JAG2 抗体 (AA 22-1153)
Quick Overview for JAG2 抗体 (AA 22-1153) (ABIN7600669)
抗原
See all JAG2 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 22-1153
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原理
- Anti-Jagged 2/JAG2 Antibody Picoband®
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交叉反应 （详细）
- No cross reactivity with other proteins.
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产品特性
- Anti-Jagged 2/JAG2 Antibody Picoband® (ABIN7600669). Tested in ELISA, WB applications. This antibody reacts with Human. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
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纯化方法
- Immunogen affinity purified.
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免疫原
- E.coli-derived human Jagged 2/JAG2 recombinant protein (Position: Q22-N1153). Human JAG2 shares 91.1% and 91% amino acid (aa) sequence identity with mouse and rat JAG2, respectively.
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亚型
- IgG
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anti-Jagged 2 (JAG2) (AA 714-981) antibody
JAG2 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Jagged 2 (JAG2) (AA 709-941) antibodyJAG2 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Jagged 2 (JAG2) (AA 121-210) antibodyJAG2 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 1C5 unconjugated
anti-Jagged 2 (JAG2) (AA 24-200) antibodyJAG2 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-Jagged 2 (JAG2) antibodyJAG2 适用: 人, 小鼠, 大鼠 FACS, IHC (fro) 宿主: 仓鼠 Monoclonal HMJ2-1 unconjugated
anti-Jagged 2 (JAG2) antibodyJAG2 适用: 人, 小鼠, 大鼠 IF 宿主: 兔 Polyclonal unconjugated
anti-Jagged 2 (JAG2) (AA 121-210) antibodyJAG2 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 4C8 unconjugated
anti-Jagged 2 (JAG2) (N-Term) antibodyJAG2 适用: 人, 小鼠, 大鼠, Pig WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Jagged 2 (JAG2) (AA 1209-1238), (C-Term) antibodyJAG2 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal RB1913-1914 unconjugated
anti-Jagged 2 (JAG2) (AA 150-200) antibodyJAG2 适用: 人, 猴 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
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Western blot, 0.25-0.5 μg/mL, Human
ELISA, 0.1-0.5 μg/mL, -
1. Asnaghi, L., Handa, J. T., Merbs, S. L., Harbour, J. W., Eberhart, C. G. A role for Jag2 in promoting uveal melanoma dissemination and growth. Invest. Ophthal. Vis. Sci. 54: 295-306, 2013. 2. Deng Y, Madan A, Banta AB, Friedman C, Trask BJ, Hood L, Li L (April 2000). "Characterization, chromosomal localization, and the complete 30-kb DNA sequence of the human Jagged2 (JAG2) gene". Genomics 63 (1): 133-8. 3. Ikeuchi, T., Sisodia, S. S. The Notch ligands, Delta1 and Jagged2, are substrates for presenilin-dependent 'gamma-secretase' cleavage. J. Biol. Chem. 278: 7751-7754, 2003. 4. Luo B, Aster JC, Hasserjian RP, Kuo F, Sklar J (October 1997). "Isolation and functional analysis of a cDNA for human Jagged2, a gene encoding a ligand for the Notch1 receptor". Mol Cell Biol 17 (10): 6057-67. -
限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.
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储存条件
- 4 °C,-20 °C
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储存方法
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At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.
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- JAG2 (Jagged 2 (JAG2))
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别名
- JAG2
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背景
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Synonyms: 70 kDa ribosomal protein S6 kinase 1 antibody, KS6B1_HUMAN antibody, p70 alpha antibody, P70 beta 1 antibody, p70 ribosomal S6 kinase alpha antibody, p70 ribosomal S6 kinase beta 1 antibody, p70 S6 kinase alpha antibody, P70 S6 Kinase antibody, p70 S6 kinase alpha 1 antibody, p70 S6 kinase alpha 2 antibody, p70 S6K antibody, p70 S6K-alpha antibody, p70 S6KA antibody, p70(S6K) alpha antibody, p70(S6K)-alpha antibody, p70-alpha antibody, p70-S6K 1 antibody, p70-S6K antibody, P70S6K antibody, P70S6K1 antibody, p70S6Kb antibody, PS6K antibody, Ribosomal protein S6 kinase 70 kDa polypeptide 1 antibody, Ribosomal protein S6 kinase beta 1 antibody, Ribosomal protein S6 kinase beta-1 antibody, Ribosomal protein S6 kinase I antibody, RPS6KB1 antibody, S6K antibody, S6K-beta-1 antibody, S6K1 antibody, Serine/threonine kinase 14 alpha antibody, Serine/threonine-protein kinase 14A antibody, STK14A antibody
Tissue Specificity: Expressed in all tissues.
Background: Protein jagged-2, also known as SER2, is a protein that in humans is encoded by the JAG2 gene. It is mapped to 14q32.33. The protein encoded by this gene is one of several ligands that activate Notch and related receptors. Notch ligands Delta1 and JAG2 are subject to presenilin-dependent, intramembranous gamma-secretase processing, resulting in the production of soluble intracellular derivatives. JAG2 can promote the growth and dissemination of uveal melanoma cells.
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分子量
- 130 kDa
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基因ID
- 3714
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UniProt
- Q9Y219
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途径
- Notch Signaling, Sensory Perception of Sound
抗原
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