RRP8 抗体 (N-Term)
Our Local Distributor
北京 101111
Quick Overview for RRP8 抗体 (N-Term) (ABIN2791071)
抗原
See all RRP8 抗体适用
宿主
克隆类型
标记
应用范围
-
-
抗原表位
- N-Term
-
原理
- RRP8 Antibody - N-terminal region
-
序列
- GKKGKKKCQK QGPPCSDSEE EVERKKKCHK QALVGSDSAE DEKRKRKCQK
-
预测反应
- Cow: 83%, Horse: 85%, Human: 100%, Rabbit: 85%, Rat: 93%
-
产品特性
- This is a rabbit polyclonal antibody against RRP8. It was validated on Western Blot.
-
纯化方法
- Affinity Purified
-
免疫原
- The immunogen is a synthetic peptide directed towards the N-terminal region of Human RRP8
-
-
anti-Ribosomal RNA Processing 8 (RRP8) antibody
RRP8 适用: 人, 大鼠, 小鼠 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Ribosomal RNA Processing 8 (RRP8) (AA 1-456) antibodyRRP8 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-Ribosomal RNA Processing 8 (RRP8) (AA 199-456) antibodyRRP8 适用: 人, 大鼠, 小鼠 WB, ELISA, IHC, FACS, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Ribosomal RNA Processing 8 (RRP8) (AA 271-320) antibodyRRP8 适用: 人 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Ribosomal RNA Processing 8 (RRP8) (AA 89-138) antibodyRRP8 适用: 人 WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Ribosomal RNA Processing 8 (RRP8) (AA 1-50) antibodyRRP8 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Ribosomal RNA Processing 8 (RRP8) (AA 100-149) antibodyRRP8 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
-
-
应用备注
- Optimal working dilution should be determined by the investigator.
-
说明
-
We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP68566-100UG
-
限制
- 仅限研究用
-
-
-
状态
- Liquid
-
浓度
- 0.5 mg/mL
-
缓冲液
- Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
-
储存液
- Sodium azide
-
注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
注意事项
- prevent freeze-thaw cycles
-
储存条件
- 4 °C,-20 °C
-
储存方法
- For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.
-
-
- RRP8 (Ribosomal RNA Processing 8 (RRP8))
-
别名
- RRP8
-
背景
-
Background Information: RRP8 is an essential component of the eNoSC (energy-dependent nucleolar silencing) complex, a complex that mediates silencing of rDNA in response to intracellular energy status and acts by recruiting histone-modifying enzymes. The eNoSC complex is able to sense the energy status of cell: upon glucose starvation, elevation of NAD+/NADP+ ratio activates SIRT1, leading to histone H3 deacetylation followed by dimethylation of H3 at 'Lys-9' (H3K9me2) by SUV39H1 and the formation of silent chromatin in the rDNA locus. In the complex, RRP8 binds to H3K9me2 and probably acts as a methyltransferase. Its substrates are however unknown.
Alternative Symbols: NML, KIAA0409
Protein Name: Ribosomal RNA-processing protein 8
-
分子量
- 50kDa
-
基因ID
- 23378
-
NCBI登录号
- NP_056139
-
UniProt
- O43159
抗原
-
