RICTOR 抗体 (AA 23-264)
Quick Overview for RICTOR 抗体 (AA 23-264) (ABIN7600744)
抗原
See all RICTOR 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 23-264
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原理
- Anti-RICTOR Antibody Picoband®
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交叉反应 （详细）
- No cross-reactivity with other proteins.
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产品特性
- Anti-RICTOR Antibody Picoband® (ABIN7600744). Tested in ELISA, Flow Cytometry, IF, IHC, ICC, WB applications. This antibody reacts with Human. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
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纯化方法
- Immunogen affinity purified.
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免疫原
- E.coli-derived human RICTOR recombinant protein (Position: E23-H264).
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亚型
- IgG
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anti-RPTOR Independent Companion of mTOR, Complex 2 (RICTOR) (AA 1-98) antibody
RICTOR 适用: 人 WB, ELISA, IHC (p), IP 宿主: 小鼠 Monoclonal 1F3 unconjugated
anti-RPTOR Independent Companion of mTOR, Complex 2 (RICTOR) antibodyRICTOR 适用: 人, 小鼠, 猴 WB, ELISA, IHC, FACS, ICC 宿主: 小鼠 Monoclonal 7B3 unconjugated
anti-RPTOR Independent Companion of mTOR, Complex 2 (RICTOR) (C-Term) antibodyRICTOR 适用: 人 WB, IHC, IHC (p), IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-RPTOR Independent Companion of mTOR, Complex 2 (RICTOR) (AA 1-245) antibodyRICTOR 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-RPTOR Independent Companion of mTOR, Complex 2 (RICTOR) antibodyRICTOR 适用: 人, 小鼠 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-RPTOR Independent Companion of mTOR, Complex 2 (RICTOR) (AA 1-99) antibodyRICTOR 适用: 人 WB, ELISA, IHC, IHC (p), IP 宿主: 小鼠 Monoclonal 1F3 unconjugated
anti-RPTOR Independent Companion of mTOR, Complex 2 (RICTOR) (AA 1-265) antibodyRICTOR 适用: 人 WB, PLA 宿主: 兔 Polyclonal unconjugated
anti-RPTOR Independent Companion of mTOR, Complex 2 (RICTOR) (AA 252-281), (N-Term) antibodyRICTOR 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal RB11675 unconjugated
anti-RPTOR Independent Companion of mTOR, Complex 2 (RICTOR) (AA 236-267) antibodyRICTOR 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-RPTOR Independent Companion of mTOR, Complex 2 (RICTOR) (AA 1617-1650) antibodyRICTOR 适用: 人, 小鼠 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
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应用备注
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Western blot, 0.25-0.5 μg/mL, Human
Immunohistochemistry (Paraffin-embedded Section), 0.5-1 μg/mL, Human
Immunocytochemistry/Immunofluorescence, 2 μg/mL, Human
Flow Cytometry (Fixed), 1-3 μg/1x106 cells, Human
ELISA, 0.1-0.5 μg/mL, -
1. Sarbassov, D. D., Ali, S. M., Kim, D.-H., Guertin, D. A., Latek, R. R., Erdjument-Bromage, H., Tempst, P., Sabatini, D. M. Rictor, a novel binding partner of mTOR, defines a rapamycin-insensitive and raptor-independent pathway that regulates the cytoskeleton. Curr. Biol. 14: 1296-1302, 2004. 2. Sarbassov, D. D., Guertin, D. A., Ali, S. M., Sabatini, D. M. Phosphorylation and regulation of Akt/PKB by the rictor-mTOR complex. Science 307: 1098-1101, 2005. 3. Shiota, C., Woo, J.-T., Lindner, J., Shelton, K. D., Magnuson, M. A. Multiallelic disruption of the rictor gene in mice reveals that mTOR complex 2 is essential for fetal growth and viability. Dev. Cell 11: 583-589, 2006. -
限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
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Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
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- RICTOR (RPTOR Independent Companion of mTOR, Complex 2 (RICTOR))
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别名
- RICTOR
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背景
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Synonyms: Rapamycin-insensitive companion of mTOR, AVO3 homolog, hAVO3, RICTOR, KIAA1999
Tissue Specificity: In fetal tissues, it is highly expressed in heart, lung liver and kidney, and weakly expressed in brain. In adult, it is highly expressed in pancreas, spleen, thymus and peripheral blood leukocytes, expressed at moderate levels in heart, placenta, lung, liver, skeletal muscle, kidney, prostate, ovary, small intestine and colon, and weakly expressed in brain and testis.
Background: Rapamycin-insensitive companion of mTOR is a protein that in human is encoded by the RICTOR gene. This gene is mapped to 5p13.1. RICTOR and MTOR are components of a protein complex that integrates nutrient- and growth factor-derived signals to regulate cell growth.
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分子量
- 230 kDa
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基因ID
- 253260
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UniProt
- Q6R327
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途径
- Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Regulation of Actin Filament Polymerization, CXCR4-mediated Signaling Events
抗原
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