Calmegin 抗体 (AA 18-611)
Quick Overview for Calmegin 抗体 (AA 18-611) (ABIN7600354)
抗原
See all Calmegin (CLGN) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 18-611
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原理
- Anti-Calmegin/Clgn Antibody Picoband®
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交叉反应 （详细）
- No cross-reactivity with other proteins.
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产品特性
- Anti-Calmegin/Clgn Antibody Picoband® (ABIN7600354). Tested in ELISA, WB applications. This antibody reacts with Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
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纯化方法
- Immunogen affinity purified.
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免疫原
- E.coli-derived mouse Calmegin/Clgn recombinant protein (Position: N18-D611).
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亚型
- IgG
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anti-Calmegin (CLGN) antibody
CLGN 适用: 人 WB, IHC, IF 宿主: 兔 Monoclonal unconjugated
anti-Calmegin (CLGN) (AA 249-405) antibodyCLGN 适用: 人 WB, ELISA, IHC, ICC, FACS 宿主: 小鼠 Monoclonal 9C8G10 unconjugated
anti-Calmegin (CLGN) (AA 249-405) antibodyCLGN 适用: 人 WB, ELISA, IHC, FACS, IF/ICC 宿主: 小鼠 Monoclonal unconjugated
anti-Calmegin (CLGN) antibodyCLGN 适用: 人 WB, IF 宿主: 兔 Monoclonal unconjugated
anti-Calmegin (CLGN) (AA 200-400) antibodyCLGN 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Calmegin (CLGN) (AA 21-120) antibodyCLGN 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 3B5 unconjugated
anti-Calmegin (CLGN) (AA 51-100) antibodyCLGN 适用: 人, Cow, 犬, 豚鼠, 兔, 猴 WB 宿主: 兔 Polyclonal unconjugated
anti-Calmegin (CLGN) (N-Term) antibodyCLGN 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Calmegin (CLGN) antibodyKD Validated CLGN 适用: 人, 小鼠, 大鼠 WB, IHC, IP, ICC, IF 宿主: 兔 Monoclonal unconjugated Recombinant Antibody
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应用备注
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Western blot, 0.1-0.25 μg/mL, Mouse, Rat
ELISA, 0.1-0.5 μg/mL, -
1. Ikawa, M., Nakanishi, T., Yamada, S., Wada, I., Kominami, K., Tanaka, H., Nozaki, M., Nishimune, Y., Okabe, M. Calmegin is required for fertilin alpha/beta heterodimerization and sperm fertility. Dev. Biol. 240: 254-261, 2001. 2. Ikawa, M., Wada, I., Kominami, K., Watanabe, D., Toshimori, K., Nishimune, Y., Okabe, M. The putative chaperone calmegin is required for sperm fertility. Nature 387: 607-611, 1997. 3. Tanaka, H., Ikawa, M., Tsuchida, J., Nozaki, M., Suzuki, M., Fujiwara, T., Okabe, M., Nishimune, Y. Cloning and characterization of the human calmegin gene encoding putative testis-specific chaperone. Gene 204: 159-163, 1997. -
限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.
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储存条件
- 4 °C,-20 °C
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储存方法
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At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.
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- Calmegin (CLGN)
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别名
- Clgn
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背景
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Synonyms: Transcription factor MafA, Pancreatic beta-cell-specific transcriptional activator, RIPE3b1 factor, V-maf musculoaponeurotic fibrosarcoma oncogene homolog A, MAFA
Tissue Specificity: Preferentially expressed in regulatory T-cells (Tregs).
Background: Calmegin, also known as CLGN, is a protein which in humans is encoded by the CLGN gene. This gene belongs to the calreticulin family, which includes calreticulin, calnexin, and calmegin, and encodes a calcium-binding molecular chaperone specifically expressed in pachytene stage male germ cells. It is required for the proper folding of newly synthesized membrane proteins in the endoplasmic reticulum including those critical for sperm migration from the uterus into the oviduct and sperm adhesion to and penetration of the zona pellucida. This gene plays a key role in spermatogenesis and male infertility. Alternative splice variants exist for this gene.
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分子量
- 95 kDa
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基因ID
- 12745
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UniProt
- P52194
抗原
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