MPG 抗体 (AA 20-298)
Quick Overview for MPG 抗体 (AA 20-298) (ABIN7600539)
抗原
See all MPG 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 20-298
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原理
- Anti-AAG/MPG Antibody Picoband®
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交叉反应 （详细）
- No cross-reactivity with other proteins.
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产品特性
- Anti-AAG/MPG Antibody Picoband® (ABIN7600539). Tested in ELISA, WB applications. This antibody reacts with Human. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
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纯化方法
- Immunogen affinity purified.
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免疫原
- E.coli-derived human AAG/MPG recombinant protein (Position: Q20-A298).
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亚型
- IgG
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anti-N-Methylpurine-DNA Glycosylase (MPG) (AA 1-90) antibody
MPG 适用: 人 WB, ELISA, IF, IHC (p) 宿主: 小鼠 Monoclonal 1E10 unconjugated
anti-N-Methylpurine-DNA Glycosylase (MPG) (AA 221-296) antibodyMPG 适用: 人 WB, ELISA, IHC (p), ICC, IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-N-Methylpurine-DNA Glycosylase (MPG) (AA 1-90) antibodyMPG 适用: 人 WB, ELISA, IF, IHC (p) 宿主: 小鼠 Monoclonal 1G6 unconjugated
anti-N-Methylpurine-DNA Glycosylase (MPG) (C-Term) antibodyVerified MPG 适用: 人 WB, ELISA, IHC 宿主: 山羊 Polyclonal unconjugated
anti-N-Methylpurine-DNA Glycosylase (MPG) (C-Term) antibodyMPG 适用: 人, Cow WB 宿主: 兔 Polyclonal unconjugated
anti-N-Methylpurine-DNA Glycosylase (MPG) (C-Term) antibodyMPG 适用: 人, 大鼠, 小鼠, Cow, 豚鼠, 兔, Hamster, Pig WB 宿主: 兔 Polyclonal unconjugated
anti-N-Methylpurine-DNA Glycosylase (MPG) antibodyMPG 适用: 人 WB, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-N-Methylpurine-DNA Glycosylase (MPG) (C-Term) antibodyMPG 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-N-Methylpurine-DNA Glycosylase (MPG) (AA 46-315) antibodyMPG 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-N-Methylpurine-DNA Glycosylase (MPG) (AA 32-300) antibodyMPG 适用: 大鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
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应用备注
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Western blot, 0.25-0.5 μg/mL/mL, Human
ELISA, 0.1-0.5 μg/mL/mL, Human
1. Boosalis, M., Derfler, B., Call, K., Samson, L. Cloning of a human 3-methyladenine DNA glycosylase cDNA whose gene maps to human chromosome 16. (Abstract) Am. J. Hum. Genet. 49 (suppl.): 399 only, 1991. 2. Engelward, B. P., Weeda, G., Wyatt, M. D., Broekhof, J. L. M., de Wit, J., Donker, I., Allan, J. M., Gold, B., Hoeijmakers, J. H. J., Samson, L. D.Base excision repair deficient mice lacking the Aag alkyladenine DNA glycosylase. Proc. Nat. Acad. Sci. 94: 13087-13092, 1997. 3. Kielman, M. F., Smits, R., Bernini, L. F. Localization and characterization of the mouse alpha-globin locus control region. Genomics 21: 431-433, 1994. -
限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.
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储存条件
- 4 °C,-20 °C
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储存方法
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At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.
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- MPG (N-Methylpurine-DNA Glycosylase (MPG))
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别名
- MPG
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背景
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Synonyms: Signal transducer and activator of transcription 1-alpha/beta,Transcription factor ISGF-3 components p91/p84,STAT1,
Tissue Specificity: In fetal tissues most abundant in spleen, brain stem and lung. Also present in most adult tissues where it is found mainly in lymphoid tissues.
Background: MPG(N-methylpurine-DNA glycosylase) also known as MDG, 3-METHYLADENINE DNA GLYCOSYLASE, 3MeAde DNA GLYCOSYLASE, AAG or APNG. The MPG gene is mapped to human chromosome 16 by analysis of a panel of DNAs from mouse/human and hamster/human hybrid cell lines.TheMPGgene was expressed in all cell lines and tissues examined, but was found at particularly high levels in a colon adenocarcinoma cell line(HT29). The completely characterized humanMPGgene was found to span 7 to 8 kb of genomic DNA and to be localized 75 kb upstream of the embryonic zeta-globin gene. To assess the contribution of Apng to the repair of several mutagenic lesions in vivo,Hang et al.(1997)biochemically analyzed cell-free extracts of tissues from mice with a targeted deletion of the Apng gene. Following treatment with DNA-methylating agents, increased persistence of 7-methylguanine(meG) was found in liver sections of APNG knockout mice in comparison with wildtype mice, demonstrating an in vivo phenotype for the APNG-null animals.
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分子量
- 37 kDa
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基因ID
- 4350
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UniProt
- P29372
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途径
- DNA Damage Repair
抗原
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