GDF15 抗体 (AA 189-302)
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北京 101111
Quick Overview for GDF15 抗体 (AA 189-302) (ABIN7600395)
抗原
See all GDF15 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 189-302
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原理
- Anti-Gdf15 Antibody
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产品特性
- Anti-Gdf15 Antibody (ABIN7600395). Tested in WB, Flow Cytometry, ELISA applications. This antibody reacts with Mouse, Rat. This is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications.
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纯化方法
- Immunogen affinity purified.
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免疫原
- E.coli-derived mouse Gdf15 recombinant protein (Position: S189-A302). Mouse Gdf15 shares 69.1% and 96.5% amino acid (aa) sequence identity with human and rat Gdf15, respectively.
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亚型
- IgG
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应用备注
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Western blot, 0.1-0.25 μg/mL, Mouse, Rat
ELISA, 0.1-0.5 μg/mL, -
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.
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储存条件
- 4 °C,-20 °C
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储存方法
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At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.
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- GDF15 (Growth Differentiation Factor 15 (GDF15))
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别名
- Gdf15
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背景
- Growth/differentiation factor 15 is a protein that in humans is encoded by the GDF15 gene. This gene encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate each subunit of the disulfide-linked homodimer. The protein is expressed in a broad range of cell types, acts as a pleiotropic cytokine and is involved in the stress response program of cells after cellular injury. Increased protein levels are associated with disease states such as tissue hypoxia, inflammation, acute injury and oxidative stress. Mice lacking a functional copy of this gene exhibit progressive loss of motor neurons, and more rapid blood clot formation.
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分子量
- 34 kDa
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基因ID
- 23886
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UniProt
- Q9Z0J7
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途径
- SARS-CoV-2 Protein Interactome
抗原
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