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PLA2R1 抗体 (AA 21-66)

PLA2R1 适用: 人 WB, ELISA 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN7600628
发货至: 中国
  • 抗原 See all PLA2R1 抗体
    PLA2R1 (phospholipase A2 Receptor 1, 180kDa (PLA2R1))
    抗原表位
    • 5
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 21-66
    适用
    • 12
    • 3
    宿主
    • 12
    • 1
    • 1
    克隆类型
    • 13
    • 1
    多克隆
    标记
    • 9
    • 3
    • 1
    • 1
    This PLA2R1 antibody is un-conjugated
    应用范围
    • 8
    • 7
    • 5
    • 3
    • 3
    • 1
    • 1
    • 1
    Western Blotting (WB), ELISA
    原理
    Anti-PLA2R/PLA2R1 Antibody Picoband®
    交叉反应 (详细)
    No cross-reactivity with other proteins.
    产品特性
    Anti-PLA2R/PLA2R1 Antibody Picoband® (ABIN7600628). Tested in ELISA, WB applications. This antibody reacts with Human. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
    纯化方法
    Immunogen affinity purified.
    免疫原
    E.coli-derived human PLA2R/PLA2R1 recombinant protein (Position: E21-Q66).
    亚型
    IgG
    Top Product
    Discover our top product PLA2R1 Primary Antibody
  • 应用备注
    Western blot, 0.25-0.5 μg/mL, Human
    ELISA, 0.1-0.5 μg/mL, -
    1. Ancian, P., Lambeau, G., Mattei, M.-G., Lazdunski, M. The human 180- kDa receptor for secretory phospholipases A2: molecular cloning, identification of a secreted soluble form, expression, and chromosomal localization. J. Biol. Chem. 270: 8963-8970, 1995. 2. Beck, L. H., Jr., Bonegio, R. G. B., Lambeau, G., Beck, D. M., Powell, D. W., Cummins, T. D., Klein, J. B., Salant, D. J. M-type phospholipase A2 receptor as target antigen in idiopathic membranous nephropathy. New Eng. J. Med. 361: 11-21, 2009. 3. Debiec, H., Ronco, P. PLA2R autoantibodies and PLA2R glomerular deposits in membranous nephropathy. (Letter) New Eng. J. Med. 364: 689-690, 2011.
    限制
    仅限研究用
  • 状态
    Lyophilized
    溶解方式
    Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
    浓度
    500 μg/mL
    缓冲液
    Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.
    储存条件
    4 °C,-20 °C
    储存方法
    At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
    It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.
  • 抗原
    PLA2R1 (phospholipase A2 Receptor 1, 180kDa (PLA2R1))
    别名
    PLA2R1 (PLA2R1 产品)
    背景

    Synonyms: Interleukin-25, IL-25, Interleukin-17E, IL-17E, IL25, IL17E, UNQ3120/PRO10272

    Tissue Specificity: Expressed at low levels in several tissues, including brain, kidney, lung, prostate, testis, spinal cord, adrenal gland, and trachea.

    Background: Secretory phospholipase A2 receptor is an enzyme that in humans is encoded by the PLA2R1 gene. This gene represents a phospholipase A2 receptor. The encoded protein likely exists as both a transmembrane form and a soluble form. The transmembrane receptor may play a role in clearance of phospholipase A2, thereby inhibiting its action. Polymorphisms at this locus have been associated with susceptibility to idiopathic membranous nephropathy. Alternatively spliced transcript variants encoding different isoforms have been identified.

    分子量
    169 kDa
    基因ID
    22925
    UniProt
    Q13018
    途径
    Positive Regulation of Response to DNA Damage Stimulus
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