PLA2R1 抗体 (AA 395-530) (HRP)
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- 抗原 See all PLA2R1 抗体
- PLA2R1 (phospholipase A2 Receptor 1, 180kDa (PLA2R1))
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抗原表位
- AA 395-530
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This PLA2R1 antibody is conjugated to HRP
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应用范围
- ELISA
- 交叉反应
- 人
- 纯化方法
- >95%, Protein G purified
- 免疫原
- Recombinant Human Secretory phospholipase A2 receptor protein (395-530AA)
- 亚型
- IgG
- Top Product
- Discover our top product PLA2R1 Primary Antibody
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anti-phospholipase A2 Receptor 1, 180kDa (PLA2R1) (AA 1418-1487) antibody
PLA2R1 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-phospholipase A2 Receptor 1, 180kDa (PLA2R1) antibodyPLA2R1 适用: 人 WB, IF, IHC (p) 宿主: 小鼠 Monoclonal CL0474 unconjugated
anti-phospholipase A2 Receptor 1, 180kDa (PLA2R1) (AA 385-643) antibodyPLA2R1 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-phospholipase A2 Receptor 1, 180kDa (PLA2R1) (Internal Region) antibodyVerified PLA2R1 适用: 人 ELISA, FACS 宿主: 山羊 Polyclonal unconjugated
anti-phospholipase A2 Receptor 1, 180kDa (PLA2R1) (AA 385-643) antibodyPLA2R1 适用: 人 WB, IHC, IP, ICC 宿主: 小鼠 Monoclonal C6 unconjugated
anti-phospholipase A2 Receptor 1, 180kDa (PLA2R1) (AA 395-530) antibodyPLA2R1 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-phospholipase A2 Receptor 1, 180kDa (PLA2R1) (AA 870-1130) antibodyPLA2R1 适用: 人 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-phospholipase A2 Receptor 1, 180kDa (PLA2R1) (C-Term) antibodyPLA2R1 适用: 人 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
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- 应用备注
- Optimal working dilution should be determined by the investigator.
- 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
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Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4 - 储存液
- ProClin
- 注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C,-80 °C
- 储存方法
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- 抗原
- PLA2R1 (phospholipase A2 Receptor 1, 180kDa (PLA2R1))
- 别名
- PLA2R1 (PLA2R1 产品)
- 别名
- Pla2-r antibody, Pla2g1br antibody, Pla2r antibody, CLEC13C antibody, PLA2-R antibody, PLA2G1R antibody, PLA2IR antibody, PLA2R antibody, phospholipase A2 receptor 1 antibody, PLA2R1 antibody, Pla2r1 antibody
- 背景
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Background: Receptor for secretory phospholipase A2 (sPLA2). Acts as a receptor for phosholipase sPLA2-IB/PLA2G1B but not sPLA2-IIA/PLA2G2A. Also able to bind to snake PA2-like toxins. Although its precise function remains unclear, binding of sPLA2 to its receptor participates in both positive and negative regulation of sPLA2 functions as well as clearance of sPLA2. Binding of sPLA2-IB/PLA2G1B induces various effects depending on the cell type, such as activation of the mitogen-activated protein kinase (MAPK) cascade to induce cell proliferation, the production of lipid mediators, selective release of arachidonic acid in bone marrow-derived mast cells. In neutrophils, binding of sPLA2-IB/PLA2G1B can activate p38 MAPK to stimulate elastase release and cell adhesion. May be involved in responses in proinflammatory cytokine productions during endotoxic shock. Also has endocytic properties and rapidly internalizes sPLA2 ligands, which is particularly important for the clearance of extracellular sPLA2s to protect their potent enzymatic activities. The soluble secretory phospholipase A2 receptor form is circulating and acts as a negative regulator of sPLA2 functions by blocking the biological functions of sPLA2-IB/PLA2G1B.
Aliases: 180 kDa secretory phospholipase A2 receptor antibody, C-type lectin domain family 13 member C antibody, CLEC13C antibody, M type receptor antibody, M-type receptor antibody, Phospholipase A2 receptor 1 antibody, PLA2 R antibody, PLA2-R antibody, PLA2G1R antibody, PLA2IR antibody, PLA2R antibody, PLA2R_HUMAN antibody, PLA2R1 antibody, Soluble PLA2-R antibody, Soluble PLA2R antibody, Soluble secretory phospholipase A2 receptor antibody
- UniProt
- Q13018
- 途径
- Positive Regulation of Response to DNA Damage Stimulus
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