MBL2 抗体 (AA 21-248)
Quick Overview for MBL2 抗体 (AA 21-248) (ABIN7600604)
抗原
See all MBL2 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 21-248
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原理
- Anti-MBL2 Antibody Picoband®
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交叉反应 (详细)
- No cross-reactivity with other proteins.
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产品特性
- Anti-MBL2 Antibody Picoband® (ABIN7600604). Tested in ELISA, WB, Flow Cytometry applications. This antibody reacts with Human. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
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纯化方法
- Immunogen affinity purified.
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免疫原
- E.coli-derived human MBL2 recombinant protein (Position: E21-I248).
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亚型
- IgG
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应用备注
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Western blot, 0.1-0.25 μg/mL, Human
Flow Cytometry (Fixed), 1-3 μg/1x106 cells, Human
ELISA, 0.1-0.5 μg/mL, -
1. Bodamer, O. A., Mitterer, G., Maurer, W., Pollak, A., Mueller, M. W., Schmidt, W. M. Evidence for an association between mannose-binding lectin 2 (MBL2) gene polymorphisms and pre-term birth. Genet. Med. 8: 518-524, 2006. 2. Buranawuti, K., Boyle, M. P., Cheng, S., Steiner, L. L., McDougal, K., Fallin, M. D., Merlo, C., Zeitlin, P. L., Rosenstein, B. J., Mogayzel, P. J., Jr., Wang, X., Cutting, G. R. Variants in mannose-binding lectin and tumour necrosis factor alpha affect survival in cystic fibrosis. J. Med. Genet. 44: 209-214, 2007. 3. Davies, J., Neth, O., Alton, E., Klein, N., Turner, M. Differential binding of mannose-binding lectin to respiratory pathogens in cystic fibrosis. Lancet 355: 1885-1886, 2000. -
限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.
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储存条件
- 4 °C,-20 °C
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储存方法
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At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.
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- MBL2 (Mannose-Binding Lectin (Protein C) 2, Soluble (MBL2))
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别名
- MBL2
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背景
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Synonyms: Mannose-binding protein C, MBP-C, Mannan-binding protein, RA-reactive factor P28A subunit, RARF/P28A, Mbl2
Tissue Specificity: Found only in peripheral nervous system Schwann cells.
Background: This gene encodes the soluble mannose-binding lectin or mannose-binding protein found in serum. The protein encoded belongs to the collectin family and is an important element in the innate immune system. The protein recognizes and binds to mannose and N-acetylglucosamine on many microorganisms, including bacteria, yeast, and viruses including influenza virus, HIV and SARS-CoV. This binding activates the classical complement pathway. Deficiencies of this gene have been associated with susceptibility to autoimmune and infectious diseases.
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分子量
- 26 kDa
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基因ID
- 4153
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UniProt
- P11226
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途径
- Complement System, Positive Regulation of Immune Effector Process
抗原
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