GFR 抗体 (AA 164-574)
Quick Overview for GFR 抗体 (AA 164-574) (ABIN7600218)
抗原
See all GFR (RAPGEF5) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 164-574
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原理
- Anti-RAPGEF5 Antibody Picoband®
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交叉反应 （详细）
- No cross reactivity with other proteins.
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产品特性
- Anti-RAPGEF5 Antibody Picoband® (ABIN7600218). Tested in WB, ELISA applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
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纯化方法
- Immunogen affinity purified.
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免疫原
- E.coli-derived human RAPGEF5 recombinant protein (Position: E164-H574). Human RAPGEF5 shares 95.6% and 96.4% amino acid (aa) sequence identity with mouse and rat RAPGEF5, respectively.
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亚型
- IgG
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anti-Rap Guanine Nucleotide Exchange Factor (GEF) 5 (RAPGEF5) antibody
RAPGEF5 适用: 小鼠, 大鼠 IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Rap Guanine Nucleotide Exchange Factor (GEF) 5 (RAPGEF5) (AA 201-444) antibodyRAPGEF5 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Rap Guanine Nucleotide Exchange Factor (GEF) 5 (RAPGEF5) (AA 1-444) antibodyRAPGEF5 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 2E4 unconjugated
anti-Rap Guanine Nucleotide Exchange Factor (GEF) 5 (RAPGEF5) (AA 1-444) antibodyRAPGEF5 适用: 人 WB, IF 宿主: 小鼠 Polyclonal unconjugated
anti-Rap Guanine Nucleotide Exchange Factor (GEF) 5 (RAPGEF5) (C-Term) antibodyRAPGEF5 适用: 人, 小鼠, 大鼠 WB, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Rap Guanine Nucleotide Exchange Factor (GEF) 5 (RAPGEF5) (N-Term) antibodyRAPGEF5 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
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Western blot, 0.25-0.5 μg/mL, Human, Mouse, Rat
ELISA, 0.1-0.5 μg/mL, -
1. Ichiba, T., Hoshi, Y., Eto, Y., Tajima, N., Kuraishi, Y. Characterization of GFR, a novel guanine nucleotide exchange factor for Rap1. FEBS Lett. 457: 85-89, 1999. 2. Nagase, T., Seki, N., Ishikawa, K., Ohira, M., Kawarabayasi, Y., Ohara, O., Tanaka, A., Kotani, H., Miyajima, N., Nomura, N. Prediction of the coding sequences of unidentified human genes. VI. The coding sequences of 80 new genes (KIAA0201-KIAA0280) deduced by analysis of cDNA clones from cell line KG-1 and brain. DNA Res. 3: 321-329, 1996. 3. Rebhun, J. F., Castro, A. F., Quilliam, L. A. Identification of guanine nucleotide exchange factors (GEFs) for the Rap1 GTPase: regulation of MR-GEF by M-Ras-GTP interaction. J. Biol. Chem. 275: 34901-34908, 2000. -
限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.
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储存条件
- 4 °C,-20 °C
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储存方法
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At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.
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- GFR (RAPGEF5) (Rap Guanine Nucleotide Exchange Factor (GEF) 5 (RAPGEF5))
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别名
- RAPGEF5
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背景
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Synonyms: 70 kDa ribosomal protein S6 kinase 1 antibody, KS6B1_HUMAN antibody, p70 alpha antibody, P70 beta 1 antibody, p70 ribosomal S6 kinase alpha antibody, p70 ribosomal S6 kinase beta 1 antibody, p70 S6 kinase alpha antibody, P70 S6 Kinase antibody, p70 S6 kinase alpha 1 antibody, p70 S6 kinase alpha 2 antibody, p70 S6K antibody, p70 S6K-alpha antibody, p70 S6KA antibody, p70(S6K) alpha antibody, p70(S6K)-alpha antibody, p70-alpha antibody, p70-S6K 1 antibody, p70-S6K antibody, P70S6K antibody, P70S6K1 antibody, p70S6Kb antibody, PS6K antibody, Ribosomal protein S6 kinase 70 kDa polypeptide 1 antibody, Ribosomal protein S6 kinase beta 1 antibody, Ribosomal protein S6 kinase beta-1 antibody, Ribosomal protein S6 kinase I antibody, RPS6KB1 antibody, S6K antibody, S6K-beta-1 antibody, S6K1 antibody, Serine/threonine kinase 14 alpha antibody, Serine/threonine-protein kinase 14A antibody, STK14A antibody
Tissue Specificity: Expressed in all tissues.
Background: Rap guanine nucleotide exchange factor 5 is a protein that in humans is encoded by the RAPGEF5 gene. Members of the RAS subfamily of GTPases function in signal transduction as GTP/GDP-regulated switches that cycle between inactive GDP- and active GTP-bound states. Guanine nucleotide exchange factors (GEFs), such as RAPGEF5, serve as RAS activators by promoting acquisition of GTP to maintain the active GTP-bound state and are the key link between cell surface receptors and RAS activation.
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分子量
- 75 kDa
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基因ID
- 9771
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UniProt
- Q92565
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途径
- RTK signaling, Neurotrophin Signaling Pathway, Hepatitis C
抗原
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