PDIA6 抗体 (AA 20-440)
Quick Overview for PDIA6 抗体 (AA 20-440) (ABIN7600554)
抗原
See all PDIA6 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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                                            抗原表位
- AA 20-440
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                                            原理
- Anti-PDIA6 Antibody Picoband® (monoclonal, 3H5E7)
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                                            交叉反应 (详细)
- No cross-reactivity with other proteins.
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                                            产品特性
- Anti-PDIA6 Antibody Picoband® (monoclonal, 3H5E7) (ABIN7600554). Tested in Flow Cytometry, IF, IHC, ICC, WB applications. This antibody reacts with Human, Monkey. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
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                                            纯化方法
- Immunogen affinity purified.
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                                            免疫原
- E.coli-derived human PDIA6 recombinant protein (Position: L20-L440).
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                                            亚型
- IgG2b
 
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                                            应用备注
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                        Western blot, 0.25-0.5 μg/mL, Human, Monkey
 Immunohistochemistry(Paraffin-embedded Section), 2-5 μg/mL, Human
 Immunocytochemistry/Immunofluorescence, 5 μg/mL, Human
 Flow Cytometry (Fixed), 1-3 μg/1x106 cells, Human
 1. Chaudhuri, M. M., Tonin, P. N., Lewis, W. H., Srinivasan, P. R. The gene for a novel protein, a member of the protein disulphide isomerase/Form I phosphoinositide-specific phospholipase C family, is amplified in hydroxyurea-resistant cells. Biochem. J. 281: 645-650, 1992. 2. Hayano, T., Kikuchi, M. Cloning and sequencing of the cDNA encoding human P5. Gene 164: 377-378, 1995. 3. Hoshijima, K., Metherall, J. E., Grunwald, D. J. A protein disulfide isomerase expressed in the embryonic midline is required for left/right asymmetries. Genes Dev. 16: 2518-2529, 2002.
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                                            限制
- 仅限研究用
 
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                                            状态
- Lyophilized
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                                            溶解方式
- Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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                                            浓度
- 500 μg/mL
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                                            缓冲液
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl and 0.2 mg Na2HPO4.
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                                            储存条件
- 4 °C,-20 °C
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                                            储存方法
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                        At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. 
 It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.
 
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    - PDIA6 (Protein Disulfide Isomerase Family A, Member 6 (PDIA6))
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                                            别名
- PDIA6
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                                            背景
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                        Synonyms: Eukaryotic translation initiation factor 6, eIF-6, B (2)GCN homolog, B4 integrin interactor, CAB, p27 (BBP), EIF6, EIF3A, ITGB4BP, OK/SW-cl.27 Tissue Specificity: Expressed at very high levels in colon carcinoma with lower levels in normal colon and ileum and lowest levels in kidney and muscle. Background: This gene encodes a member of the disulfide isomerase (PDI) family of endoplasmic reticulum (ER) proteins that catalyze protein folding and thiol-disulfide interchange reactions. The encoded protein has an N-terminal ER-signal sequence, two catalytically active thioredoxin (TRX) domains, a TRX-like domain, and a C-terminal ER-retention sequence. This protein inhibits the aggregation of misfolded proteins and exhibits both isomerase and chaperone activity. Alternative splicing results in multiple transcript variants encoding different isoforms. 
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                                            分子量
- 48 kDa
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                                            基因ID
- 10130
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                                            UniProt
- Q15084
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                                            途径
- ER-Nucleus Signaling, Cell RedoxHomeostasis
 抗原
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