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ACE2 抗体 (AA 18-314)

Name: ACE2 抗体 (AA 18-314)
SKU: ABIN7600328
Availability: OutOfStock

This anti-ACE2 antibody is a 兔多克隆 antibody detecting ACE2 in WB, ELISA 和 FACS. Suitable for 人.

产品编号 ABIN7600328

发货至: 中国

Quick Overview for ACE2 抗体 (AA 18-314) (ABIN7600328)

抗原

See all ACE2 抗体

ACE2 (Angiotensin I Converting Enzyme 2 (ACE2))

适用

人

宿主

兔

克隆类型

多克隆

标记

This ACE2 antibody is un-conjugated

应用范围

Western Blotting (WB), ELISA, Flow Cytometry (FACS)

Discover our top product ACE2 Primary Antibody

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AA 18-314

原理

Anti-ACE2 Antibody Picoband®

产品特性

Anti-ACE2 Antibody Picoband® (ABIN7600328). Tested in WB, Flow Cytometry, ELISA applications. This antibody reacts with Human. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

纯化方法

Immunogen affinity purified.

免疫原

E.coli-derived human ACE2 recombinant protein (Position: Q18-F314). Human ACE2 shares 80.5% and 80.8% amino acid (aa) sequence identity with mouse and rat ACE2, respectively.
anti-Angiotensin I Converting Enzyme 2 (ACE2) (AA 601-700) antibody
ACE2 适用: 人, 小鼠, 大鼠 WB, ELISA, FACS, ICC, IHC (p), IF (cc), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated

anti-Angiotensin I Converting Enzyme 2 (ACE2) antibody
ACE2 适用: 人 WB, ELISA, FACS 宿主: 小鼠 Monoclonal AC18F unconjugated

anti-Angiotensin I Converting Enzyme 2 (ACE2) (AA 18-250) antibody
ACE2 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated

anti-Angiotensin I Converting Enzyme 2 (ACE2) (AA 93-464) antibody
ACE2 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated

anti-Angiotensin I Converting Enzyme 2 (ACE2) (AA 392-739) antibody
ACE2 适用: 大鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated

anti-Angiotensin I Converting Enzyme 2 (ACE2) (N-Term) antibody
Verified ACE2 适用: 人 WB, IHC, ELISA, FACS 宿主: 山羊 Polyclonal unconjugated

anti-Angiotensin I Converting Enzyme 2 (ACE2) (AA 773-805), (C-Term) antibody
ACE2 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal RB4819 unconjugated

anti-Angiotensin I Converting Enzyme 2 (ACE2) (AA 140-172) antibody
ACE2 适用: 人 WB, IHC, ELISA, FACS 宿主: 兔 Polyclonal unconjugated

anti-Angiotensin I Converting Enzyme 2 (ACE2) (AA 59-90) antibody
ACE2 适用: 人 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated

anti-Angiotensin I Converting Enzyme 2 (ACE2) (AA 351-450) antibody
ACE2 适用: 人, 小鼠 WB, ELISA, ICC, IHC (p), IF (cc), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated

应用备注

Western blot, 0.25-0.5 μg/mL, Human
Flow Cytometry (Fixed), 1-3 μg/1x10⁶ cells, Human
ELISA, 0.1-0.5 μg/mL, -
1. Boehm, M., Nabel, E. G. Angiotensin-converting enzyme 2--a new cardiac regulator. New Eng. J. Med. 347: 1795-1797, 2002. 2. Crackower, M. A., Sarao, R., Oudit, G. Y., Yagil, C., Kozieradzki, I., Scanga, S. E., Oliveira-dos-Santos, A. J., da Costa, J., Zhang, L., Pei, Y., Scholey, J., Ferrario, C. M., Manoukian, A. S., Chappell, M. C., Backx, P. H., Yagil, Y., Penninger, J. M. Angiotensin-converting enzyme 2 is an essential regulator of heart function. Nature 417: 822-828, 2002. 3. Gurley, S. B., Allred, A., Le, T. H., Griffiths, R., Mao, L., Philip, N., Haystead, T. A., Donoghue, M., Breitbart, R. E., Acton, S. L., Rockman, H. A., Coffman, T. M. Altered blood pressure responses and normal cardiac phenotype in ACE2-null mice. J. Clin. Invest. 116: 2218-2225, 2006.

限制

仅限研究用
状态

Lyophilized

溶解方式

Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

浓度

500 μg/mL

缓冲液

Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

储存条件

4 °C,-20 °C

储存方法

At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.
抗原

ACE2 (Angiotensin I Converting Enzyme 2 (ACE2))

别名

ACE2

背景

The protein encoded by this gene belongs to the angiotensin-converting enzyme family of dipeptidyl carboxydipeptidases and has considerable homology to human angiotensin 1 converting enzyme. This secreted protein catalyzes the cleavage of angiotensin I into angiotensin 1-9, and angiotensin II into the vasodilator angiotensin 1-7. ACE2 is known to be expressed in various human organs, and its organ- and cell-specific expression suggests that it may play a role in the regulation of cardiovascular and renal function, as well as fertility. In addition, the encoded protein is a functional receptor for the spike glycoprotein of the human coronavirus HCoV-NL63 and the human severe acute respiratory syndrome coronaviruses, SARS-CoV and SARS-CoV-2, the latter is the causative agent of coronavirus disease-2019 (COVID-19). Multiple splice variants have been found for this gene and the dACE2 (or MIRb-ACE2) splice variant has been found to be interferon inducible.

分子量

120 kDa

基因ID

59272

途径

ACE Inhibitor Pathway, Peptide Hormone Metabolism, Regulation of Systemic Arterial Blood Pressure by Hormones, Feeding Behaviour