RFTN1 抗体 (AA 18-437)
Quick Overview for RFTN1 抗体 (AA 18-437) (ABIN7600344)
抗原
See all RFTN1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 18-437
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原理
- Anti-RFTN1 Antibody Picoband®
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交叉反应 （详细）
- No cross-reactivity with other proteins.
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产品特性
- Anti-RFTN1 Antibody Picoband® (ABIN7600344). Tested in ELISA, Flow Cytometry, IF, ICC, WB applications. This antibody reacts with Human. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
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纯化方法
- Immunogen affinity purified.
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免疫原
- E.coli-derived human RFTN1 recombinant protein (Position: N18-K437).
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亚型
- IgG
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anti-Raftlin, Lipid Raft Linker 1 (RFTN1) (AA 288-520) antibody
RFTN1 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Raftlin, Lipid Raft Linker 1 (RFTN1) (AA 207-451) antibodyRFTN1 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Raftlin, Lipid Raft Linker 1 (RFTN1) (Internal Region) antibodyRFTN1 适用: 人, 小鼠 WB, ELISA, ICC, IF 宿主: 兔 Polyclonal unconjugated
anti-Raftlin, Lipid Raft Linker 1 (RFTN1) (C-Term) antibodyRFTN1 适用: 人 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Raftlin, Lipid Raft Linker 1 (RFTN1) (AA 169-198) antibodyRFTN1 适用: 人 WB 宿主: 兔 Polyclonal RB41751 unconjugated
anti-Raftlin, Lipid Raft Linker 1 (RFTN1) (C-Term) antibodyRFTN1 适用: 人, 小鼠, 大鼠, 猴 WB 宿主: 兔 Polyclonal unconjugated
anti-Raftlin, Lipid Raft Linker 1 (RFTN1) antibodyRFTN1 适用: 人, 小鼠, 大鼠 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
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Western blot, 0.25-0.5 μg/mL, Human
Immunocytochemistry/Immunofluorescence, 5 μg/mL, Human
Flow Cytometry (Fixed), 1-3 μg/1x106 cells, Human
ELISA, 0.1-0.5 μg/mL, -
1. Saeki, K., Miura, Y., Aki, D., Kurosaki, T., Yoshimura, A. The B cell-specific major raft protein, Raftlin, is necessary for the integrity of lipid raft and BCR signal transduction. EMBO J. 22: 3015-3026, 2003. 2. Tatematsu, M., Yoshida, R., Morioka, Y., Ishii, N., Funami, K., Watanabe, A., Saeki, K., Seya, T., Matsumoto, M. Raftlin controls lipopolysaccharide-induced TLR4 internalization and TICAM-1 signaling in a cell type-specific manner. J. Immun. 196: 3865-3876, 2016. 3. Watanabe, A., Tatematsu, M., Saeki, K., Shibata, S., Shime, H., Yoshimura, A., Obuse, C., Seya, T., Matsumoto, M. Raftlin is involved in the nucleocapture complex to induce poly(I:C)-mediated TLR3 activation. J. Biol. Chem. 286: 10702-10711, 2011. -
限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.
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储存条件
- 4 °C,-20 °C
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储存方法
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At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.
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- RFTN1 (Raftlin, Lipid Raft Linker 1 (RFTN1))
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别名
- RFTN1
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背景
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Synonyms: Interleukin-17B, IL-17B, Cytokine CX1, Cytokine-like protein ZCYTO7, Neuronal interleukin-17-related factor, Il17b, Nirf, Zcyto7
Tissue Specificity: Expressed in adult pancreas, small intestine, stomach, spinal cord and testis. Less pronounced expression in prostate, colon mucosal lining, and ovary.
Background: Enables double-stranded RNA binding activity. Involved in B cell receptor signaling pathway, membrane raft assembly, and positive regulation of growth rate. Acts upstream of or within dsRNA transport, response to exogenous dsRNA, and toll-like receptor 3 signaling pathway. Located in endosome, membrane raft, and plasma membrane. Part of protein-containing complex.
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分子量
- 70 kDa
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基因ID
- 23180
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UniProt
- Q14699
抗原
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