GLIS3 抗体 (AA 184-765)
Quick Overview for GLIS3 抗体 (AA 184-765) (ABIN7600381)
抗原
See all GLIS3 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 184-765
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原理
- Anti-GLIS3 Antibody Picoband®
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交叉反应 （详细）
- No cross-reactivity with other proteins.
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产品特性
- Anti-GLIS3 Antibody Picoband® (ABIN7600381). Tested in ELISA, WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
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纯化方法
- Immunogen affinity purified.
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免疫原
- E.coli-derived human GLIS3 recombinant protein (Position: A184-P765).
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亚型
- IgG
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anti-GLIS Family Zinc Finger 3 (GLIS3) (AA 101-200) antibody
GLIS3 适用: 人, 大鼠, 绵羊 WB, ELISA, FACS, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-GLIS Family Zinc Finger 3 (GLIS3) (AA 527-663) antibodyGLIS3 适用: 人 ELISA, IF, IHC 宿主: 兔 Polyclonal unconjugated
anti-GLIS Family Zinc Finger 3 (GLIS3) (Internal Region) antibodyGLIS3 适用: 人 WB, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-GLIS Family Zinc Finger 3 (GLIS3) (N-Term) antibodyGLIS3 适用: 人, 豚鼠, 马, 猴 WB 宿主: 兔 Polyclonal unconjugated
anti-GLIS Family Zinc Finger 3 (GLIS3) (C-Term) antibodyGLIS3 适用: 人, 犬, 兔, Cow WB 宿主: 兔 Polyclonal unconjugated
anti-GLIS Family Zinc Finger 3 (GLIS3) (AA 606-775) antibodyGLIS3 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-GLIS Family Zinc Finger 3 (GLIS3) (N-Term) antibodyGLIS3 适用: 人, 小鼠, 大鼠, 犬 WB 宿主: 兔 Polyclonal unconjugated
anti-GLIS Family Zinc Finger 3 (GLIS3) (C-Term) antibodyGLIS3 适用: 人, 小鼠, 大鼠 WB 宿主: 兔 Polyclonal unconjugated
anti-GLIS Family Zinc Finger 3 (GLIS3) (C-Term) antibodyGLIS3 适用: 人, 小鼠, 大鼠, 犬, 豚鼠, 马, 兔, Cow WB 宿主: 兔 Polyclonal unconjugated
anti-GLIS Family Zinc Finger 3 (GLIS3) (N-Term) antibodyGLIS3 适用: 人, 小鼠, 大鼠, 犬, 豚鼠, 马, 兔 WB, IHC 宿主: 兔 Polyclonal unconjugated
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应用备注
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Western blot, 0.25-0.5 μg/mL/mL, Human, Mouse, Rat
ELISA, 0.1-0.5 μg/mL/mL, Human
1. Beak, J. Y., Kang, H. S., Kim, Y.-S., Jetten, A. M. Functional analysis of the zinc finger and activation domains of Glis3 and mutant Glis3(NDH1). Nucleic Acids Res. 36: 1690-1702, 2008. 2. Dimitri, P., Habeb, A. M., Gurbuz, F., Millward, A., Wallis, S., Moussa, K., Akcay, T., Taha, D., Hogue, J., Slavotinek, A., Wales, J. K. H., Shetty, A., Hawkes, D., Hattersley, A. T., Ellard, S., De Franco, E. Expanding the clinical spectrum associated with GLIS3 mutations. J. Clin. Endocr. Metab. 100: E1362-E1369, 2015. Note: Electronic Article. Erratum: J. Clin. Endocr. Metab. 100: 4685 only, 2015. 3. Dimitri, P., Warner, J. T., Minton, J. A. L., Patch, A. M., Ellard, S., Hattersley, A. T., Barr, S., Hawkes, D., Wales, J. K., Gregory, J. W. Novel GLIS3 mutations demonstrate an extended multisystem phenotype. Europ. J. Endocr. 164: 437-443, 2011. -
限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.
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储存条件
- 4 °C,-20 °C
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储存方法
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At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.
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- GLIS3 (GLIS Family Zinc Finger 3 (GLIS3))
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别名
- GLIS3
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背景
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Synonyms: Tissue factor pathway inhibitor 2,TFPI-2,Placental protein 5,PP5,TFPI2,
Tissue Specificity: Umbilical vein endothelial cells, liver, placenta, heart, pancreas, and maternal serum at advanced pregnancy.
Background: Zinc finger protein GLI3 is a protein that in humans is encoded by the GLI3 gene. This gene is a member of the GLI-similar zinc finger protein family and encodes a nuclear protein with five C2H2-type zinc finger domains. This protein functions as both a repressor and activator of transcription and is specifically involved in the development of pancreatic beta cells, the thyroid, eye, liver and kidney. Mutations in this gene have been associated with neonatal diabetes and congenital hypothyroidism (NDH). Alternatively spliced variants that encode different protein isoforms have been described but the full-length nature of only two have been determined.
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分子量
- 84 kDa
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基因ID
- 169792
抗原
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