RAD51 Homolog B 抗体 (AA 22-384)
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- 抗原 See all RAD51 Homolog B (Rad51B) 抗体
- RAD51 Homolog B (Rad51B)
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抗原表位
- AA 22-384
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This RAD51 Homolog B antibody is un-conjugated
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应用范围
- Western Blotting (WB), ELISA, Immunofluorescence (IF), Flow Cytometry (FACS), Immunocytochemistry (ICC)
- 原理
- Anti-RAD51L1/RAD51B Antibody Picoband®
- 交叉反应 （详细）
- No cross-reactivity with other proteins
- 产品特性
- Anti-RAD51L1/RAD51B Antibody Picoband® (ABIN7600692). Tested in WB, ICC/IF, Flow Cytometry, ELISA applications. This antibody reacts with Human. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
- 纯化方法
- Immunogen affinity purified.
- 免疫原
- E.coli-derived human RAD51L1/RAD51B recombinant protein (Position: H22-F384). Human RAD51L1/RAD51B shares 85.8% amino acid (aa) sequence identity with mouse RAD51L1/RAD51B.
- 亚型
- IgG
- Top Product
- Discover our top product Rad51B Primary Antibody
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anti-RAD51 Homolog B (Rad51B) antibody
Rad51B 适用: 人, 小鼠, 猴 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-RAD51 Homolog B (Rad51B) (Middle Region) antibodyRad51B 适用: 人, 小鼠, 大鼠, Cow, 犬, 豚鼠, 兔, 马 WB 宿主: 兔 Polyclonal unconjugated
anti-RAD51 Homolog B (Rad51B) (AA 1-384) antibodyRad51B 适用: 人 WB, IF 宿主: 小鼠 Polyclonal unconjugated
anti-RAD51 Homolog B (Rad51B) (AA 1-384) antibodyRad51B 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-RAD51 Homolog B (Rad51B) (Center) antibodyRad51B 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
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- 应用备注
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Western blot, 0.25-0.5 μg/mL, Human
Immunocytochemistry/Immunofluorescence, 5 μg/mL, Human
Flow Cytometry (Fixed), 1-3 μg/1x106 cells, Human
ELISA, 0.1-0.5 μg/mL
1. Adelman, C. A., Lolo, R. L., Birkbak, N. J., Murina, O., Matsuzaki, K., Horejsi, Z., Parmar, K., Borel, V., Skehel, J. M., Stamp, G., D'Andrea, A., Sartori, A. A., Swanton, C., Boulton, S. J. HELQ promotes RAD51 paralogue-dependent repair to avert germ cell loss and tumorigenesis. Nature 502: 381-384, 2013. 2. Albala, J. S., Thelen, M. P., Prange, C., Fan, W., Christensen, M., Thompson, L. H., Lennon, G. G. Identification of a novel human RAD51 homolog, RAD51B. Genomics 46: 476-479, 1997. Note: Erratum: Genomics 51: 480 only, 1998. 3. Cartwright, R., Dunn, A. M., Simpson, P. J., Tambini, C. E., Thacker, J. Isolation of novel human and mouse genes of the recA/RAD51 recombination-repair gene family. Nucleic Acids Res. 26: 1653-1659, 1998. - 限制
- 仅限研究用
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- 状态
- Lyophilized
- 溶解方式
- Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
- 浓度
- 500 μg/mL
- 缓冲液
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.
- 储存条件
- 4 °C,-20 °C
- 储存方法
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At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.
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- 抗原
- RAD51 Homolog B (Rad51B)
- 别名
- RAD51B (Rad51B 产品)
- 背景
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Synonyms: RAD51B, RAD51L1, REC2, DNA repair protein RAD51 homolog 2, R51H2, RAD51 homolog B, Rad51B, RAD51-like protein 1
Background: The protein encoded by this gene is a member of the RAD51 protein family. RAD51 family members are evolutionarily conserved proteins essential for DNA repair by homologous recombination. This protein has been shown to form a stable heterodimer with the family member RAD51C, which further interacts with the other family members, such as RAD51, XRCC2, and XRCC3. Overexpression of this gene was found to cause cell cycle G1 delay and cell apoptosis, which suggested a role of this protein in sensing DNA damage. Rearrangements between this locus and high mobility group AT-hook 2 (HMGA2, GeneID 8091) have been observed in uterine leiomyomata.
- 分子量
- 42 kDa
- 基因ID
- 5890
- UniProt
- O15315
- 途径
- DNA Damage Repair
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