IL-21 抗体 (AA 18-146)
Quick Overview for IL-21 抗体 (AA 18-146) (ABIN7600316)
抗原
See all IL-21 (IL21) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 18-146
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原理
- Anti-IL-21/Il21 Antibody
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交叉反应 （详细）
- No cross-reactivity with other proteins
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产品特性
- Anti-IL-21/Il21 Antibody Picoband® (ABIN7600316). Tested in ELISA, IHC applications. This antibody reacts with Mouse, Rat.
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纯化方法
- Immunogen affinity purified.
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免疫原
- E.coli-derived mouse IL-21/Il21 recombinant protein (Position: H18-S146).
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亚型
- IgG
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anti-Interleukin 21 (IL21) (AA 25-162) antibody
IL21 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Interleukin 21 (IL21) (AA 1-162) antibodyIL21 适用: 人 WB, PLA 宿主: 兔 Polyclonal unconjugated
anti-Interleukin 21 (IL21) (AA 65-155) antibodyIL21 适用: 人, 小鼠 WB, ELISA, IF (p), IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Interleukin 21 (IL21) (AA 25-146) antibodyIL21 适用: 小鼠 WB, IHC, ICC, IP 宿主: 兔 Polyclonal unconjugated
anti-Interleukin 21 (IL21) (AA 25-162) antibodyIL21 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Interleukin 21 (IL21) (AA 23-155) antibodyIL21 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Interleukin 21 (IL21) antibodyIL21 适用: 人, 大鼠 WB, IHC, IF, IC 宿主: 兔 Polyclonal unconjugated
anti-Interleukin 21 (IL21) (AA 1-146) antibodyIL21 适用: 大鼠 WB, IHC, ICC, IP 宿主: 兔 Polyclonal unconjugated
anti-Interleukin 21 (IL21) (AA 63-162) antibodyIL21 适用: 人 WB, ELISA 宿主: 小鼠 Polyclonal unconjugated
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应用备注
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Immunohistochemistry (Paraffin-embedded Section), 2-5 μg/mL, Mouse, Rat
ELISA, 0.1-0.5 μg/mL, -
1. Berglund, L. J., Avery, D. T., Ma, C. S., Moens, L., Deenick, E. K., Bustamante, J., Boisson-Dupuis, S., Wong, M., Adelstein, S., Arkwright, P. D., Bacchetta, R., Bezrodnik, L., and 12 others. IL-21 signalling via STAT3 primes human naive B cells to respond to IL-2 to enhance their differentiation into plasmablasts. Blood 122: 3940-3950, 2013. 2. Brandt, K., Singh, P. B., Bulfone-Paus, S., Ruckert, R. Interleukin-21: a new modulator of immunity, infection, and cancer. Cytokine Growth Factor Rev. 18: 223-232, 2007. 3. Brodeur, T. Y., Robidoux, T. E., Weinstein, J. S., Craft, J., Swain, S. L., Marshak-Rothstein, A. IL-21 promotes pulmonary fibrosis through the induction of profibrotic CD8+ T cells. J. Immun. 195: 5251-5260, 2015. -
限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.005 mg Sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
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Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
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- IL-21 (IL21) (Interleukin 21 (IL21))
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别名
- Il21
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背景
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Synonyms: Beta-2-microglobulin, B2m
Tissue Specificity: Detected in lung, spleen, uterus, vagina and epididymis. .
Background: Interleukin 21 (IL-21) is a protein that in humans is encoded by the IL21 gene. This gene encodes a member of the common-gamma chain family of cytokines with immunoregulatory activity. The encoded protein plays a role in both the innate and adaptive immune responses by inducing the differentiation, proliferation and activity of multiple target cells including macrophages, natural killer cells, B cells and cytotoxic T cells. Dysregulation of this gene plays a role in multiple immune-mediated diseases including lupus, psoriasis and chronic inflammatory diseases. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.
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分子量
- 65-80 kDa
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基因ID
- 60505
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途径
- JAK/STAT Signaling, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response
抗原
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