VLDLR 抗体 (AA 231-770)
Quick Overview for VLDLR 抗体 (AA 231-770) (ABIN7600777)
抗原
See all VLDLR 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 231-770
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原理
- Anti-VLDL Receptor/VLDLR Antibody Picoband®
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交叉反应 (详细)
- No cross-reactivity with other proteins.
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产品特性
- Anti-VLDL Receptor/VLDLR Antibody Picoband® (ABIN7600777). Tested in ELISA, Flow Cytometry, WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
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纯化方法
- Immunogen affinity purified.
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免疫原
- E.coli-derived human VLDL Receptor/VLDLR recombinant protein (Position: R231-S770).
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亚型
- IgG
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应用备注
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Western blot, 0.25-0.5 μg/mL, Human, Mouse, Rat
Flow Cytometry (Fixed), 1-3 μg/1x106 cells, Human
ELISA, 0.1-0.5 μg/mL, -
1. Ali, B. R., Silhavy, J. L., Gleeson, M. J., Gleeson, J. G., Al-Gazali, L. A missense founder mutation in VLDLR is associated with dysequilibrium syndrome without quadrupedal locomotion. BMC Med. Genet. 13: 80, 2012. Note: Electronic Article. 2. Boycott, K. M., Flavelle, S., Bureau, A., Glass, H. C., Fujiwara, T. M., Wirrell, E., Davey, K., Chudley, A. E., Scott, J. N., McLeod, D. R., Parboosingh, J. S. Homozygous deletion of the very low density lipoprotein receptor gene causes autosomal recessive cerebellar hypoplasia with cerebral gyral simplification. Am. J. Hum. Genet. 77: 477-483, 2005. 3. Dilber, E., Aynaci, F. M., Ahmetoglu, A. Pontocerebellar hypoplasia in two siblings with dysmorphic features. J. Child Neurol. 17: 64-66, 2002. -
限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.
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储存条件
- 4 °C,-20 °C
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储存方法
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At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.
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- VLDLR (Very Low Density Lipoprotein Receptor (VLDLR))
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别名
- VLDLR
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背景
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Synonyms: Frizzled-4, Fz-4, hFz4, FzE4, CD344, FZD4
Tissue Specificity: Almost ubiquitous. Largely expressed in adult heart, skeletal muscle, ovary, and fetal kidney. Moderate amounts in adult liver, kidney, pancreas, spleen, and fetal lung, and small amounts in placenta, adult lung, prostate, testis, colon, fetal brain and liver.
Background: The very-low-density-lipoprotein receptor (VLDLR) is a transmembrane lipoprotein receptor of the low-density-lipoprotein (LDL) receptor family. The low density lipoprotein receptor (LDLR) gene family consists of cell surface proteins involved in receptor-mediated endocytosis of specific ligands. This gene encodes a lipoprotein receptor that is a member of the LDLR family and plays important roles in VLDL-triglyceride metabolism and the reelin signaling pathway. Mutations in this gene cause VLDLR-associated cerebellar hypoplasia. Alternative splicing generates multiple transcript variants encoding distinct isoforms for this gene.
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分子量
- 100 kDa
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基因ID
- 7436
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UniProt
- P98155
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途径
- Cellular Response to Molecule of Bacterial Origin
抗原
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