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RRP8 抗体 (AA 199-456)

This anti-RRP8 antibody is a 兔 多克隆 antibody detecting RRP8 in WB, ELISA, IF, ICC 和 FACS. Suitable for 人, 大鼠 和 小鼠.
产品编号 ABIN7600459
发货至: 中国

Quick Overview for RRP8 抗体 (AA 199-456) (ABIN7600459)

抗原

See all RRP8 抗体
RRP8 (Ribosomal RNA Processing 8 (RRP8))

适用

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人, 大鼠, 小鼠

宿主

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克隆类型

  • 23
多克隆

标记

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This RRP8 antibody is un-conjugated

应用范围

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Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunocytochemistry (ICC), Flow Cytometry (FACS)
  • 抗原表位

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    AA 199-456

    原理

    Anti-RRP8 Antibody Picoband®

    交叉反应 (详细)

    No cross-reactivity with other proteins.

    产品特性

    Anti-RRP8 Antibody Picoband® (ABIN7600459). Tested in ELISA, Flow Cytometry, IF, ICC, WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

    纯化方法

    Immunogen affinity purified.

    免疫原

    E.coli-derived human RRP8 recombinant protein (Position: K199-R456).

    亚型

    IgG
  • 应用备注

    Western blot, 0.25-0.5 μg/mL, Human, Mouse, Rat
    Immunocytochemistry/Immunofluorescence, 5 μg/mL, Human
    Flow Cytometry (Fixed), 1-3 μg/1x106 cells, Human
    ELISA, 0.1-0.5 μg/mL, -
    1. Hartz, P. A. Personal Communication. Baltimore, Md. 5/29/2014. 2. Ishikawa, K., Nagase, T., Nakajima, D., Seki, N., Ohira, M., Miyajima, N., Tanaka, A., Kotani, H., Nomura, N., Ohara, O. Prediction of the coding sequences of unidentified human genes. VIII. 78 new cDNA clones from brain which code for large proteins in vitro. DNA Res. 4: 307-313, 1997. 3. Murayama, A., Ohmori, K., Fujimura, A., Minami, H., Yasuzawa-Tanaka, K., Kuroda, T., Oie, S., Daitoku, H., Okuwaki, M., Nagata, K., Fukamizu, A., Kimura, K., Shimizu, T., Yanagisawa, J. Epigenetic control of rDNA loci in response to intracellular energy status. Cell 133: 627-639, 2008.

    限制

    仅限研究用
  • 状态

    Lyophilized

    溶解方式

    Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

    浓度

    500 μg/mL

    缓冲液

    Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

    储存条件

    4 °C,-20 °C

    储存方法

    At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
    It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.
  • 抗原

    RRP8 (Ribosomal RNA Processing 8 (RRP8))

    别名

    RRP8

    背景

    Synonyms: Interleukin-36 alpha, FIL1 epsilon, Interleukin-1 epsilon, IL-1 epsilon, Interleukin-1 family member 6, IL-1F6, IL36A, FIL1E, IL1E, IL1F6

    Tissue Specificity: Expressed in immune system and fetal brain, but not in other tissues tested or in multiple hematopoietic cell lines. Predominantly expressed in skin keratinocytes but not in fibroblasts, endothelial cells or melanocytes. Increased in lesional psoriasis skin.

    Background: Ribosomal RNA-processing protein 8 is a protein that in humans is encoded by the RRP8 gene. Enables methylated histone binding activity. Involved in several processes, including cellular response to glucose starvation, intrinsic apoptotic signaling pathway by p53 class mediator, and regulation of gene expression. Located in several cellular components, including cytosol, nuclear lumen, and rDNA heterochromatin. Part of chromatin silencing complex.

    分子量

    65 kDa

    基因ID

    23378

    UniProt

    O43159
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