RICTOR 抗体
(1 reference)-
- 抗原 See all RICTOR 抗体
- RICTOR (RPTOR Independent Companion of mTOR, Complex 2 (RICTOR))
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适用
- 人, 小鼠, 猴
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宿主
- 小鼠
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克隆类型
- 单克隆
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标记
- This RICTOR antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Flow Cytometry (FACS), Immunocytochemistry (ICC)
- 纯化方法
- purified
- 免疫原
- Purified recombinant fragment of human RICTOR expressed in E. coli.
- 克隆位点
- 7B3
- 亚型
- IgG1
- Top Product
- Discover our top product RICTOR Primary Antibody
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anti-RPTOR Independent Companion of mTOR, Complex 2 (RICTOR) (AA 1-98) antibody
RICTOR 适用: 人 WB, ELISA, IHC (p), IP 宿主: 小鼠 Monoclonal 1F3 unconjugated
anti-RPTOR Independent Companion of mTOR, Complex 2 (RICTOR) (C-Term) antibodyRICTOR 适用: 人 WB, IHC, IHC (p), IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-RPTOR Independent Companion of mTOR, Complex 2 (RICTOR) (AA 1-245) antibodyRICTOR 适用: 人 IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-RPTOR Independent Companion of mTOR, Complex 2 (RICTOR) antibodyRICTOR 适用: 人, 小鼠 IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-RPTOR Independent Companion of mTOR, Complex 2 (RICTOR) (AA 1060-1160) antibody (PerCP)RICTOR 适用: 人, 小鼠 WB, IHC 宿主: 兔 Polyclonal PerCP
anti-RPTOR Independent Companion of mTOR, Complex 2 (RICTOR) (AA 1060-1160) antibody (APC)RICTOR 适用: 人, 小鼠 WB, IHC 宿主: 兔 Polyclonal APC
anti-RPTOR Independent Companion of mTOR, Complex 2 (RICTOR) (AA 1060-1160) antibody (Atto 594)RICTOR 适用: 人, 小鼠 WB, IHC 宿主: 兔 Polyclonal Atto 594
anti-RPTOR Independent Companion of mTOR, Complex 2 (RICTOR) (AA 1060-1160) antibody (Atto 488)RICTOR 适用: 人, 小鼠 WB, IHC 宿主: 兔 Polyclonal Atto 488
anti-RPTOR Independent Companion of mTOR, Complex 2 (RICTOR) (AA 1060-1160) antibody (Atto 390)RICTOR 适用: 人, 小鼠 WB, IHC 宿主: 兔 Polyclonal Atto 390
anti-RPTOR Independent Companion of mTOR, Complex 2 (RICTOR) (AA 1-265) antibodyRICTOR 适用: 人 WB, PLA 宿主: 兔 Polyclonal unconjugated
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- 应用备注
- ELISA: 1:10000, WB: 1:500 - 1:2000, IHC: 1:200 - 1:1000, ICC: 1:200 - 1:1000, FCM: 1:200 - 1:400
- 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
- Ascitic fluid containing 0.03 % sodium azide.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- 4 °C/-20 °C
- 储存方法
- 4°C, -20°C for long term storage
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: "Identification of Sin1 as an essential TORC2 component required for complex formation and kinase activity." in: Genes & development, Vol. 20, Issue 20, pp. 2820-32, (2006) (PubMed).
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: "Identification of Sin1 as an essential TORC2 component required for complex formation and kinase activity." in: Genes & development, Vol. 20, Issue 20, pp. 2820-32, (2006) (PubMed).
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- 抗原
- RICTOR (RPTOR Independent Companion of mTOR, Complex 2 (RICTOR))
- 别名
- RICTOR (RICTOR 产品)
- 别名
- PIA antibody, mAVO3 antibody, 4921505C17Rik antibody, 6030405M08Rik antibody, AVO3 antibody, AW492497 antibody, D530039E11Rik antibody, Fyb antibody, RPTOR independent companion of MTOR complex 2 antibody, RPTOR independent companion of MTOR, complex 2 antibody, RICTOR antibody, Rictor antibody
- 背景
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Description: Cell growth is a fundamental biological process whereby cells accumulate mass and increase in size. The mammalian TOR (mTOR) pathway regulates growth by coordinating energy and nutrient signals with growth factor-derived signals . mTOR is a large protein kinase with two different complexes. One complex contains mTOR, GβL and raptor, which is a target of rapamycin. The other complex, insensitive to rapamycin, includes mTOR, GβL, Sin1 and rictor . The mTOR-rictor complex phosphorylates Ser473 of Akt/PKB in vitro . This phosphorylation is essential for full Akt/PKB activation. Furthermore, an siRNA knockdown of rictor inhibits Ser473 phosphorylation in 3T3-L1 adipocytes . This complex has also been shown to phosphorylate the rapamycin-resistant mutants of S6K1, another effector of mTOR .
Aliases: PIA, mAVO3, KIAA1999, MGC39830, DKFZp686B11164, RICTOR
- 分子量
- 192 kDa
- 基因ID
- 253260
- HGNC
- 253260
- 途径
- Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Regulation of Actin Filament Polymerization, CXCR4-mediated Signaling Events
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