ALIX 抗体 (AA 2-330)
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北京 101111
Quick Overview for ALIX 抗体 (AA 2-330) (ABIN7600490)
抗原
See all ALIX (PDCD6IP) 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 2-330
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原理
- Anti-ALIX/PDCD6IP Antibody(monoclonal, 14D10)
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特异性
- No cross reactivity with other proteins.
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交叉反应 （详细）
- No cross-reactivity with other proteins.
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预测反应
- Human PDCD6IP shares?96.7%,95.2% amino?acid? (aa)?sequence?identity?with mouse?and rat PDCD6IP,respectively.
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产品特性
- Anti-ALIX/PDCD6IP Antibody.(monoclonal, 14D10)-1. Tested in Flow Cytometry, IF, IHC, ICC, WB applications. This antibody reacts with Human, Mouse, Rat.
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纯化方法
- Immunogen affinity purified.
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免疫原
- E.coli-derived human PDCD6IP recombinant protein (Position: A2-D330). Human PDCD6IP shares?96.7% and 95.2% amino?acid? (aa)?sequence?identity?with mouse?and rat PDCD6IP, respectively.
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亚型
- IgG2b
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anti-Programmed Cell Death 6 Interacting Protein (PDCD6IP) (AA 1-239) antibody
PDCD6IP 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Programmed Cell Death 6 Interacting Protein (PDCD6IP) (AA 1-868) antibodyPDCD6IP 适用: 人 WB, IF 宿主: 小鼠 Polyclonal unconjugated
anti-Programmed Cell Death 6 Interacting Protein (PDCD6IP) (AA 1-180) antibodyPDCD6IP 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-Programmed Cell Death 6 Interacting Protein (PDCD6IP) (AA 1-868) antibodyPDCD6IP 适用: 人 WB, IP 宿主: 兔 Polyclonal unconjugated
anti-Programmed Cell Death 6 Interacting Protein (PDCD6IP) (AA 174-383) antibodyPDCD6IP 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Programmed Cell Death 6 Interacting Protein (PDCD6IP) (AA 1-110) antibodyPDCD6IP 适用: 人 WB, ELISA, IF 宿主: 小鼠 Monoclonal 3C4 unconjugated
anti-Programmed Cell Death 6 Interacting Protein (PDCD6IP) antibodyKD Validated PDCD6IP 适用: 人 WB, FACS 宿主: 兔 Monoclonal 25GB3000 unconjugated Recombinant Antibody
anti-Programmed Cell Death 6 Interacting Protein (PDCD6IP) (AA 601-700) antibodyPDCD6IP 适用: 人, 小鼠, 大鼠 WB, ELISA, IF (cc), IF (p), IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Programmed Cell Death 6 Interacting Protein (PDCD6IP) (AA 1-868) antibodyPDCD6IP 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-Programmed Cell Death 6 Interacting Protein (PDCD6IP) antibodyPDCD6IP 适用: 人, 小鼠, 大鼠, 非洲爪蟾 WB, ELISA, IF, IP, IHC (p) 宿主: 小鼠 Monoclonal 3A9 unconjugated
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应用备注
- Western blot, 0.1-0.5 μg/mL, Human, Mouse, Rat Immunohistochemistry (Paraffin-embedded Section), 0.5-1 μg/mL, Human, Mouse, Rat Immunocytochemistry/Immunofluorescence, 2 μg/mL, Human Flow Cytometry (Fixed), 1-3 μg/1x106, Human
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
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Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles. -
有效期
- 12 months
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- ALIX (PDCD6IP) (Programmed Cell Death 6 Interacting Protein (PDCD6IP))
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别名
- PDCD6IP
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背景
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Background: Programmed cell death 6-interacting protein is a protein that in humans is encoded by the PDCD6IP gene. This gene encodes a protein that functions within the ESCRT pathway in the abscission stage of cytokinesis, in intralumenal endosomal vesicle formation, and in enveloped virus budding. Studies using mouse cells have shown that overexpression of this protein can block apoptosis. In addition, the product of this gene binds to the product of the PDCD6 gene, a protein required for apoptosis, in a calcium-dependent manner. This gene product also binds to endophilins, proteins that regulate membrane shape during endocytosis. Overexpression of this gene product and endophilins results in cytoplasmic vacuolization, which may be partly responsible for the protection against cell death. Several alternatively spliced transcript variants encoding different isoforms have been found for this gene.
Gene Full Name: programmed cell death 6 interacting protein
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分子量
- 96-100 kDa
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基因ID
- 10015
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UniProt
- Q8WUM4
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途径
- p53 Pathway, EGFR Signaling Pathway, Sensory Perception of Sound, Cellular Response to Molecule of Bacterial Origin, Tube Formation
抗原
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