WHSC1 抗体 (AA 2-478)
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- 抗原 See all WHSC1 抗体
- WHSC1 (Wolf-Hirschhorn Syndrome Candidate 1 (WHSC1))
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抗原表位
- AA 2-478
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适用
- 人, 猴
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This WHSC1 antibody is un-conjugated
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应用范围
- Western Blotting (WB), ELISA
- 原理
- Anti-WHSC1/NSD2 Antibody Picoband®
- 交叉反应 (详细)
- No cross-reactivity with other proteins.
- 产品特性
- Anti-WHSC1/NSD2 Antibody Picoband® (ABIN7600503). Tested in ELISA, WB applications. This antibody reacts with Human, Monkey. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
- 纯化方法
- Immunogen affinity purified.
- 免疫原
- E.coli-derived human WHSC1/NSD2 recombinant protein (Position: E2-A478).
- 亚型
- IgG
- Top Product
- Discover our top product WHSC1 Primary Antibody
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- 应用备注
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Western blot, 0.25-0.5 μg/mL, Human, Monkey
ELISA, 0.1-0.5 μg/mL, -
1. Baxendale, S., MacDonald, M. E., Mott, R., Francis, F., Lin, C., Kirby, S. F., James, M., Zehetner, G., Hummerich, H., Valdes, J., Collins, F. S., Deaven, L. J., Gusella, J. F., Lehrach, H., Bates, G. P. A cosmid contig and high resolution restriction map of the 2 megabase region containing the Huntington's disease gene. Nature Genet. 4: 181-186, 1993. 2. Chesi, M., Nardini, E., Brents, L. A., Schrock, E., Ried, T., Kuehl, W. M., Bergsagel, P. L. Frequent translocation t(4,14)(p16.3,q32.3) in multiple myeloma is associated with increased expression and activating mutations of fibroblast growth factor receptor 3. Nature Genet. 16: 260-264, 1997. 3. Jaffe, J. D., Wang, Y., Chan, H. M., Zhang, J., Huether, R., Kryukov, G. V., Bhang, H. C., Taylor, J. E., Hu, M., Englund, N. P., Yan, F., Wang, Z., and 20 others. Global chromatin profiling reveals NSD2 mutations in pediatric acute lymphoblastic leukemia. Nature Genet. 45: 1386-1391, 2013. - 限制
- 仅限研究用
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- 状态
- Lyophilized
- 溶解方式
- Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
- 浓度
- 500 μg/mL
- 缓冲液
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.
- 储存条件
- 4 °C,-20 °C
- 储存方法
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At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.
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- 抗原
- WHSC1 (Wolf-Hirschhorn Syndrome Candidate 1 (WHSC1))
- 别名
- NSD2 (WHSC1 产品)
- 背景
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Synonyms: Protein Bop, BH3-only protein, Retrotransposon Gag-like protein 10, RTL10, BOP, C22orf29
Tissue Specificity: Ubiquitously expressed.
Background: This gene encodes a protein that contains four domains present in other developmental proteins: a PWWP domain, an HMG box, a SET domain, and a PHD-type zinc finger. It is expressed ubiquitously in early development. Wolf-Hirschhorn syndrome (WHS) is a malformation syndrome associated with a hemizygous deletion of the distal short arm of chromosome 4. This gene maps to the 165 kb WHS critical region and has also been involved in the chromosomal translocation t(4,14)(p16.3,q32.3) in multiple myelomas. Alternative splicing of this gene results in multiple transcript variants encoding different isoforms. Some transcript variants are nonsense-mediated mRNA (NMD) decay candidates, hence not represented as reference sequences.
- 分子量
- 70 kDa, 160 kDa
- 基因ID
- 7468
- UniProt
- O96028
- 途径
- SARS-CoV-2 Protein Interactome
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