ASIC1 抗体 (AA 163-528)
Quick Overview for ASIC1 抗体 (AA 163-528) (ABIN7600214)
抗原
See all ASIC1 (ACCN2) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 163-528
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原理
- Anti-ASIC1 Antibody Picoband®
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交叉反应 （详细）
- No cross-reactivity with other proteins.
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产品特性
- Anti-ASIC1 Antibody Picoband® (ABIN7600214). Tested in ELISA, WB applications. This antibody reacts with Human. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
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纯化方法
- Immunogen affinity purified.
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免疫原
- E.coli-derived human ASIC1 recombinant protein (Position: H163-C528).
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亚型
- IgG
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anti-Amiloride-Sensitive Cation Channel 2, Neuronal (ACCN2) (N-Term) antibody
ACCN2 适用: 人, 小鼠, 大鼠, Cow, 犬, 豚鼠, 马, 兔 WB 宿主: 兔 Polyclonal unconjugated
anti-Amiloride-Sensitive Cation Channel 2, Neuronal (ACCN2) (C-Term) antibodyVerified ACCN2 适用: 人, 小鼠 WB, IHC, ELISA 宿主: 山羊 Polyclonal unconjugated
anti-Amiloride-Sensitive Cation Channel 2, Neuronal (ACCN2) (Extracellular Domain) antibodyACCN2 适用: 大鼠 WB, IHC 宿主: 绵羊 Polyclonal unconjugated
anti-Amiloride-Sensitive Cation Channel 2, Neuronal (ACCN2) (AA 460-526) antibodyACCN2 适用: 小鼠 WB, IHC, IF, ICC 宿主: 小鼠 Monoclonal S271-44 unconjugated
anti-Amiloride-Sensitive Cation Channel 2, Neuronal (ACCN2) (AA 460-526) antibody (HRP)ACCN2 适用: 小鼠 WB, IHC, IF, ICC 宿主: 小鼠 Monoclonal S271-44 HRP
anti-Amiloride-Sensitive Cation Channel 2, Neuronal (ACCN2) (AA 460-526) antibody (FITC)ACCN2 适用: 小鼠 WB, IHC, IF, ICC 宿主: 小鼠 Monoclonal S271-44 FITC
anti-Amiloride-Sensitive Cation Channel 2, Neuronal (ACCN2) (AA 460-526) antibody (Biotin)ACCN2 适用: 小鼠 WB, IHC, IF, ICC 宿主: 小鼠 Monoclonal S271-44 Biotin
anti-Amiloride-Sensitive Cation Channel 2, Neuronal (ACCN2) (AA 460-526) antibody (PE)ACCN2 适用: 小鼠 WB, IHC, IF, ICC 宿主: 小鼠 Monoclonal S271-44 PE
anti-Amiloride-Sensitive Cation Channel 2, Neuronal (ACCN2) (AA 460-526) antibody (PerCP)ACCN2 适用: 小鼠 WB, IHC, IF, ICC 宿主: 小鼠 Monoclonal S271-44 PerCP
anti-Amiloride-Sensitive Cation Channel 2, Neuronal (ACCN2) (AA 460-526) antibody (APC)ACCN2 适用: 小鼠 WB, IHC, IF, ICC 宿主: 小鼠 Monoclonal S271-44 APC
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应用备注
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Western blot, 0.25-0.5 μg/mL, Human
ELISA, 0.1-0.5 μg/mL, -
1. Hruska-Hageman AM, Wemmie JA, Price MP, Welsh MJ (February 2002). "Interaction of the synaptic protein PICK1 (protein interacting with C kinase 1) with the non-voltage gated sodium channels BNC1 (brain Na+ channel 1) and ASIC (acid-sensing ion channel)". Biochem. J. 361 (Pt 3): 443-50. 2. Hanukoglu I (2017). "ASIC and ENaC type sodium channels: Conformational states and the structures of the ion selectivity filters". FEBS Journal. 284 (4): 525-545. 3. García-Añoveros J, Derfler B, Neville-Golden J, Hyman BT, Corey DP (March 1997). "BNaC1 and BNaC2 constitute a new family of human neuronal sodium channels related to degenerins and epithelial sodium channels". Proc Natl Acad Sci U S A. 94 (4): 1459-64. Bibcode:1997PNAS...94.1459G. -
限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
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Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
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- ASIC1 (ACCN2) (Amiloride-Sensitive Cation Channel 2, Neuronal (ACCN2))
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别名
- ASIC1
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背景
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Synonyms: Acid-sensing ion channel 1, ASIC1,Amiloride-sensitive cation channel 2, neuronal, Brain sodium channel 2, BNaC2, ASIC1, ACCN2, BNAC2
Tissue Specificity: Expressed in most or all neurons.
Background: Acid-sensing ion channel 1 (ASIC1) also known as amiloride-sensitive cation channel 2, neuronal (ACCN2) or brain sodium channel 2 (BNaC2) is a protein that in humans is encoded by the ASIC1 gene. It is mapped to 12q13.12. This gene encodes a member of the acid-sensing ion channel (ASIC) family of proteins, which are part of the degenerin/epithelial sodium channel (DEG/ENaC) superfamily. Members of the ASIC family are sensitive to amiloride and function in neurotransmission. The encoded proteins function in learning, pain transduction, touch sensation, and development of memory and fear. Alternatively spliced transcript variants have been described.
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分子量
- 60 kDa
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基因ID
- 41
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UniProt
- P78348
抗原
-
