PLA2R1 抗体 (AA 21-66)
Quick Overview for PLA2R1 抗体 (AA 21-66) (ABIN7600628)
抗原
See all PLA2R1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 21-66
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原理
- Anti-PLA2R/PLA2R1 Antibody Picoband®
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交叉反应 （详细）
- No cross-reactivity with other proteins.
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产品特性
- Anti-PLA2R/PLA2R1 Antibody Picoband® (ABIN7600628). Tested in ELISA, WB applications. This antibody reacts with Human. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
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纯化方法
- Immunogen affinity purified.
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免疫原
- E.coli-derived human PLA2R/PLA2R1 recombinant protein (Position: E21-Q66).
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亚型
- IgG
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anti-phospholipase A2 Receptor 1, 180kDa (PLA2R1) (AA 1418-1487) antibody
PLA2R1 适用: 小鼠 WB, IHC, ICC, IP 宿主: 兔 Polyclonal unconjugated
anti-phospholipase A2 Receptor 1, 180kDa (PLA2R1) (AA 385-643) antibodyPLA2R1 适用: 人 WB, IHC, ICC, IP 宿主: 兔 Polyclonal unconjugated
anti-phospholipase A2 Receptor 1, 180kDa (PLA2R1) (Internal Region) antibodyVerified PLA2R1 适用: 人 ELISA, FACS 宿主: 山羊 Polyclonal unconjugated
anti-phospholipase A2 Receptor 1, 180kDa (PLA2R1) (AA 385-643) antibodyPLA2R1 适用: 人 WB, IHC, ICC, IP 宿主: 小鼠 Monoclonal C6 unconjugated
anti-phospholipase A2 Receptor 1, 180kDa (PLA2R1) (AA 870-1130) antibodyPLA2R1 适用: 人 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-phospholipase A2 Receptor 1, 180kDa (PLA2R1) (AA 395-530) antibodyPLA2R1 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-phospholipase A2 Receptor 1, 180kDa (PLA2R1) (C-Term) antibodyPLA2R1 适用: 人 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
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应用备注
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Western blot, 0.25-0.5 μg/mL, Human
ELISA, 0.1-0.5 μg/mL, -
1. Ancian, P., Lambeau, G., Mattei, M.-G., Lazdunski, M. The human 180- kDa receptor for secretory phospholipases A2: molecular cloning, identification of a secreted soluble form, expression, and chromosomal localization. J. Biol. Chem. 270: 8963-8970, 1995. 2. Beck, L. H., Jr., Bonegio, R. G. B., Lambeau, G., Beck, D. M., Powell, D. W., Cummins, T. D., Klein, J. B., Salant, D. J. M-type phospholipase A2 receptor as target antigen in idiopathic membranous nephropathy. New Eng. J. Med. 361: 11-21, 2009. 3. Debiec, H., Ronco, P. PLA2R autoantibodies and PLA2R glomerular deposits in membranous nephropathy. (Letter) New Eng. J. Med. 364: 689-690, 2011. -
限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.
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储存条件
- 4 °C,-20 °C
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储存方法
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At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.
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- PLA2R1 (phospholipase A2 Receptor 1, 180kDa (PLA2R1))
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别名
- PLA2R1
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背景
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Synonyms: Interleukin-25, IL-25, Interleukin-17E, IL-17E, IL25, IL17E, UNQ3120/PRO10272
Tissue Specificity: Expressed at low levels in several tissues, including brain, kidney, lung, prostate, testis, spinal cord, adrenal gland, and trachea.
Background: Secretory phospholipase A2 receptor is an enzyme that in humans is encoded by the PLA2R1 gene. This gene represents a phospholipase A2 receptor. The encoded protein likely exists as both a transmembrane form and a soluble form. The transmembrane receptor may play a role in clearance of phospholipase A2, thereby inhibiting its action. Polymorphisms at this locus have been associated with susceptibility to idiopathic membranous nephropathy. Alternatively spliced transcript variants encoding different isoforms have been identified.
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分子量
- 169 kDa
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基因ID
- 22925
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UniProt
- Q13018
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途径
- Positive Regulation of Response to DNA Damage Stimulus
抗原
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