PNN 抗体 (AA 2-241)
Quick Overview for PNN 抗体 (AA 2-241) (ABIN7600477)
抗原
See all PNN 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 2-241
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原理
- Anti-PNN/DRSP Antibody Picoband®
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交叉反应 （详细）
- No cross-reactivity with other proteins.
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产品特性
- Anti-PNN/DRSP Antibody Picoband® (ABIN7600477). Tested in ELISA, Flow Cytometry, WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
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纯化方法
- Immunogen affinity purified.
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免疫原
- E.coli-derived human PNN/DRSP recombinant protein (Position: A2-L241).
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亚型
- IgG
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anti-Pinin, Desmosome Associated Protein (PNN) antibody
PNN 适用: 人, 小鼠, 大鼠 IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Pinin, Desmosome Associated Protein (PNN) (AA 201-300) antibodyPNN 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 2B4 unconjugated
anti-Pinin, Desmosome Associated Protein (PNN) (Internal Region) antibodyPNN 适用: 人, 小鼠 WB, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Pinin, Desmosome Associated Protein (PNN) (AA 209-239) antibodyPNN 适用: 人 WB, IF, IHC (p) 宿主: 兔 Polyclonal RB17516 unconjugated
anti-Pinin, Desmosome Associated Protein (PNN) (AA 216-248), (Middle Region) antibodyPNN 适用: 人 WB, IF, IHC (p), EIA 宿主: 兔 Polyclonal unconjugated
anti-Pinin, Desmosome Associated Protein (PNN) (Internal Region) antibodyPNN 适用: 人 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Pinin, Desmosome Associated Protein (PNN) antibodyPNN 适用: 人, 小鼠 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Pinin, Desmosome Associated Protein (PNN) (AA 201-300) antibodyPNN 适用: 人 WB, ELISA 宿主: 小鼠 Polyclonal unconjugated
anti-Pinin, Desmosome Associated Protein (PNN) (AA 80-129) antibodyPNN 适用: 人, 小鼠, 大鼠, Cow, 豚鼠, 兔, 马 WB 宿主: 兔 Polyclonal unconjugated
anti-Pinin, Desmosome Associated Protein (PNN) (Internal Region) antibodyPNN 适用: 人, 小鼠 WB, ELISA 宿主: 兔 Polyclonal unconjugated
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应用备注
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Western blot, 0.1-0.25 μg/mL, Human, Mouse, Rat
Flow Cytometry (Fixed), 1-3 μg/1x106 cells, Human
ELISA, 0.1-0.5 μg/mL, -
1. Brandner, J. M., Reidenbach, S., Franke, W. W. Evidence that 'pinin, reportedly a differentiation-specific desmosomal protein, is actually a widespread nuclear protein. Differentiation 62: 119-127, 1997. 2. Brandner, J. M., Reidenbach, S., Kuhn, C., Franke, W. W. Identification and characterization of a novel kind of nuclear protein occurring free in nucleoplasm and in ribonucleoprotein structures of the 'speckle' type. Europ. J. Cell Biol. 75: 295-308, 1998. 3. Degen, W. G. J., Agterbos, M. A., Muyrers, J. P. P., Bloemers, H. P. J., Swart, G. W. M. memA/DRS, a putative mediator of multiprotein complexes, is overexpressed in the metastasizing human melanoma cell lines BLM and MV3. Biochim. Biophys. Acta 1444: 384-394, 1999. -
限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.01 mg Sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
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Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
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- PNN (Pinin, Desmosome Associated Protein (PNN))
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别名
- PNN
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背景
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Synonyms: Neutrophil cytosol factor 1, NCF-1, 47 kDa autosomal chronic granulomatous disease protein, 47 kDa neutrophil oxidase factor, NCF-47K, Neutrophil NADPH oxidase factor 1, Nox organizer 2, Nox-organizing protein 2, SH3 and PX domain-containing protein 1A, p47-phox, NCF1, NOXO2, SH3PXD1A
Tissue Specificity: Detected in peripheral blood monocytes and neutrophils (at protein level).
Background: Pinin is a protein that in humans is encoded by the PNN gene. By yeast 2-hybrid analysis of HeLa cells, followed by sequence analysis, it was found that epitope-tagged human PNN interacted with the serine/arginine (SR)-rich proteins SRP75 (SRSF4, 601940), SRM300 (SRRM2, 606032), and SRRP130 (PNISR, 616653). Truncation analysis revealed that the polyserine/RS domain of PNN and flanking sequences participated in binding to these SR proteins. The 4 proteins colocalized in the nucleus of HCE-T cells, and overexpression of any of these proteins affected the distribution of the others between nuclear speckles and nucleoplasm.
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分子量
- 82 kDa
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基因ID
- 5411
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UniProt
- Q9H307
抗原
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