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SNIP1 抗体 (AA 16-372)

This anti-SNIP1 antibody is a 兔 多克隆 antibody detecting SNIP1 in WB, ELISA 和 FACS. Suitable for 人.
产品编号 ABIN7600177
发货至: 中国

Quick Overview for SNIP1 抗体 (AA 16-372) (ABIN7600177)

抗原

See all SNIP1 抗体
SNIP1 (Smad Nuclear Interacting Protein 1 (SNIP1))

适用

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宿主

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克隆类型

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多克隆

标记

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This SNIP1 antibody is un-conjugated

应用范围

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Western Blotting (WB), ELISA, Flow Cytometry (FACS)
  • 抗原表位

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    AA 16-372

    原理

    Anti-SNIP1 Antibody Picoband®

    交叉反应 (详细)

    No cross-reactivity with other proteins.

    产品特性

    Anti-SNIP1 Antibody Picoband® (ABIN7600177). Tested in ELISA, Flow Cytometry, WB applications. This antibody reacts with Human. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

    纯化方法

    Immunogen affinity purified.

    免疫原

    E.coli-derived human SNIP1 recombinant protein (Position: H16-E372).

    亚型

    IgG
  • 应用备注

    Western blot, 0.25-0.5 μg/mL, Human
    Flow Cytometry (Fixed), 1-3 μg/1x106 cells, Human
    ELISA, 0.1-0.5 μg/mL, -
    1. Fujii, M., Lyakh, L. A., Bracken, C. P., Fukuoka, J., Hayakawa, M., Tsukiyama, T., Soll, S. J., Harris, M., Rocha, S., Roche, K. C., Tominaga, S., Jen, J., Perkins, N. D., Lechleider, R. J., Roberts, A. B. SNIP1 is a candidate modifier of the transcriptional activity of c-Myc on E box-dependent target genes. Molec. Cell 24: 771-783, 2006. 2. Gross, M. B. Personal Communication. Baltimore, Md. 6/8/2017. 3. Kim, R. H., Flanders, K. C., Reffey, S. B., Anderson, L. A., Duckett, C. S., Perkins, N. D., Roberts, A. B. SNIP1 inhibits NF-kappa-B signaling by competing for its binding to the C/H1 domain of CBP/p300 transcriptional co-activators. J. Biol. Chem. 276: 46297-46304, 2001.

    限制

    仅限研究用
  • 状态

    Lyophilized

    溶解方式

    Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

    浓度

    500 μg/mL

    缓冲液

    Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

    储存条件

    4 °C,-20 °C

    储存方法

    At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
    It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.
  • 抗原

    SNIP1 (Smad Nuclear Interacting Protein 1 (SNIP1))

    别名

    SNIP1

    背景

    Synonyms: Tetraspanin-12, Tspan-12, Tetraspan NET-2, Transmembrane 4 superfamily member 12, TSPAN12, NET2, TM4SF12, UNQ774/PRO1568

    Tissue Specificity: Expressed in testis, in Sertoli cells, ejaculated spermatozoa and in seminal fluid (at protein level).

    Background: Smad nuclear-interacting protein 1 is a protein that in humans is encoded by the SNIP1 gene. This gene encodes a protein that contains a coiled-coil motif and C-terminal forkhead-associated (FHA) domain. The encoded protein functions as a transcriptional coactivator that increases c-Myc activity and inhibits transforming growth factor beta (TGF-beta) and nuclear factor kappa-B (NF-kB) signaling. The encoded protein also regulates the stability of cyclin D1 mRNA, and may play a role in cell proliferation and cancer progression. Mutations in this gene are a cause of psychomotor retardation, epilepsy, and craniofacial dysmorphism (PMRED).

    分子量

    46 kDa

    基因ID

    79753

    途径

    SARS-CoV-2 Protein Interactome, The Global Phosphorylation Landscape of SARS-CoV-2 Infection
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