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PDIA6 抗体 (AA 20-440)

This anti-PDIA6 antibody is a 小鼠 单克隆 antibody detecting PDIA6 in WB, IHC, IF, FACS 和 ICC. Suitable for 人 和 猴.
产品编号 ABIN7600554
发货至: 中国

Quick Overview for PDIA6 抗体 (AA 20-440) (ABIN7600554)

抗原

See all PDIA6 抗体
PDIA6 (Protein Disulfide Isomerase Family A, Member 6 (PDIA6))

适用

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人, 猴

宿主

  • 33
  • 6
  • 1
小鼠

克隆类型

  • 27
  • 13
单克隆

标记

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This PDIA6 antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), Flow Cytometry (FACS), Immunocytochemistry (ICC)

克隆位点

3H5E7
  • 抗原表位

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    AA 20-440

    原理

    Anti-PDIA6 Antibody Picoband® (monoclonal, 3H5E7)

    交叉反应 (详细)

    No cross-reactivity with other proteins.

    产品特性

    Anti-PDIA6 Antibody Picoband® (monoclonal, 3H5E7) (ABIN7600554). Tested in Flow Cytometry, IF, IHC, ICC, WB applications. This antibody reacts with Human, Monkey. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

    纯化方法

    Immunogen affinity purified.

    免疫原

    E.coli-derived human PDIA6 recombinant protein (Position: L20-L440).

    亚型

    IgG2b
  • 应用备注

    Western blot, 0.25-0.5 μg/mL, Human, Monkey
    Immunohistochemistry(Paraffin-embedded Section), 2-5 μg/mL, Human
    Immunocytochemistry/Immunofluorescence, 5 μg/mL, Human
    Flow Cytometry (Fixed), 1-3 μg/1x106 cells, Human
    1. Chaudhuri, M. M., Tonin, P. N., Lewis, W. H., Srinivasan, P. R. The gene for a novel protein, a member of the protein disulphide isomerase/Form I phosphoinositide-specific phospholipase C family, is amplified in hydroxyurea-resistant cells. Biochem. J. 281: 645-650, 1992. 2. Hayano, T., Kikuchi, M. Cloning and sequencing of the cDNA encoding human P5. Gene 164: 377-378, 1995. 3. Hoshijima, K., Metherall, J. E., Grunwald, D. J. A protein disulfide isomerase expressed in the embryonic midline is required for left/right asymmetries. Genes Dev. 16: 2518-2529, 2002.

    限制

    仅限研究用
  • 状态

    Lyophilized

    溶解方式

    Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

    浓度

    500 μg/mL

    缓冲液

    Each vial contains 4 mg Trehalose, 0.9 mg NaCl and 0.2 mg Na2HPO4.

    储存条件

    4 °C,-20 °C

    储存方法

    At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
    It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.
  • 抗原

    PDIA6 (Protein Disulfide Isomerase Family A, Member 6 (PDIA6))

    别名

    PDIA6

    背景

    Synonyms: Eukaryotic translation initiation factor 6, eIF-6, B (2)GCN homolog, B4 integrin interactor, CAB, p27 (BBP), EIF6, EIF3A, ITGB4BP, OK/SW-cl.27

    Tissue Specificity: Expressed at very high levels in colon carcinoma with lower levels in normal colon and ileum and lowest levels in kidney and muscle.

    Background: This gene encodes a member of the disulfide isomerase (PDI) family of endoplasmic reticulum (ER) proteins that catalyze protein folding and thiol-disulfide interchange reactions. The encoded protein has an N-terminal ER-signal sequence, two catalytically active thioredoxin (TRX) domains, a TRX-like domain, and a C-terminal ER-retention sequence. This protein inhibits the aggregation of misfolded proteins and exhibits both isomerase and chaperone activity. Alternative splicing results in multiple transcript variants encoding different isoforms.

    分子量

    48 kDa

    基因ID

    10130

    UniProt

    Q15084

    途径

    ER-Nucleus Signaling, Cell RedoxHomeostasis
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