LRRC32 抗体 (AA 20-544)
Quick Overview for LRRC32 抗体 (AA 20-544) (ABIN7600555)
抗原
See all LRRC32 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 20-544
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原理
- Anti-LRRC32 Picoband® Antibody
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交叉反应 (详细)
- No cross-reactivity with other proteins.
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产品特性
- Anti-LRRC32 Picoband® Antibody (ABIN7600555). Tested in ELISA, WB applications. This antibody reacts with Human. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
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纯化方法
- Immunogen affinity purified.
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免疫原
- E.coli-derived human LRRC32 recombinant protein (Position: H20-R544).
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亚型
- IgG
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应用备注
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Western blot, 0.25-0.5 μg/mL, Human
ELISA, 0.1-0.5 μg/mL, -
1. Lienart, S., Merceron, R., Vanderaa, C., Lambert, F., Colau, D., Stockis, J., van der Woning, B., De Haard, H., Saunders, M., Coulie, P. G., Savvides, S. N., Lucas, S. Structural basis of latent TGF-beta-1 presentation and activation by GARP on human regulatory T cells. Science 362: 952-956, 2018. 2. Ollendorff, V., Noguchi, T., deLapeyriere, O., Birnbaum, D. The GARP gene encodes a new member of the family of leucine-rich repeat-containing proteins. Cell Growth Diff. 5: 213-219, 1994. 3. Ollendorff, V., Szepetowski, P., Mattei, M.-G., Gaudray, P., Birnbaum, D. New gene in the homologous human 11q13-q14 and mouse 7F chromosomal regions. Mammalian Genome 2: 195-200, 1992. -
限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg NaN3.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
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Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
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- LRRC32 (Leucine Rich Repeat Containing 32 (LRRC32))
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别名
- LRRC32
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背景
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Synonyms: Transforming growth factor beta activator LRRC32, Garpin, Glycoprotein A repetitions predominant, GARP, Leucine-rich repeat-containing protein 32, LRRC32, D11S833E
Tissue Specificity: Heart, placenta, skeletal muscle, kidney, lung and pancreas.
Background: Leucine-rich repeat protein 32 (LRRC32), also known as GARP (glycoprotein A repetitions predominant), is an 80 kDa type I transmembrane glycoprotein. It is mapped to 11q13.5. This gene encodes a type I membrane protein which contains 20 leucine-rich repeats. Alterations in the chromosomal region 11q13-11q14 are involved in several pathologies.
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分子量
- 72 kDa
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基因ID
- 2615
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UniProt
- Q14392
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途径
- Activated T Cell Proliferation
抗原
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