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VLDLR 抗体 (AA 231-770)

This anti-VLDLR antibody is a 兔 多克隆 antibody detecting VLDLR in WB, ELISA 和 FACS. Suitable for 人, 大鼠 和 小鼠.
产品编号 ABIN7600777
发货至: 中国

Quick Overview for VLDLR 抗体 (AA 231-770) (ABIN7600777)

抗原

See all VLDLR 抗体
VLDLR (Very Low Density Lipoprotein Receptor (VLDLR))

适用

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人, 大鼠, 小鼠

宿主

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克隆类型

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多克隆

标记

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This VLDLR antibody is un-conjugated

应用范围

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Western Blotting (WB), ELISA, Flow Cytometry (FACS)
  • 抗原表位

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    AA 231-770

    原理

    Anti-VLDL Receptor/VLDLR Antibody Picoband®

    交叉反应 (详细)

    No cross-reactivity with other proteins.

    产品特性

    Anti-VLDL Receptor/VLDLR Antibody Picoband® (ABIN7600777). Tested in ELISA, Flow Cytometry, WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

    纯化方法

    Immunogen affinity purified.

    免疫原

    E.coli-derived human VLDL Receptor/VLDLR recombinant protein (Position: R231-S770).

    亚型

    IgG
  • 应用备注

    Western blot, 0.25-0.5 μg/mL, Human, Mouse, Rat
    Flow Cytometry (Fixed), 1-3 μg/1x106 cells, Human
    ELISA, 0.1-0.5 μg/mL, -
    1. Ali, B. R., Silhavy, J. L., Gleeson, M. J., Gleeson, J. G., Al-Gazali, L. A missense founder mutation in VLDLR is associated with dysequilibrium syndrome without quadrupedal locomotion. BMC Med. Genet. 13: 80, 2012. Note: Electronic Article. 2. Boycott, K. M., Flavelle, S., Bureau, A., Glass, H. C., Fujiwara, T. M., Wirrell, E., Davey, K., Chudley, A. E., Scott, J. N., McLeod, D. R., Parboosingh, J. S. Homozygous deletion of the very low density lipoprotein receptor gene causes autosomal recessive cerebellar hypoplasia with cerebral gyral simplification. Am. J. Hum. Genet. 77: 477-483, 2005. 3. Dilber, E., Aynaci, F. M., Ahmetoglu, A. Pontocerebellar hypoplasia in two siblings with dysmorphic features. J. Child Neurol. 17: 64-66, 2002.

    限制

    仅限研究用
  • 状态

    Lyophilized

    溶解方式

    Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

    浓度

    500 μg/mL

    缓冲液

    Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

    储存条件

    4 °C,-20 °C

    储存方法

    At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
    It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.
  • 抗原

    VLDLR (Very Low Density Lipoprotein Receptor (VLDLR))

    别名

    VLDLR

    背景

    Synonyms: Frizzled-4, Fz-4, hFz4, FzE4, CD344, FZD4

    Tissue Specificity: Almost ubiquitous. Largely expressed in adult heart, skeletal muscle, ovary, and fetal kidney. Moderate amounts in adult liver, kidney, pancreas, spleen, and fetal lung, and small amounts in placenta, adult lung, prostate, testis, colon, fetal brain and liver.

    Background: The very-low-density-lipoprotein receptor (VLDLR) is a transmembrane lipoprotein receptor of the low-density-lipoprotein (LDL) receptor family. The low density lipoprotein receptor (LDLR) gene family consists of cell surface proteins involved in receptor-mediated endocytosis of specific ligands. This gene encodes a lipoprotein receptor that is a member of the LDLR family and plays important roles in VLDL-triglyceride metabolism and the reelin signaling pathway. Mutations in this gene cause VLDLR-associated cerebellar hypoplasia. Alternative splicing generates multiple transcript variants encoding distinct isoforms for this gene.

    分子量

    100 kDa

    基因ID

    7436

    UniProt

    P98155

    途径

    Cellular Response to Molecule of Bacterial Origin
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