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IQGAP1 抗体 (N-Term)

IQGAP1 适用: 人, 小鼠, 大鼠 WB, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN6256871
发货至: 中国
  • 抗原 See all IQGAP1 抗体
    IQGAP1 (IQ Motif Containing GTPase Activating Protein 1 (IQGAP1))
    抗原表位
    • 15
    • 8
    • 8
    • 5
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    N-Term
    适用
    • 64
    • 25
    • 20
    • 15
    • 1
    • 1
    人, 小鼠, 大鼠
    宿主
    • 58
    • 6
    • 1
    克隆类型
    • 49
    • 16
    多克隆
    标记
    • 27
    • 5
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    This IQGAP1 antibody is un-conjugated
    应用范围
    • 49
    • 24
    • 15
    • 14
    • 9
    • 7
    • 7
    • 6
    • 3
    • 2
    • 2
    • 1
    • 1
    Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunocytochemistry (ICC)
    特异性
    IQGAP1 Antibody detects endogenous levels of total IQGAP1.
    预测反应
    Pig,Bovine,Sheep,Rabbit,Dog
    纯化方法
    The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
    免疫原
    A synthesized peptide derived from human IQGAP1, corresponding to a region within N-terminal amino acids.
    亚型
    IgG
    Top Product
    Discover our top product IQGAP1 Primary Antibody
  • 应用备注
    WB 1:500-1:1000, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 mg/mL
    缓冲液
    Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    Store at -20 °C. Stable for 12 months from date of receipt.
    有效期
    12 months
  • 抗原
    IQGAP1 (IQ Motif Containing GTPase Activating Protein 1 (IQGAP1))
    别名
    IQGAP1 (IQGAP1 产品)
    别名
    HUMORFA01 antibody, SAR1 antibody, p195 antibody, AA682088 antibody, D7Ertd237e antibody, D7Ertd257e antibody, mKIAA0051 antibody, IQ motif containing GTPase activating protein 1 antibody, IQGAP1 antibody, Iqgap1 antibody
    背景

    Description: Plays a crucial role in regulating the dynamics and assembly of the actin cytoskeleton. Binds to activated CDC42 but does not stimulate its GTPase activity. It associates with calmodulin. Could serve as an assembly scaffold for the organization of a multimolecular complex that would interface incoming signals to the reorganization of the actin cytoskeleton at the plasma membrane. May promote neurite outgrowth (PubMed:15695813). May play a possible role in cell cycle regulation by contributing to cell cycle progression after DNA replication arrest (PubMed:20883816).

    Gene: IQGAP1

    分子量
    190 kDa
    基因ID
    8826
    UniProt
    P46940
    途径
    Signaling Events mediated by VEGFR1 and VEGFR2
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