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RFTN1 抗体 (AA 18-437)

RFTN1 适用: 人 WB, ELISA, ICC, IF, FACS 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN7600344
发货至: 中国
  • 抗原 See all RFTN1 抗体
    RFTN1 (Raftlin, Lipid Raft Linker 1 (RFTN1))
    抗原表位
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 18-437
    适用
    • 6
    • 4
    • 2
    • 1
    宿主
    • 7
    克隆类型
    • 7
    多克隆
    标记
    • 7
    This RFTN1 antibody is un-conjugated
    应用范围
    • 7
    • 3
    • 2
    • 2
    • 2
    • 1
    Western Blotting (WB), ELISA, Immunocytochemistry (ICC), Immunofluorescence (IF), Flow Cytometry (FACS)
    原理
    Anti-RFTN1 Antibody Picoband®
    交叉反应 (详细)
    No cross-reactivity with other proteins.
    产品特性
    Anti-RFTN1 Antibody Picoband® (ABIN7600344). Tested in ELISA, Flow Cytometry, IF, ICC, WB applications. This antibody reacts with Human. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
    纯化方法
    Immunogen affinity purified.
    免疫原
    E.coli-derived human RFTN1 recombinant protein (Position: N18-K437).
    亚型
    IgG
    Top Product
    Discover our top product RFTN1 Primary Antibody
  • 应用备注
    Western blot, 0.25-0.5 μg/mL, Human
    Immunocytochemistry/Immunofluorescence, 5 μg/mL, Human
    Flow Cytometry (Fixed), 1-3 μg/1x106 cells, Human
    ELISA, 0.1-0.5 μg/mL, -
    1. Saeki, K., Miura, Y., Aki, D., Kurosaki, T., Yoshimura, A. The B cell-specific major raft protein, Raftlin, is necessary for the integrity of lipid raft and BCR signal transduction. EMBO J. 22: 3015-3026, 2003. 2. Tatematsu, M., Yoshida, R., Morioka, Y., Ishii, N., Funami, K., Watanabe, A., Saeki, K., Seya, T., Matsumoto, M. Raftlin controls lipopolysaccharide-induced TLR4 internalization and TICAM-1 signaling in a cell type-specific manner. J. Immun. 196: 3865-3876, 2016. 3. Watanabe, A., Tatematsu, M., Saeki, K., Shibata, S., Shime, H., Yoshimura, A., Obuse, C., Seya, T., Matsumoto, M. Raftlin is involved in the nucleocapture complex to induce poly(I:C)-mediated TLR3 activation. J. Biol. Chem. 286: 10702-10711, 2011.
    限制
    仅限研究用
  • 状态
    Lyophilized
    溶解方式
    Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
    浓度
    500 μg/mL
    缓冲液
    Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.
    储存条件
    4 °C,-20 °C
    储存方法
    At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
    It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.
  • 抗原
    RFTN1 (Raftlin, Lipid Raft Linker 1 (RFTN1))
    别名
    RFTN1 (RFTN1 产品)
    背景

    Synonyms: Interleukin-17B, IL-17B, Cytokine CX1, Cytokine-like protein ZCYTO7, Neuronal interleukin-17-related factor, Il17b, Nirf, Zcyto7

    Tissue Specificity: Expressed in adult pancreas, small intestine, stomach, spinal cord and testis. Less pronounced expression in prostate, colon mucosal lining, and ovary.

    Background: Enables double-stranded RNA binding activity. Involved in B cell receptor signaling pathway, membrane raft assembly, and positive regulation of growth rate. Acts upstream of or within dsRNA transport, response to exogenous dsRNA, and toll-like receptor 3 signaling pathway. Located in endosome, membrane raft, and plasma membrane. Part of protein-containing complex.

    分子量
    70 kDa
    基因ID
    23180
    UniProt
    Q14699
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