Neurofibromin 1 抗体 (AA 160-270)
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Quick Overview for Neurofibromin 1 抗体 (AA 160-270) (ABIN7600197)
抗原
See all Neurofibromin 1 (NF1) 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 160-270
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原理
- Anti-Neurofibromin/NF1 Antibody (monoclonal, 4F8B7)
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交叉反应 (详细)
- No cross-reactivity with other proteins.
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产品特性
- Anti-Neurofibromin/NF1 Antibody.(monoclonal, 4F8B7)-1. Tested in Flow Cytometry, IF, IHC, ICC, WB applications. This antibody reacts with Human, Mouse, Rat.
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纯化方法
- Immunogen affinity purified.
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免疫原
- E.coli-derived human Neurofibromin/NF1 recombinant protein (Position: R160-Q270).
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亚型
- IgG2a
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应用备注
- Western blot, 0.25-0.5 μg/mL, Human, Mouse, Rat Immunohistochemistry(Paraffin-embedded Section), 2-5 μg/mL, Human, Mouse, Rat Immunocytochemistry/Immunofluorescence, 5 μg/mL, Human Flow Cytometry (Fixed), 1-3 μg/1x106 cells, Human
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl and 0.2 mg Na2HPO4.
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储存条件
- 4 °C,-20 °C
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储存方法
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At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing. -
有效期
- 12 months
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- Neurofibromin 1 (NF1)
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别名
- NF1
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背景
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Background: Neurofibromin 1 (NF1) is a gene in humans that is located on chromosome 17. This gene product appears to function as a negative regulator of the ras signal transduction pathway. Mutations in this gene have been linked to neurofibromatosis type 1, juvenile myelomonocytic leukemia and Watson syndrome. The mRNA for this gene is subject to RNA editing (CGA>UGA->Arg1306Term) resulting in premature translation termination. Alternatively spliced transcript variants encoding different isoforms have also been described for this gene.
Gene Full Name: neurofibromin 1
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分子量
- 319 kDa
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基因ID
- 4763
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UniProt
- P21359
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途径
- cAMP Metabolic Process, Regulation of long-term Neuronal Synaptic Plasticity
抗原
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