MPG 抗体 (AA 20-298)
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北京 101111
Quick Overview for MPG 抗体 (AA 20-298) (ABIN7600539)
抗原
See all MPG 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 20-298
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原理
- Anti-AAG/MPG Antibody
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交叉反应 （详细）
- No cross-reactivity with other proteins.
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产品特性
- Anti-AAG/MPG Antibody (ABIN7600539). Tested in ELISA, WB applications. This antibody reacts with Human. This is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications.
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纯化方法
- Immunogen affinity purified.
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免疫原
- E.coli-derived human AAG/MPG recombinant protein (Position: Q20-A298).
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亚型
- IgG
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anti-N-Methylpurine-DNA Glycosylase (MPG) (AA 1-90) antibody
MPG 适用: 人 WB, ELISA, IF, IHC (p) 宿主: 小鼠 Monoclonal 1E10 unconjugated
anti-N-Methylpurine-DNA Glycosylase (MPG) (AA 221-296) antibodyMPG 适用: 人 WB, ELISA, ICC, IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-N-Methylpurine-DNA Glycosylase (MPG) (AA 1-90) antibodyMPG 适用: 人 WB, ELISA, IF, IHC (p) 宿主: 小鼠 Monoclonal 1G6 unconjugated
anti-N-Methylpurine-DNA Glycosylase (MPG) (C-Term) antibodyVerified MPG 适用: 人 WB, ELISA, IHC 宿主: 山羊 Polyclonal unconjugated
anti-N-Methylpurine-DNA Glycosylase (MPG) (C-Term) antibodyMPG 适用: 人, Cow WB 宿主: 兔 Polyclonal unconjugated
anti-N-Methylpurine-DNA Glycosylase (MPG) (C-Term) antibodyMPG 适用: 人, 大鼠, 小鼠, Cow, 豚鼠, 兔, Hamster, Pig WB 宿主: 兔 Polyclonal unconjugated
anti-N-Methylpurine-DNA Glycosylase (MPG) antibodyMPG 适用: 人 WB, ICC, IF 宿主: 兔 Polyclonal unconjugated
anti-N-Methylpurine-DNA Glycosylase (MPG) (C-Term) antibodyMPG 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-N-Methylpurine-DNA Glycosylase (MPG) (AA 46-315) antibodyMPG 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-N-Methylpurine-DNA Glycosylase (MPG) (AA 32-300) antibodyMPG 适用: 大鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
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应用备注
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Western blot, 0.25-0.5 μg/mL/mL, Human
ELISA, 0.1-0.5 μg/mL/mL, Human
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.
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储存条件
- 4 °C,-20 °C
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储存方法
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At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.
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- MPG (N-Methylpurine-DNA Glycosylase (MPG))
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别名
- MPG
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背景
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Synonyms: Signal transducer and activator of transcription 1-alpha/beta,Transcription factor ISGF-3 components p91/p84,STAT1,
Tissue Specificity: In fetal tissues most abundant in spleen, brain stem and lung. Also present in most adult tissues where it is found mainly in lymphoid tissues.
Background: MPG(N-methylpurine-DNA glycosylase) also known as MDG, 3-METHYLADENINE DNA GLYCOSYLASE, 3MeAde DNA GLYCOSYLASE, AAG or APNG. The MPG gene is mapped to human chromosome 16 by analysis of a panel of DNAs from mouse/human and hamster/human hybrid cell lines.TheMPGgene was expressed in all cell lines and tissues examined, but was found at particularly high levels in a colon adenocarcinoma cell line(HT29). The completely characterized humanMPGgene was found to span 7 to 8 kb of genomic DNA and to be localized 75 kb upstream of the embryonic zeta-globin gene. To assess the contribution of Apng to the repair of several mutagenic lesions in vivo,Hang et al.(1997)biochemically analyzed cell-free extracts of tissues from mice with a targeted deletion of the Apng gene. Following treatment with DNA-methylating agents, increased persistence of 7-methylguanine(meG) was found in liver sections of APNG knockout mice in comparison with wildtype mice, demonstrating an in vivo phenotype for the APNG-null animals.
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分子量
- 37 kDa
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基因ID
- 4350
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UniProt
- P29372
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途径
- DNA Damage Repair
抗原
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