DEPTOR 抗体 (AA 22-409)
Quick Overview for DEPTOR 抗体 (AA 22-409) (ABIN7600694)
抗原
See all DEPTOR 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 22-409
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原理
- Anti-DEPDC6/DEPTOR Antibody Picoband®
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交叉反应 （详细）
- No cross-reactivity with other proteins
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产品特性
- Anti-DEPDC6-DEPTOR Antibody Picoband® (ABIN7600694). Tested in WB, IHC, Flow Cytometry, ELISA applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
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纯化方法
- Immunogen affinity purified.
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免疫原
- E.coli-derived human DEPDC6/DEPTOR recombinant protein (Position: A22-C409). Human DEPDC6/DEPTOR shares 97.9% amino acid (aa) sequence identity with mouse DEPDC6/DEPTOR.
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亚型
- IgG
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anti-DEP Domain Containing mTOR-Interacting Protein (DEPTOR) (AA 56-170) antibody
DEPTOR 适用: 人, 小鼠, 大鼠 WB, IF (cc), IF (p), ELISA, IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-DEP Domain Containing mTOR-Interacting Protein (DEPTOR) (AA 1-409) antibodyDEPTOR 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-DEP Domain Containing mTOR-Interacting Protein (DEPTOR) (AA 1-220) antibodyDEPTOR 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-DEP Domain Containing mTOR-Interacting Protein (DEPTOR) (AA 86-120) antibodyDEPTOR 适用: 人 WB 宿主: 兔 Polyclonal RB57442 unconjugated
anti-DEP Domain Containing mTOR-Interacting Protein (DEPTOR) (AA 3-38) antibodyDEPTOR 适用: 人 WB 宿主: 兔 Polyclonal RB57441 unconjugated
anti-DEP Domain Containing mTOR-Interacting Protein (DEPTOR) (AA 1-409) antibodyDEPTOR 适用: 人 WB, ELISA 宿主: 小鼠 Polyclonal unconjugated
anti-DEP Domain Containing mTOR-Interacting Protein (DEPTOR) (AA 1-409) antibodyDEPTOR 适用: 人 ELISA 宿主: 小鼠 Monoclonal 5B3 unconjugated
anti-DEP Domain Containing mTOR-Interacting Protein (DEPTOR) (AA 230-280) antibodyDEPTOR 适用: 人, 大鼠, 马, 猴 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
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Western blot, 0.25-0.5 μg/mL, Human, Mouse, Rat
Immunohistochemistry, 2-5 μg/mL, Human
Flow Cytometry (Fixed), 1-3 μg/1x106 cells, Human
ELISA, 0.1-0.5 μg/mL
1. Hartz, P. A. Personal Communication. Baltimore, Md. 8/20/2009. 2. Peterson, T. R., Laplante, M., Thoreen, C. C., Sancak, Y., Kang, S. A., Kuehl, W. M., Gray, N. S., Sabatini, D. M. DEPTOR is an mTOR inhibitor frequently overexpressed in multiple myeloma cells and required for their survival. Cell 137: 873-886, 2009. -
限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.
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储存条件
- 4 °C,-20 °C
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储存方法
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At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.
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- DEPTOR (DEP Domain Containing mTOR-Interacting Protein (DEPTOR))
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别名
- DEPTOR
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背景
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Synonyms: DEPTOR, DEPDC6, DEP domain-containing mTOR-interacting protein, DEP domain-containing protein 6
Background: DEP domain-containing mTOR-interacting protein (DEPTOR) also known as DEP domain-containing protein 6 (DEPDC6) is a protein that in humans is encoded by the DEPTOR gene. Enables phosphatidic acid binding activity and protein serine/threonine kinase inhibitor activity. Involved in several processes, including negative regulation of TOR signaling, negative regulation of cell size, and negative regulation of protein kinase activity. Is active in lysosomal membrane.
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分子量
- 48 kDa
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基因ID
- 64798
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途径
- PI3K-Akt Signaling, RTK signaling, Regulation of Cell Size, BCR Signaling, Warburg Effect
抗原
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