IFI16 抗体 (AA 183-743)
Quick Overview for IFI16 抗体 (AA 183-743) (ABIN7600373)
抗原
See all IFI16 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 183-743
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原理
- Anti-IFI16 Antibody Picoband® (monoclonal, 2I3D7)
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交叉反应 （详细）
- No cross-reactivity with other proteins.
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产品特性
- Anti-IFI16 Antibody Picoband® (monoclonal, 2I3D7) (ABIN7600373). Tested in Flow Cytometry, IF, ICC, WB applications. This antibody reacts with Human. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
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纯化方法
- Immunogen affinity purified.
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免疫原
- E.coli-derived human IFI16 recombinant protein (Position: E183-K743).
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亚型
- IgG2b
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anti-Interferon, gamma-Inducible Protein 16 (IFI16) (AA 465-671) antibody
IFI16 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Interferon, gamma-Inducible Protein 16 (IFI16) antibodyIFI16 适用: 人, 小鼠, 大鼠 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Interferon, gamma-Inducible Protein 16 (IFI16) (AA 630-729) antibodyIFI16 适用: 人 WB, ELISA, IF, IHC (p) 宿主: 小鼠 Monoclonal 2E3 unconjugated
anti-Interferon, gamma-Inducible Protein 16 (IFI16) (AA 630-729) antibodyIFI16 适用: 人 WB, ELISA, IHC (p) 宿主: 小鼠 Monoclonal 1B4 unconjugated
anti-Interferon, gamma-Inducible Protein 16 (IFI16) (AA 1-300) antibodyIFI16 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Interferon, gamma-Inducible Protein 16 (IFI16) (AA 1-729) antibodyIFI16 适用: 人 WB, IF 宿主: 小鼠 Polyclonal unconjugated
anti-Interferon, gamma-Inducible Protein 16 (IFI16) (AA 1-729) antibodyIFI16 适用: 人 WB, IP 宿主: 兔 Polyclonal unconjugated
anti-Interferon, gamma-Inducible Protein 16 (IFI16) (C-Term) antibodyIFI16 适用: 人 WB, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Interferon, gamma-Inducible Protein 16 (IFI16) (AA 201-350) antibodyIFI16 适用: 人 WB, ELISA, IF (cc), IF (p), IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Interferon, gamma-Inducible Protein 16 (IFI16) (AA 630-729) antibodyIFI16 适用: 人 WB, ELISA 宿主: 小鼠 Polyclonal unconjugated
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应用备注
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Western blot, 0.25-0.5 μg/mL, Human
Immunocytochemistry/Immunofluorescence, 5 μg/mL, Human
Flow Cytometry (Fixed), 1-3 μg/1x106 cells, Human
1. Choubey, D., Snoddy, J., Chaturvedi, V., Toniato, E., Opdenakker, G., Thakur, A., Samanta, H., Engel, D. A., Lengyel, P. Interferons as gene activators: indications for repeated gene duplication during the evolution of a cluster of interferon-activatable genes on murine chromosome 1. J. Biol. Chem. 264: 17182-17189, 1989. 2. Kerur, N., Veettil, M. V., Sharma-Walia, N., Bottero, V., Sadagopan, S., Otageri, P., Chandran, B. IFI16 acts as a nuclear pathogen sensor to induce the inflammasome in response to Kaposi sarcoma-associated herpesvirus infection. Cell Host Microbe 9: 363-375, 2011. 3. Kingsmore, S. F., Snoddy, J., Choubey, D., Lengyel, P., Seldin, M. F. Physical mapping of a family of interferon-activated genes, serum amyloid P-component, and alpha-spectrin on mouse chromosome 1. Immunogenetics 30: 169-174, 1989. -
限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl and 0.2 mg Na2HPO4.
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储存条件
- 4 °C,-20 °C
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储存方法
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At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.
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- IFI16 (Interferon, gamma-Inducible Protein 16 (IFI16))
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别名
- IFI16
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背景
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Synonyms: Dihydrofolate reductase, DHFR
Tissue Specificity: Widely expressed in fetal and adult tissues, including throughout the fetal and adult brains and whole blood. Expression is higher in the adult brain than in the fetal brain.
Background: Gamma-interferon-inducible protein Ifi-16 (Ifi-16) also known as interferon-inducible myeloid differentiation transcriptional activator is a protein that in humans is encoded by the IFI16 gene. This gene encodes a member of the HIN-200 (hematopoietic interferon-inducible nuclear antigens with 200 amino acid repeats) family of cytokines. The encoded protein contains domains involved in DNA binding, transcriptional regulation, and protein-protein interactions. The protein localizes to the nucleoplasm and nucleoli, and interacts with p53 and retinoblastoma-1. It modulates p53 function, and inhibits cell growth in the Ras/Raf signaling pathway. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
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分子量
- 98 kDa
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基因ID
- 3428
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UniProt
- Q16666
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途径
- Activation of Innate immune Response, Positive Regulation of Endopeptidase Activity, Autophagy, Inflammasome
抗原
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