IRF1 抗体 (AA 170-315)
Quick Overview for IRF1 抗体 (AA 170-315) (ABIN7600281)
抗原
See all IRF1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 170-315
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原理
- Anti-IRF1 Antibody Picoband®
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交叉反应 （详细）
- No cross-reactivity with other proteins.
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产品特性
- Anti-IRF1 Antibody Picoband® (ABIN7600281). Tested in ELISA, Flow Cytometry, IF, IHC, ICC, WB applications. This antibody reacts with Human, Mouse. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
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纯化方法
- Immunogen affinity purified.
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免疫原
- E.coli-derived human IRF1 recombinant protein (Position: M170-L315).
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亚型
- IgG
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anti-Interferon Regulatory Factor 1 (IRF1) (AA 44-319) antibody
IRF1 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Interferon Regulatory Factor 1 (IRF1) antibodyIRF1 适用: 人, 小鼠, 大鼠 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Interferon Regulatory Factor 1 (IRF1) (AA 216-325) antibodyIRF1 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 2E4 unconjugated
anti-Interferon Regulatory Factor 1 (IRF1) antibodyIRF1 适用: 人, 小鼠 WB, IF (p), IHC (p), FACS, IF (cc) 宿主: 兔 Monoclonal 3G7 unconjugated
anti-Interferon Regulatory Factor 1 (IRF1) (AA 1-325) antibodyIRF1 适用: 人 WB, IF 宿主: 小鼠 Polyclonal unconjugated
anti-Interferon Regulatory Factor 1 (IRF1) (N-Term) antibodyIRF1 适用: 人, 小鼠, 大鼠, 犬, Cow, 兔, 豚鼠, 绵羊, 马, 斑马鱼 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Interferon Regulatory Factor 1 (IRF1) antibodyIRF1 适用: 人, 小鼠, 大鼠 WB, IF (p), IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Interferon Regulatory Factor 1 (IRF1) (Internal Region) antibodyIRF1 适用: 人 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Interferon Regulatory Factor 1 (IRF1) (AA 11-276) antibodyIRF1 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Interferon Regulatory Factor 1 (IRF1) (AA 1-325) antibodyIRF1 适用: 人 IP 宿主: 兔 Polyclonal unconjugated
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应用备注
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Western blot, 0.25-0.5 μg/mL, Human
Immunohistochemistry (Paraffin-embedded Section), 0.5-1 μg/mL, Human, Mouse
Immunocytochemistry/Immunofluorescence, 2 μg/mL, Human
Flow Cytometry (Fixed), 1-3 μg/1x106 cells, Human
ELISA, 0.1-0.5 μg/mL, -
1. Harada, H., Willison, K., Sakakibara, J., Miyamoto, M., Fujita, T., Taniguchi, T. Absence of the type I IFN system in EC cells: transcriptional activator (IRF-1) and repressor (IRF-2) genes are developmentally regulated. Cell 63: 303-312, 1990. 2. Itoh, S., Harada, H., Nakamura, Y., White, R., Taniguchi, T. Assignment of the human interferon regulatory factor-1 (IRF1) gene to chromosome 5q23-q31. Genomics 10: 1097-1099, 1991. 3. Ko, J., Gendron-Fitzpatrick, A., Splitter, G. A. Susceptibility of IFN regulatory factor-1 and IFN consensus sequence binding protein-deficient mice to brucellosis. J. Immun. 168: 2433-2440, 2002. -
限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.01 mg Sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
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Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
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- IRF1 (Interferon Regulatory Factor 1 (IRF1))
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别名
- IRF1
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背景
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Synonyms: Interferon regulatory factor 1, IRF-1, IRF1
Tissue Specificity: Expressed in brain and glioma tissue and glioma cell lines (at protein level). Expressed most highly in tissues that contain a high proportion of epithelial cells, e.g. skin, intestine, lung, and ovary.
Background: Interferon regulatory factor 1, also known as MAR is a protein that in humans is encoded by the IRF1 gene. The IRF1 gene is mapped to chromosome 5q31.1 by pulsed-field gel electrophoresis. IRF1 encodes interferon regulatory factor 1, a member of the interferon regulatory transcription factor (IRF) family. IRF1 serves as an activator of interferons alpha and beta transcription, and in mouse it has been shown to be required for double-stranded RNA induction of these genes. IRF1 also functions as a transcription activator of genes induced by interferons alpha, beta, and gamma. Further, IRF1 has been shown to play roles in regulating apoptosis and tumor-suppressoion.?
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分子量
- 48-50 kDa
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基因ID
- 3659
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UniProt
- P10914
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途径
- Interferon-gamma Pathway, Response to Growth Hormone Stimulus, Positive Regulation of Immune Effector Process, Hepatitis C, Autophagy
抗原
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