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RFTN1 抗体 (Internal Region)

RFTN1 适用: 人, 小鼠 WB, ELISA, ICC, IF 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN6259466
发货至: 中国
  • 抗原 See all RFTN1 抗体
    RFTN1 (Raftlin, Lipid Raft Linker 1 (RFTN1))
    抗原表位
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Internal Region
    适用
    • 8
    • 4
    • 3
    • 1
    人, 小鼠
    宿主
    • 9
    克隆类型
    • 9
    多克隆
    标记
    • 9
    This RFTN1 antibody is un-conjugated
    应用范围
    • 9
    • 3
    • 2
    • 2
    • 2
    Western Blotting (WB), ELISA, Immunocytochemistry (ICC), Immunofluorescence (IF)
    特异性
    RFTN1 Antibody detects endogenous levels of total RFTN1.
    预测反应
    Horse,Dog
    纯化方法
    The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
    免疫原
    A synthesized peptide derived from human RFTN1, corresponding to a region within the internal amino acids.
    亚型
    IgG
    Top Product
    Discover our top product RFTN1 Primary Antibody
  • 应用备注
    WB 1:500-1:1000, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 mg/mL
    缓冲液
    Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    Store at -20 °C. Stable for 12 months from date of receipt.
    有效期
    12 months
  • 抗原
    RFTN1 (Raftlin, Lipid Raft Linker 1 (RFTN1))
    别名
    RFTN1 (RFTN1 产品)
    别名
    RAFTLIN antibody, RGD1310777 antibody, RGD1563347 antibody, 2310015n21rik antibody, mig2 antibody, pig9 antibody, pib10 antibody, raftlin antibody, DKFZp459B0154 antibody, 2310015N21Rik antibody, AI853526 antibody, PIB10 antibody, PIG9 antibody, raftlin, lipid raft linker 1 antibody, raftlin lipid raft linker 1 antibody, RFTN1 antibody, Rftn1 antibody, rftn1 antibody
    背景

    Description: Involved in protein trafficking via association with clathrin and AP2 complex (PubMed:27022195, PubMed:21266579). Upon bacterial lipopolysaccharide stimulation, mediates internalization of TLR4 to endosomes in dendritic cells and macrophages, and internalization of poly(I:C) to TLR3-positive endosomes in myeloid dendritic cells and epithelial cells, resulting in activation of TICAM1-mediated signaling and subsequent IFNB1 production (PubMed:27022195, PubMed:21266579). Involved in T-cell antigen receptor-mediated signaling by regulating tyrosine kinase LCK localization, T-cell dependent antibody production and cytokine secretion (By similarity). May regulate B-cell antigen receptor-mediated signaling (PubMed:12805216). May play a pivotal role in the formation and/or maintenance of lipid rafts (PubMed:12805216).

    Gene: RFTN1

    分子量
    63 kDa
    基因ID
    23180
    UniProt
    Q14699
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