IQGAP1 抗体 (AA 2-578)
Quick Overview for IQGAP1 抗体 (AA 2-578) (ABIN7600509)
抗原
See all IQGAP1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 2-578
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原理
- Anti-IQGAP1 Antibody Picoband®
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交叉反应 （详细）
- No cross-reactivity with other proteins.
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产品特性
- Anti-IQGAP1 Antibody Picoband® (ABIN7600509). Tested in ELISA, Flow Cytometry, IF, IHC, ICC, WB applications. This antibody reacts with Human. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
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纯化方法
- Immunogen affinity purified.
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免疫原
- E.coli-derived human IQGAP1 recombinant protein (Position: S2-H578).
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亚型
- IgG
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anti-IQ Motif Containing GTPase Activating Protein 1 (IQGAP1) (AA 611-710) antibody
IQGAP1 适用: 人 WB, ELISA, IF, IHC (p) 宿主: 小鼠 Monoclonal 2C5 unconjugated
anti-IQ Motif Containing GTPase Activating Protein 1 (IQGAP1) (AA 500-750) antibodyIQGAP1 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-IQ Motif Containing GTPase Activating Protein 1 (IQGAP1) (AA 1451-1550) antibodyIQGAP1 适用: 人, 大鼠, 兔 WB, ELISA, IF (p), IF (cc), IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-IQ Motif Containing GTPase Activating Protein 1 (IQGAP1) antibodyIQGAP1 适用: 人, 小鼠, 大鼠 IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-IQ Motif Containing GTPase Activating Protein 1 (IQGAP1) (N-Term) antibodyIQGAP1 适用: 人, 小鼠, 大鼠 WB, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-IQ Motif Containing GTPase Activating Protein 1 (IQGAP1) (N-Term) antibodyIQGAP1 适用: 人 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-IQ Motif Containing GTPase Activating Protein 1 (IQGAP1) antibodyIQGAP1 适用: 人, 小鼠 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-IQ Motif Containing GTPase Activating Protein 1 (IQGAP1) (N-Term) antibodyIQGAP1 适用: 人, 小鼠 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-IQ Motif Containing GTPase Activating Protein 1 (IQGAP1) (AA 793-808), (Intracellular) antibodyIQGAP1 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-IQ Motif Containing GTPase Activating Protein 1 (IQGAP1) (Internal Region) antibodyVerified IQGAP1 适用: 人 WB, ELISA 宿主: 山羊 Polyclonal unconjugated
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应用备注
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Western blot, 0.25-0.5 μg/mL, Human
Immunohistochemistry (Paraffin-embedded Section), 2-5 μg/mL, Human
Immunocytochemistry/Immunofluorescence, 5 μg/mL, Human
Flow Cytometry (Fixed), 1-3 μg/1x106 cells, Human
ELISA, 0.1-0.5 μg/mL, -
1. Briggs, M. W., Li, Z., Sacks, D. B. IQGAP1-mediated stimulation of transcriptional co-activation by beta-catenin is modulated by calmodulin. J. Biol. Chem. 277: 7453-7465, 2002. 2. Fukata, M., Watanabe, T., Noritake, J., Nakagawa, M., Yamaga, M., Kuroda, S., Matsuura, Y., Iwamatsu, A., Perez, F., Kaibuchi, K. Rac1 and Cdc42 capture microtubules through IQGAP1 and CLIP-170. Cell 109: 873-885, 2002. 3. Hart, M. J., Callow, M. G., Souza, B., Polakis, P. IQGAP1, a calmodulin-binding protein with a rasGAP-related domain, is a potential effector for cdc42Hs. EMBO J. 15: 2997-3005, 1996. -
限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl and 0.2 mg Na2HPO4.
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储存条件
- 4 °C,-20 °C
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储存方法
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Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
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- IQGAP1 (IQ Motif Containing GTPase Activating Protein 1 (IQGAP1))
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别名
- IQGAP1
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背景
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Synonyms: Ras GTPase-activating-like protein IQGAP1, p195, IQGAP1, KIAA0051
Tissue Specificity: Expressed in the placenta, lung, and kidney. A lower level expression is seen in the heart, liver, skeletal muscle and pancreas.
Background: Ras GTPase-activating-like protein IQGAP1 (IQGAP1) also known as p195 is a ubiquitously expressed protein that in humans is encoded by the IQGAP1 gene. It is mapped to 15q26.1. This gene encodes a member of the IQGAP family. The protein contains four IQ domains, one calponin homology domain, one Ras-GAP domain and one WW domain. It interacts with components of the cytoskeleton, with cell adhesion molecules, and with several signaling molecules to regulate cell morphology and motility. Expression of the protein is upregulated by gene amplification in two gastric cancer cell lines.
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分子量
- 195 kDa
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基因ID
- 8826
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UniProt
- P46940
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途径
- Signaling Events mediated by VEGFR1 and VEGFR2
抗原
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