SKP1 抗体 (AA 2-128)
Quick Overview for SKP1 抗体 (AA 2-128) (ABIN7600465)
抗原
See all SKP1 抗体适用
宿主
克隆类型
标记
应用范围
-
-
抗原表位
- AA 2-128
-
原理
- Anti-SKP1 Antibody Picoband®
-
交叉反应 （详细）
- No cross-reactivity with other proteins.
-
产品特性
- Anti-SKP1 Antibody Picoband® (ABIN7600465). Tested in ELISA, IHC, WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
-
纯化方法
- Immunogen affinity purified.
-
免疫原
- E.coli-derived human SKP1 recombinant protein (Position: P2-K128).
-
亚型
- IgG
-
-
anti-S-Phase Kinase-Associated Protein 1 (SKP1) antibody
SKP1 适用: 人 WB, ELISA, IHC, ICC, FACS 宿主: 小鼠 Monoclonal 4E11 unconjugated
anti-S-Phase Kinase-Associated Protein 1 (SKP1) (Internal Region) antibodySKP1 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-S-Phase Kinase-Associated Protein 1 (SKP1) (AA 53-160) antibodySKP1 适用: 人 WB, ELISA, IF 宿主: 小鼠 Monoclonal 1H8 unconjugated
anti-S-Phase Kinase-Associated Protein 1 (SKP1) (AA 1-163) antibodySKP1 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-S-Phase Kinase-Associated Protein 1 (SKP1) (AA 1-163) antibodySKP1 适用: 人, 大鼠, 猴, 小鸡, Cow, 非洲爪蟾 WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-S-Phase Kinase-Associated Protein 1 (SKP1) antibodySKP1 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-S-Phase Kinase-Associated Protein 1 (SKP1) (AA 1-160) antibodySKP1 适用: 人 WB, PLA 宿主: 兔 Polyclonal unconjugated
anti-S-Phase Kinase-Associated Protein 1 (SKP1) (AA 81-163) antibodySKP1 适用: 小鼠, 大鼠 WB, ELISA, IF (cc), IF (p), IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-S-Phase Kinase-Associated Protein 1 (SKP1) (AA 1-163) antibodySKP1 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-S-Phase Kinase-Associated Protein 1 (SKP1) (AA 2-163) antibodySKP1 适用: 人 WB, ELISA 宿主: 兔 Polyclonal unconjugated
-
-
应用备注
-
Western blot, 0.25-0.5 μg/mL, Human, Mouse, Rat
Immunohistochemistry (Paraffin-embedded Section), 0.5-1 μg/mL, Human, Mouse, Rat
ELISA, 0.1-0.5 μg/mL, -
1. Arai, T., Kasper, J. S., Skaar, J. R., Ali, S. H., Takahashi, C., DeCaprio, J. A. Targeted disruption of p185/Cul7 gene results in abnormal vascular morphogenesis. Proc. Nat. Acad. Sci. 100: 9855-9860, 2003. 2. Bai, C., Sen, P., Hofmann, K., Ma, L., Goebl, M., Harper, J. W., Elledge, S. J. SKP1 connects cell cycle regulators to the ubiquitin proteolysis machinery through a novel motif, the F-box. Cell 86: 263-274, 1996. 3. Chen, H., Thalmann, I., Adams, J. C., Avraham, K. B., Copeland, N. G., Jenkins, N. A., Beier, D. R., Corey, D. P., Thalmann, R., Duyk, G. M. cDNA cloning, tissue distribution and chromosomal localization of Ocp2, a gene encoding a putative transcription-associated factor predominantly expressed in the auditory organs. Genomics 27: 389-398, 1995. -
限制
- 仅限研究用
-
-
-
状态
- Lyophilized
-
溶解方式
- Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
-
浓度
- 500 μg/mL
-
缓冲液
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.
-
储存液
- Sodium azide
-
注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
储存条件
- 4 °C,-20 °C
-
储存方法
-
Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
-
-
- SKP1 (S-Phase Kinase-Associated Protein 1 (SKP1))
-
别名
- SKP1
-
背景
-
Synonyms: S-phase kinase-associated protein 1, Cyclin-A/CDK2-associated protein p19, P19a, Organ of Corti protein 2, OCP-2, Organ of Corti protein II, OCP-II, RNA polymerase II elongation factor-like protein, SIII, Transcription elongation factor B polypeptide 1-like, p19skp1, SKP1, EMC19, OCP2, SKP1A, TCEB1L
Tissue Specificity: Ubiquitously expressed.
Background: Skp1 (S-phase kinase-associated protein 1) is a small protein of approximately 160 amino acids. It is mapped to 5q31.1. This gene encodes a component of SCF complexes, which are composed of this protein, cullin 1, a ring-box protein, and one member of the F-box family of proteins. This protein binds ly to the F-box motif found in F-box proteins. SCF complexes are involved in the regulated ubiquitination of specific protein substrates, which targets them for degradation by the proteosome. Specific F-box proteins recognize different target protein (s), and many specific SCF substrates have been identified including regulators of cell cycle progression and development. Studies have also characterized the protein as an RNA polymerase II elongation factor. Alternative splicing of this gene results in two transcript variants. A related pseudogene has been identified on chromosome 7.
-
分子量
- 19 kDa
-
基因ID
- 6500
-
UniProt
- P63208
-
途径
- Cell Division Cycle, Hedgehog Signaling, Mitotic G1-G1/S Phases
抗原
-
