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MUC2 抗体 (AA 21-255)

This anti-MUC2 antibody is a 兔 多克隆 antibody detecting MUC2 in IHC 和 ELISA. Suitable for 人, 小鼠 和 大鼠.
产品编号 ABIN7600606
发货至: 中国

Quick Overview for MUC2 抗体 (AA 21-255) (ABIN7600606)

抗原

See all MUC2 抗体
MUC2 (Mucin 2, Oligomeric Mucus/gel-Forming (MUC2))

适用

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  • 22
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人, 小鼠, 大鼠

宿主

  • 79
  • 35

克隆类型

  • 58
  • 56
多克隆

标记

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  • 2
This MUC2 antibody is un-conjugated

应用范围

  • 67
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  • 4
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Immunohistochemistry (IHC), ELISA
  • 抗原表位

    • 7
    • 5
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    • 2
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    • 1
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    AA 21-255

    原理

    Anti-MUC2 Antibody

    交叉反应 (详细)

    No cross-reactivity with other proteins.

    产品特性

    Anti-MUC2 Antibody Picoband® (ABIN7600606). Tested in ELISA, IHC applications. This antibody reacts with Human, Mouse, Rat.

    纯化方法

    Immunogen affinity purified.

    免疫原

    E.coli-derived human MUC2 recombinant protein (Position: S21-C255).

    亚型

    IgG
  • 应用备注

    Immunohistochemistry(Paraffin-embedded Section), 2-5 μg/mL, Human, Mouse, Rat
    ELISA, 0.1-0.5 μg/mL, -
    1. Allen, A., Hutton, D. A., Pearson, J. P. The MUC2 gene product: a human intestinal mucin. Int. J. Biochem. Cell Biol. 30: 797-801, 1998. 2. Rousseau K, Byrne C, Kim YS, Gum JR, Swallow DM, Toribara NW (May 2004). "The complete genomic organization of the human MUC6 and MUC2 mucin genes". Genomics 83 (5): 936-9.

    限制

    仅限研究用
  • 状态

    Lyophilized

    溶解方式

    Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

    浓度

    500 μg/mL

    缓冲液

    Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

    储存条件

    4 °C,-20 °C

    储存方法

    At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
    It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.
  • 抗原

    MUC2 (Mucin 2, Oligomeric Mucus/gel-Forming (MUC2))

    别名

    MUC2

    背景

    Synonyms: Mucin-2, MUC-2, Intestinal mucin-2, MUC2, SMUC

    Tissue Specificity: Colon, small intestine, colonic tumors, bronchus, cervix and gall bladder.

    Background: Mucin 2, also known as MUC2, is a protein that in humans is encoded by the MUC2 gene. This gene encodes a member of the mucin protein family. It is mapped to 11p15.5. Mucin 2 is particularly prominent in the gut where it is secreted from goblet cells in the epithelial lining into the lumen of the large intestine. There, mucin 2, along with small amounts of related-mucin proteins, polymerizes into a gel of which 80 % by weight is oligosaccharide side-chains that are added as post-translational modifications to the mucin proteins. This gel provides an insoluble mucous barrier that serves to protect the intestinal epithelium. The primary function of the MUC2 gene product is to provide a protective barrier between the epithelial surfaces and the gut lumen. There is decreased expression of MUC2 in colonic cancer and defective polymerization of secreted mucin in ulcerative colitis.

    分子量

    38 kDa

    基因ID

    4583

    UniProt

    Q02817
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