METAP2 抗体 (AA 201-474)
Quick Overview for METAP2 抗体 (AA 201-474) (ABIN7600568)
抗原
See all METAP2 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 201-474
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原理
- Anti-METAP2 Antibody Picoband®
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交叉反应 （详细）
- No cross-reactivity with other proteins.
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产品特性
- Anti-METAP2 Antibody Picoband® (ABIN7600568). Tested in ELISA, IHC, WB, applications. This antibody reacts with Human, Monkey, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
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纯化方法
- Immunogen affinity purified.
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免疫原
- E.coli-derived human METAP2 recombinant protein (Position: E201-R474).
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亚型
- IgG
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anti-Methionyl Aminopeptidase 2 (METAP2) (AA 2-212) antibody
METAP2 适用: 人 WB, IHC, IF, IHC (p), FACS 宿主: 小鼠 Monoclonal 1F6 unconjugated
anti-Methionyl Aminopeptidase 2 (METAP2) (AA 313-449) antibodyMETAP2 适用: 人 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Methionyl Aminopeptidase 2 (METAP2) (AA 1-478) antibodyMETAP2 适用: 人 WB, IF 宿主: 小鼠 Polyclonal unconjugated
anti-Methionyl Aminopeptidase 2 (METAP2) (AA 95-144) antibodyMETAP2 适用: 人, 小鼠, 大鼠, Cow, 犬, 豚鼠, 马, 斑马鱼, 猴, Bat, Hamster, Pig WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Methionyl Aminopeptidase 2 (METAP2) (C-Term) antibodyMETAP2 适用: 人, 小鼠 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Methionyl Aminopeptidase 2 (METAP2) antibodyMETAP2 适用: 人 ELISA, IHC 宿主: 兔 Monoclonal 8F2 unconjugated Recombinant Antibody
anti-Methionyl Aminopeptidase 2 (METAP2) antibodyMETAP2 适用: 人, 小鼠 WB 宿主: 兔 Polyclonal unconjugated
anti-Methionyl Aminopeptidase 2 (METAP2) (AA 1-220) antibodyMETAP2 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Methionyl Aminopeptidase 2 (METAP2) (N-Term) antibodyMETAP2 适用: 人, 小鼠, 大鼠 WB 宿主: 兔 Polyclonal unconjugated
anti-Methionyl Aminopeptidase 2 (METAP2) (AA 437-467), (C-Term) antibodyMETAP2 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal RB4959-4960 unconjugated
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应用备注
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Western blot, 0.1-0.25 μg/mL, Human, Mouse, Rat, Monkey
Immunohistochemistry, 2-5 μg/mL, Human
ELISA, 0.1-0.5 μg/mL, -
1. Datta, B., Chakrabarti, D., Roy, A. L., Gupta, N. K. Roles of a 67- kDa polypeptide in reversal of protein synthesis inhibition in heme-deficient reticulocyte lysate. Proc. Nat. Acad. Sci. 85: 3324-3328, 1988. 2. Griffith, E. C., Su, Z., Niwayama, S., Ramsay, C. A., Chang, Y- H., Liu, J. O. Molecular recognition of angiogenesis inhibitors fumagillin and ovalicin by methionine aminopeptidase 2. Proc. Nat. Acad. Sci. 95: 15183-15188, 1998. 3. Gross, M. B. Personal Communication. Baltimore, Md. 5/21/2014. -
限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.
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储存条件
- 4 °C,-20 °C
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储存方法
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At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.
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- METAP2 (Methionyl Aminopeptidase 2 (METAP2))
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别名
- METAP2
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背景
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Synonyms: DNA replication licensing factor MCM5, CDC46 homolog, P1-CDC46, MCM5, CDC46
Tissue Specificity: Ubiquitous.
Background: Methionine aminopeptidase 2 is an enzyme that in humans is encoded by the METAP2 gene. The protein encoded by this gene is a member of the methionyl aminopeptidase family. The encoded protein functions both by protecting the alpha subunit of eukaryotic initiation factor 2 from inhibitory phosphorylation and by removing the amino-terminal methionine residue from nascent proteins. Increased expression of this gene is associated with various forms of cancer, and the anti-cancer drugs fumagillin and ovalicin inhibit the protein by irreversibly binding to its active site. Inhibitors of this gene have also been shown to be effective for the treatment of obesity. A pseudogene of this gene is located on chromosome 2. Several transcript variants encoding different isoforms have been found for this gene.
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分子量
- 67 kDa
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基因ID
- 10988
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UniProt
- P50579
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途径
- Regulation of G-Protein Coupled Receptor Protein Signaling
抗原
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