反应 （详细）
- No cross reactivity with other proteins.
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产品特性
- Anti-Mmp12 Antibody Picoband® (ABIN7602707). Tested in WB, ELISA applications. This antibody reacts with Mouse. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
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纯化方法
- Immunogen affinity purified.
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免疫原
- E.coli-derived mouse Mmp12 recombinant protein (Position: K237-H442). Mouse Mmp12 shares 62.7% and 90.3% amino acid (aa) sequence identity with mouse and rat Mmp12, respectively.
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亚型
- IgG
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anti-Matrix Metallopeptidase 12 (Macrophage Elastase) (MMP12) (AA 20-99) antibody
MMP12 适用: 大鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Matrix Metallopeptidase 12 (Macrophage Elastase) (MMP12) (AA 100-286) antibodyMMP12 适用: 大鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Matrix Metallopeptidase 12 (Macrophage Elastase) (MMP12) (AA 391-420), (C-Term) antibodyMMP12 适用: 人, 小鼠 WB, IHC (p), IF 宿主: 兔 Polyclonal RB2026 unconjugated
anti-Matrix Metallopeptidase 12 (Macrophage Elastase) (MMP12) (AA 290-469) antibodyMMP12 适用: 人 WB, ELISA, ICC, IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Matrix Metallopeptidase 12 (Macrophage Elastase) (MMP12) (AA 294-473) antibodyMMP12 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Matrix Metallopeptidase 12 (Macrophage Elastase) (MMP12) (AA 372-463) antibodyMMP12 适用: 大鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Matrix Metallopeptidase 12 (Macrophage Elastase) (MMP12) (AA 1-470) antibodyMMP12 适用: 人 WB, IP 宿主: 兔 Polyclonal unconjugated
anti-Matrix Metallopeptidase 12 (Macrophage Elastase) (MMP12) (AA 109-470) antibodyMMP12 适用: 人 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Matrix Metallopeptidase 12 (Macrophage Elastase) (MMP12) antibodyMMP12 适用: 人 WB, ICC, IHC (p), IF 宿主: 兔 Polyclonal unconjugated
anti-Matrix Metallopeptidase 12 (Macrophage Elastase) (MMP12) (AA 201-300) antibodyMMP12 适用: 人, 小鼠 WB, ELISA, IHC (p) 宿主: 兔 Polyclonal unconjugated
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应用备注
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Western blot, 0.25-0.5 μg/mL, Mouse
ELISA, 0.1-0.5 μg/mL, -
1. Belaaouaj, A., Shipley, J. M., Kobayashi, D. K., Zimonjic, D. B., Popescu, N., Silverman, G. A., Shapiro, S. D. Human macrophage metalloelastase: genomic organization, chromosomal location, gene linkage, and tissue-specific expression. J. Biol. Chem. 270: 14568-14575, 1995. 2. Curci, J. A., Liao, S., Huffman, M. D., Shapiro, S. D., Thompson, R. W. Expression and localization of macrophage elastase (matrix metalloproteinase-12) in abdominal aortic aneurysms. J. Clin. Invest. 102: 1900-1910, 1998. 3. Hautamaki, R. D., Kobayashi, D. K., Senior, R. M., Shapiro, S. D. Requirement for macrophage elastase for cigarette smoke-induced emphysema in mice. Science 277: 2002-2004, 1997. 4. -
限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.
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储存条件
- 4 °C,-20 °C
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储存方法
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At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.
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- MMP12 (Matrix Metallopeptidase 12 (Macrophage Elastase) (MMP12))
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别名
- Mmp12
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背景
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Synonyms: 70 kDa ribosomal protein S6 kinase 1 antibody, KS6B1_HUMAN antibody, p70 alpha antibody, P70 beta 1 antibody, p70 ribosomal S6 kinase alpha antibody, p70 ribosomal S6 kinase beta 1 antibody, p70 S6 kinase alpha antibody, P70 S6 Kinase antibody, p70 S6 kinase alpha 1 antibody, p70 S6 kinase alpha 2 antibody, p70 S6K antibody, p70 S6K-alpha antibody, p70 S6KA antibody, p70(S6K) alpha antibody, p70(S6K)-alpha antibody, p70-alpha antibody, p70-S6K 1 antibody, p70-S6K antibody, P70S6K antibody, P70S6K1 antibody, p70S6Kb antibody, PS6K antibody, Ribosomal protein S6 kinase 70 kDa polypeptide 1 antibody, Ribosomal protein S6 kinase beta 1 antibody, Ribosomal protein S6 kinase beta-1 antibody, Ribosomal protein S6 kinase I antibody, RPS6KB1 antibody, S6K antibody, S6K-beta-1 antibody, S6K1 antibody, Serine/threonine kinase 14 alpha antibody, Serine/threonine-protein kinase 14A antibody, STK14A antibody
Tissue Specificity: Expressed in all tissues.
Background: Matrix metalloproteinase-12 (MMP-12) also known as macrophage metalloelastase (MME) or macrophage elastase (ME) is an enzyme that in humans is encoded by the MMP12 gene. This gene encodes a member of the matrix metalloproteinase family of extracellular matrix-degrading enzymes that are involved in tissue remodeling, wound repair, progression of atherosclerosis and tumor invasion. The encoded preproprotein undergoes proteolytic processing to generate a mature, zinc-dependent endopeptidase enzyme. Mice lacking the encoded protein have a diminished capacity to degrade extracellular matrix components, do not develop emphysema in response to long-term exposure to cigarette smoke, and exhibit impaired clearance and increased mortality upon bacterial infection. This gene is located in a cluster of other matrix metalloproteinase genes on chromosome 9. Alternate splicing generates multiple transcript variants encoding distinct isoforms.
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分子量
- 45 kDa
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基因ID
- 17381
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UniProt
- P34960
抗原
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