PAWR 抗体 (AA 160-255)
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北京 101111
Quick Overview for PAWR 抗体 (AA 160-255) (ABIN7600192)
抗原
See all PAWR 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 160-255
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原理
- Anti-PAWR Antibody
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交叉反应 （详细）
- No cross reactivity with other proteins.
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预测反应
- Human PAWR shares 82.3%,81.2% amino acid (aa) sequence identity with mouse,rat PAWR,respectively.
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产品特性
- Anti-PAWR Antibody. Tested in ELISA, IF, ICC, WB, Flow Cytometry applications. This antibody reacts with Human.
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纯化方法
- Immunogen affinity purified.
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免疫原
- E.coli-derived human PAWR recombinant protein (Position: R160-D255). Human PAWR shares 82.3% and 81.2% amino acid (aa) sequence identity with mouse and rat PAWR, respectively.
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亚型
- IgG
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anti-PRKC, Apoptosis, WT1, Regulator (PAWR) antibody
KD Validated PAWR 适用: 人 WB, FACS 宿主: 兔 Monoclonal 24GB5010 unconjugated Recombinant Antibody
anti-PRKC, Apoptosis, WT1, Regulator (PAWR) (AA 13-333) antibodyPAWR 适用: 小鼠, 大鼠 WB, IHC, ELISA, FACS, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-PRKC, Apoptosis, WT1, Regulator (PAWR) (AA 212-261) antibodyPAWR 适用: 人, 犬, 马, 猴, Pig WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-PRKC, Apoptosis, WT1, Regulator (PAWR) (C-Term) antibodyPAWR 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-PRKC, Apoptosis, WT1, Regulator (PAWR) antibodyPAWR 适用: 人 WB, IHC, IF 宿主: 兔 Monoclonal unconjugated
anti-PRKC, Apoptosis, WT1, Regulator (PAWR) (AA 166-215) antibodyPAWR 适用: 人, 小鼠, 大鼠, 犬, 兔, 豚鼠, 猴, Pig WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-PRKC, Apoptosis, WT1, Regulator (PAWR) antibodyPAWR 适用: 人 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-PRKC, Apoptosis, WT1, Regulator (PAWR) (C-Term) antibodyPAWR 适用: 人 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-PRKC, Apoptosis, WT1, Regulator (PAWR) (Middle Region) antibodyPAWR 适用: 人, 小鼠, 大鼠, 犬, 马, 兔 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-PRKC, Apoptosis, WT1, Regulator (PAWR) (Middle Region) antibodyPAWR 适用: 人, 小鼠, 大鼠, 马, 兔, 豚鼠 WB, IHC 宿主: 兔 Polyclonal unconjugated
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应用备注
- Western blot, 0.1-0.25 μg/mL, Human Immunocytochemistry/Immunofluorescence, 5 μg/mL, Human Flow Cytometry (Fixed), 1-3 μg /1x106 cells, Human ELISA, 0.1-0.5 μg/mL, -
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.
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储存条件
- 4 °C,-20 °C
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储存方法
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At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing. -
有效期
- 12 months
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- PAWR (PRKC, Apoptosis, WT1, Regulator (PAWR))
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别名
- PAWR
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背景
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Background: PRKC apoptosis WT1 regulator protein, or Prostate apoptosis response-4, is a tumor-suppressor protein coded for in the human by the PAWR gene, that induces apoptosis in cancer cells, but not in normal cells. This gene encodes a tumor suppressor protein that selectively induces apoptosis in cancer cells through intracellular and extracellular mechanisms. The intracellular mechanism involves the inhibition of pro-survival pathways and the activation of Fas-mediated apoptosis, while the extracellular mechanism involves the binding of a secreted form of this protein to glucose regulated protein 78 (GRP78) on the cell surface, which leads to activation of the extrinsic apoptotic pathway. This gene is located on the unstable human chromosomal 12q21 region and is often deleted or mutated different tumors. The encoded protein also plays an important role in the progression of age-related diseases.
Gene Full Name: pro-apoptotic WT1 regulator
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分子量
- 41 kDa
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基因ID
- 5074
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UniProt
- Q96IZ0
抗原
-
