RRN3 抗体 (AA 184-651)
Quick Overview for RRN3 抗体 (AA 184-651) (ABIN7600380)
抗原
See all RRN3 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 184-651
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原理
- Anti-RRN3 Antibody Picoband®
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产品特性
- Anti-RRN3 Antibody Picoband® (ABIN7600380). Tested in WB, Flow Cytometry, ELISA applications. This antibody reacts with Human. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
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纯化方法
- Immunogen affinity purified.
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免疫原
- E.coli-derived human RRN3 recombinant protein (Position: D184-L651). Human RRN3 shares 87.4% amino acid (aa) sequence identity with mouse RRN3.
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anti-RRN3 RNA Polymerase I Transcription Factor (RRN3) (AA 525-631) antibody
RRN3 适用: 人 WB, ELISA 宿主: 小鼠 Polyclonal unconjugated
anti-RRN3 RNA Polymerase I Transcription Factor (RRN3) (AA 525-631) antibodyRRN3 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 3H5 unconjugated
anti-RRN3 RNA Polymerase I Transcription Factor (RRN3) (AA 1-106) antibodyRRN3 适用: 人 WB, IF 宿主: 小鼠 Polyclonal unconjugated
anti-RRN3 RNA Polymerase I Transcription Factor (RRN3) (AA 331-380) antibodyRRN3 适用: 人, 小鼠, 大鼠, 兔, 豚鼠, Cow, 马 WB 宿主: 兔 Polyclonal unconjugated
anti-RRN3 RNA Polymerase I Transcription Factor (RRN3) (C-Term) antibodyRRN3 适用: 人, 小鼠, 大鼠, 兔, 豚鼠, Cow, 犬, 马 WB 宿主: 兔 Polyclonal unconjugated
anti-RRN3 RNA Polymerase I Transcription Factor (RRN3) (Middle Region) antibodyRRN3 适用: 人, 小鼠, 大鼠, 兔, 豚鼠 WB 宿主: 兔 Polyclonal unconjugated
anti-RRN3 RNA Polymerase I Transcription Factor (RRN3) (C-Term) antibodyRRN3 适用: 人, 小鼠, 大鼠, 兔, 豚鼠, Cow, 犬, 马, Saccharomyces cerevisiae WB 宿主: 兔 Polyclonal unconjugated
anti-RRN3 RNA Polymerase I Transcription Factor (RRN3) (AA 602-651), (pSer649) antibodyRRN3 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
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应用备注
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Western blot, 0.25-0.5 μg/mL, Human
Flow Cytometry (Fixed), 1-3 μg/1x106 cells, Human
ELISA, 0.1-0.5 μg/mL, -
1. Mayer, C., Bierhoff, H., Grummt, I. The nucleolus as a stress sensor: JNK2 inactivates the transcription factor TIF-IA and down-regulates rRNA synthesis. Genes Dev. 19: 933-941, 2005. 2. Moorefield, B., Greene, E. A., Reeder, R. H. RNA polymerase I transcription factor Rrn3 is functionally conserved between yeast and human. Proc. Nat. Acad. Sci. 97: 4724-4729, 2000. 3. Yuan, X., Zhou, Y., Casanova, E., Chai, M., Kiss, E., Grone, H.-J., Schutz, G., Grummt, I. Genetic inactivation of the transcription factor TIF-IA leads to nucleolar disruption, cell cycle arrest, and p53-mediated apoptosis. Molec. Cell 19: 77-87, 2005. -
限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.
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储存条件
- 4 °C,-20 °C
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储存方法
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At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.
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- RRN3 (RRN3 RNA Polymerase I Transcription Factor (RRN3))
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别名
- RRN3
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背景
- RNA polymerase I-specific transcription initiation factor RRN3 is an enzyme that in humans is encoded by the RRN3 gene. This gene encodes a member of the cytochrome P450 superfamily of enzymes, which participate in drug metabolism and the synthesis of cholesterol, steroids and other lipids. This enzyme hydroxylates testosterone and dehydroepiandrosterone 3-sulphate, which is involved in the formation of estriol during pregnancy. This gene is part of a cluster of related genes on chromosome 7q21.1.
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分子量
- 74 kDa
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基因ID
- 54700
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途径
- Negative Regulation of intrinsic apoptotic Signaling
抗原
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