Cytokeratin 18 抗体 (AA 204-430)
Quick Overview for Cytokeratin 18 抗体 (AA 204-430) (ABIN7600573)
抗原
See all Cytokeratin 18 (KRT18) 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 204-430
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原理
- Anti-Cytokeratin 18 KRT18 Antibody Picoband®(monoclonal, 7I6)
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交叉反应 （详细）
- No cross-reactivity with other proteins.
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产品特性
- Anti-Cytokeratin 18 KRT18 Antibody Picoband® (monoclonal, 7I6) (ABIN7600573). Tested in Flow Cytometry, IF, IHC, IHC-F, ICC, WB applications. This antibody reacts with Human. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
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纯化方法
- Immunogen affinity purified.
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免疫原
- E.coli-derived human Cytokeratin 18 recombinant protein (Position: E204-H430). Human Cytokeratin 18 shares 87.7% and 85.9% amino acid (aa) sequence identity with mouse and rat Cytokeratin 18, respectively.
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亚型
- IgG1
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anti-Keratin 18 (KRT18) (AA 53-150) antibody
KRT18 适用: 人, 小鼠, 大鼠, Pig WB, FACS, ELISA, IHC (p), IHC (fro), IF (cc), IF (p) 宿主: 兔 Polyclonal unconjugated
anti-Keratin 18 (KRT18) antibodyKRT18 适用: 人 WB, ELISA, IHC (p), IP, ICC, ICFC 宿主: 小鼠 Monoclonal DC-10 unconjugated
anti-Keratin 18 (KRT18) antibodyKRT18 适用: 哺乳动物 WB, ELISA, IHC (p), IP, ICC, ICFC 宿主: 小鼠 Monoclonal C-04 unconjugated
anti-Keratin 18 (KRT18) (AA 238-396) antibodyKRT18 适用: 人 WB, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Keratin 18 (KRT18) (AA 1-423) antibodyKRT18 适用: 小鼠 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Keratin 18 (KRT18) (AA 238-396) antibodyKRT18 适用: 人 WB, IHC, IP, ICC 宿主: 小鼠 Monoclonal E4 unconjugated
anti-Keratin 18 (KRT18) (AA 72-380) antibodyKRT18 适用: 大鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Keratin 18 (KRT18) (AA 102-396) antibodyKRT18 适用: 人 WB, IHC, IF, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Keratin 18 (KRT18) antibodyKRT18 适用: 人 WB, IHC, IF, FACS, StM, ISt 宿主: 兔 Monoclonal KRT18-2808R unconjugated Recombinant Antibody
anti-Keratin 18 (KRT18) antibodyKRT18 适用: 人, 犬, Cat WB, IHC, IF, FACS, StM 宿主: 小鼠 Monoclonal DE-K18 unconjugated
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应用备注
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Western blot, 0.1-0.5 μg/mL, Human
Immunohistochemistry (Paraffin-embedded Section), 0.5-1 μg/mL, Human
Immunohistochemistry (Frozen Section), 0.5-1 μg/mL, Human
Immunocytochemistry/Immunofluorescence, 2 μg/mL, Human
Immunofluorescence, 2 μg/mL, Human
Flow Cytometry (Fixed), 1-3 μg/1x106 cells, Human
1. "Entrez Gene: KRT18 keratin 18". 2. Ku, N.-O., Wright, T. L., Terrault, N. A., Gish, R., Omary, M. B. Mutation of human keratin 18 in association with cryptogenic cirrhosis. J. Clin. Invest. 99: 19-23, 1997. 3. Ku, N.-O., Darling, J. M., Krams, S. M., Esquivel, C. O., Keeffe, E. B., Sibley, R. K., Lee, Y. M., Wright, T. L., Omary, M. B. Keratin 8 and 18 mutations are risk factors for developing liver disease of multiple etiologies. Proc. Nat. Acad. Sci. 100: 6063-6068, 2003. -
限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
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Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
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- Cytokeratin 18 (KRT18) (Keratin 18 (KRT18))
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别名
- KRT18
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背景
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Synonyms: Keratin, type I cytoskeletal 18, Cell proliferation-inducing gene 46 protein, Cytokeratin-18, CK-18, Keratin-18, K18, KRT18, CYK18, PIG46
Tissue Specificity: Expressed in colon, placenta, liver and very weakly in exocervix. Increased expression observed in lymph nodes of breast carcinoma.
Background: Keratin 18, mapped to 12q13.13, is a type I cytokeratin. It is, together with its filament partner keratin 8, perhaps the most commonly found products of the intermediate filament gene family. They are expressed in single layer epithelial tissues of the body. Mutations in this gene have been linked to cryptogenic cirrhosis. Two transcript variants encoding the same protein have been found for this gene.
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分子量
- 48 kDa
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基因ID
- 3875
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UniProt
- P05783
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途径
- Apoptosis, Caspase Cascade in Apoptosis
抗原
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