CD36 抗体 (AA 233-439)
Quick Overview for CD36 抗体 (AA 233-439) (ABIN7600781)
抗原
See all CD36 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 233-439
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原理
- Anti-CD36 Antibody Picoband®
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交叉反应 （详细）
- No cross-reactivity with other proteins.
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产品特性
- Anti-CD36 Antibody Picoband® (ABIN7600781). Tested in ELISA, Flow Cytometry, WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
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纯化方法
- Immunogen affinity purified.
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免疫原
- E.coli-derived human CD36 recombinant protein (Position: K233-N439).
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亚型
- IgG
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anti-CD36 (CD36) (Extracellular Domain) antibody
CD36 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-CD36 (CD36) (AA 99-114) antibodyCD36 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-CD36 (CD36) (C-Term) antibodyCD36 适用: 人 WB, IF, IHC (p), ICC 宿主: 兔 Polyclonal unconjugated
anti-CD36 (CD36) (N-Term) antibodyCD36 适用: 人, 小鼠, 大鼠, 犬, Pig, 兔, Cow, 山羊, 马, 豚鼠 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-CD36 (CD36) (AA 213-242) antibodyCD36 适用: 人 FACS, WB, IHC, IF, ELISA 宿主: 兔 Polyclonal unconjugated
anti-CD36 (CD36) (AA 51-150) antibodyCD36 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-CD36 (CD36) antibody (FITC)CD36 适用: 人 FACS 宿主: 小鼠 Monoclonal CB38 FITC
anti-CD36 (CD36) (AA 30-130) antibodyCD36 适用: 人 IHC, ELISA 宿主: 小鼠 Monoclonal 5B6F5 unconjugated
anti-CD36 (CD36) (AA 30-130) antibodyCD36 适用: 人 FACS, ELISA 宿主: 小鼠 Monoclonal 5B6B2 unconjugated
anti-CD36 (CD36) (N-Term) antibodyCD36 适用: 人, 大鼠, 犬, Pig, 兔, Cow, 山羊, 马 WB, IHC 宿主: 兔 Polyclonal unconjugated
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应用备注
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Western blot, 0.25-0.5 μg/mL, Mouse, Rat
Flow Cytometry(Fixed), 1-3 μg/1x106 cells, Human
ELISA, 0.1-0.5 μg/mL, Human
1. Tandon NN, Kralisz U, Jamieson GA (5 May 1989). "Identification of glycoprotein IV (CD36) as a primary receptor for platelet-collagen adhesion". J. Biol. Chem. 264 (13): 7576-83. PMID 2468670. 2. Jump up ^ Silverstein RL, Baird M, Lo SK, Yesner LM (15 August 1992). "Sense and antisense cDNA transfection of CD36 (glycoprotein IV) in melanoma cells. Role of CD36 as a thrombospondin receptor". J. Biol. Chem. 267 (23): 16607-12. PMID 1379600. 3. Kuda O, Pietka TA, Demianova Z, Kudova E, Cvacka J, Kopecky J, Abumrad NA (May 2013). "Sulfo-N-succinimidyl Oleate (SSO) Inhibits Fatty Acid Uptake and Signaling for Intracellular Calcium via Binding CD36 Lysine 164: SSO ALSO INHIBITS OXIDIZED LOW absorbance LIPOPROTEIN UPTAKE BY MACROPHAGES.". J. Biol. Chem. 288 (22): 15547-55. doi:10.1074/jbc.M113.473298.PMID 23603908. -
限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.
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储存条件
- 4 °C,-20 °C
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储存方法
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At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.
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- CD36
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别名
- CD36
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背景
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Synonyms: T-cell surface glycoprotein CD1c, CD1c, CD1C
Tissue Specificity: Expressed on cortical thymocytes, on certain T-cell leukemias, and in various other tissues.
Background: CD36 (cluster of differentiation 36), also known as FAT (fatty acid translocase), FAT/CD36, (FAT)/CD36, SCARB3, GP88, glycoprotein IV (gpIV), and glycoprotein IIIb (gpIIIb), is anintegral membrane protein found on the surface of many cell types in vertebrate animals. CD36 is a member of the class B scavenger receptor family of cell surface proteins. It is mapped to 7q21.11. And CD36 binds many ligands including collagen, thrombospondin, erythrocytes parasitized with Plasmodium falciparum, oxidized low absorbance lipoprotein, native lipoproteins, oxidized phospholipids, and long-chain fatty acids. In addition, CD36 function in long-chain fatty acid uptake and signaling can be irreversibly inhibited by sulfo-N-succinimidyl oleate (SSO), which binds lysine 164 within a hydrophobic pocked shared by several CD36 ligands, e.g. fatty acid and oxLDL.
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分子量
- 88 kDa
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基因ID
- 948
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UniProt
- P16671
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途径
- TLR signaling, Peptide Hormone Metabolism, Response to Growth Hormone Stimulus, Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Regulation of Lipid Metabolism by PPARalpha, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, Hepatitis C, Toll-Like Receptors Cascades, Lipid Metabolism, S100 Proteins
抗原
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