电话:
+86 (0512) 65829739
传真:
+86 (010) 6788 5057
电子邮件:
orders@antibodies-online.cn

OAT 抗体 (AA 214-439)

This anti-OAT antibody is a 兔 多克隆 antibody detecting OAT in WB, ELISA, IHC 和 FACS. Suitable for 人, 小鼠 和 大鼠.
产品编号 ABIN7600649
发货至: 中国

Quick Overview for OAT 抗体 (AA 214-439) (ABIN7600649)

抗原

See all OAT 抗体
OAT (Ornithine Aminotransferase (OAT))

适用

  • 47
  • 20
  • 19
  • 4
  • 4
  • 4
  • 3
  • 3
  • 3
  • 2
  • 1
  • 1
  • 1
  • 1
人, 小鼠, 大鼠

宿主

  • 43
  • 4

克隆类型

  • 43
  • 4
多克隆

标记

  • 28
  • 3
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
This OAT antibody is un-conjugated

应用范围

  • 33
  • 14
  • 10
  • 7
  • 7
  • 6
  • 3
  • 3
  • 2
  • 1
Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Flow Cytometry (FACS)
  • 抗原表位

    • 8
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 214-439

    原理

    Anti-ornithine aminotransferase/OAT Antibody Picoband®

    交叉反应 (详细)

    No cross-reactivity with other proteins.

    产品特性

    Anti-ornithine aminotransferase/OAT Antibody Picoband® (ABIN7600649). Tested in ELISA, Flow Cytometry, IHC, WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

    纯化方法

    Immunogen affinity purified.

    免疫原

    E.coli-derived human OAT recombinant protein (Position: A214-F439).

    亚型

    IgG
  • 应用备注

    Western blot, 0.1-0.25 μg/mL, Human, Mouse, Rat
    Immunohistochemistry (Paraffin-embedded Section), 2-5 μg/mL, Human
    Flow Cytometry (Fixed), 1-3 μg/1x106 cells, Human
    ELISA, 0.1-0.5 μg/mL, -
    1. Akaki, Y., Hotta, Y., Mashima, Y., Murakami, A., Kennaway, N. G., Weleber, R. G., Inana, G. A deletion in the ornithine aminotransferase gene in gyrate atrophy. J. Biol. Chem. 267: 12950-12954, 1992. 2. Barrett, D. J., Bateman, J. B., Sparkes, R. S., Mohandas, T., Klisak, I., Inana, G. Chromosomal localization of human ornithine aminotransferase gene sequences to 10q26 and Xp11.2. Invest. Ophthal. Vis. Sci. 28: 1037-1042, 1987. 3. Bisaillon, J. J., Radden, L. A., II, Szabo, E. T., Hughes, S. R., Feliciano, A. M., Nesta, A. V., Petrovic, B., Palanza, K. M., Lancinskas, D., Szmurlo, T. A., Artus, D. C., Kapper, M. A., Mulrooney, J. P., King, T. R. The retarded hair growth (rhg) mutation in mice is an allele of ornithine aminotransferase (Oat). Molec. Genet. Metab. Rep. 1: 378-390, 2014.

    限制

    仅限研究用
  • 状态

    Lyophilized

    溶解方式

    Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

    浓度

    500 μg/mL

    缓冲液

    Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

    储存条件

    4 °C,-20 °C

    储存方法

    Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
    It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
  • 抗原

    OAT (Ornithine Aminotransferase (OAT))

    别名

    OAT

    背景

    Synonyms: Podoplanin, Aggrus, Glycoprotein 36, Gp36, PA2.26 antigen, T1-alpha, T1A, 29 kDa cytosolic podoplanin intracellular domain, PICD, PDPN, GP36, PSEC0003, PSEC0025

    Tissue Specificity: Highly expressed in placenta, lung, skeletal muscle and brain. Weakly expressed in brain, kidney and liver. In placenta, expressed on the apical plasma membrane of endothelium. In lung, expressed in alveolar epithelium. Up-regulated in colorectal tumors and expressed in 25 % of early oral squamous cell carcinomas.

    Background: Ornithine aminotransferase (OAT) is an enzyme which is encoded in human by the OAT gene located on chromosome 10. This gene encodes the mitochondrial enzyme ornithine aminotransferase, which is a key enzyme in the pathway that converts arginine and ornithine into the major excitatory and inhibitory neurotransmitters glutamate and GABA. Mutations that result in a deficiency of this enzyme cause the autosomal recessive eye disease Gyrate Atrophy. Alternatively spliced transcript variants encoding different isoforms have been described. Related pseudogenes have been defined on the X chromosome.

    分子量

    49 kDa

    基因ID

    4942

    UniProt

    P04181
You are here:
Chat with us!