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XIAP 抗体 (AA 15-244)

This anti-XIAP antibody is a 小鼠单克隆 antibody detecting XIAP in WB. Suitable for 人, 小鼠和大鼠.

产品编号 ABIN7600103

发货至: 中国

Quick Overview for XIAP 抗体 (AA 15-244) (ABIN7600103)

抗原

See all XIAP 抗体

XIAP (X-Linked Inhibitor of Apoptosis (XIAP))

适用

人, 小鼠, 大鼠

宿主

小鼠

克隆类型

单克隆

标记

56
5
4
3
2
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1

This XIAP antibody is un-conjugated

应用范围

74
36
30
17
15
14
13
13
12
8
3
2
2

Western Blotting (WB)

克隆位点

3G2G1

Discover our top product XIAP Primary Antibody

抗原表位
16

14

8

5

4

3

2

2

2

2

2

1

1

1

1

1

1

1

1

1

1

1
AA 15-244

原理

Anti-XIAP Antibody Picoband® (monoclonal, 3G2G1)

交叉反应（详细）

No cross-reactivity with other proteins.

产品特性

Anti-XIAP Antibody Picoband® (monoclonal, 3G2G1) (ABIN7600103). Tested in WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

纯化方法

Immunogen affinity purified.

免疫原

E.coli-derived human XIAP recombinant protein (Position: A15-V244). Human XIAP shares 89.4% and 90.7% amino acid (aa) sequence identity with mouse and rat XIAP, respectively.

亚型

IgG1
anti-X-Linked Inhibitor of Apoptosis (XIAP) (pSer87) antibody
XIAP 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated

anti-X-Linked Inhibitor of Apoptosis (XIAP) (C-Term) antibody
KO Validated XIAP 适用: 人 WB, IF, IHC (p), ICC 宿主: 兔 Polyclonal unconjugated

anti-X-Linked Inhibitor of Apoptosis (XIAP) (AA 201-330) antibody
XIAP 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC (p), FACS, IF (cc), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated

anti-X-Linked Inhibitor of Apoptosis (XIAP) (AA 1-497) antibody
XIAP 适用: 人 WB, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated

anti-X-Linked Inhibitor of Apoptosis (XIAP) (AA 1-497) antibody
XIAP 适用: 人 WB, IF, IP 宿主: 兔 Polyclonal unconjugated

anti-X-Linked Inhibitor of Apoptosis (XIAP) (AA 1-497) antibody
XIAP 适用: 人 WB, IF, PLA 宿主: 兔 Polyclonal unconjugated

anti-X-Linked Inhibitor of Apoptosis (XIAP) (AA 51-150) antibody
XIAP 适用: 人 WB, ELISA, IF, PLA 宿主: 小鼠 Monoclonal 1F4 unconjugated

anti-X-Linked Inhibitor of Apoptosis (XIAP) (AA 1-268) antibody
XIAP 适用: 人 ELISA, FACS 宿主: 小鼠 Monoclonal 4C12G10 unconjugated

anti-X-Linked Inhibitor of Apoptosis (XIAP) (AA 1-30) antibody
XIAP 适用: 人, 小鼠 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated

anti-X-Linked Inhibitor of Apoptosis (XIAP) (AA 1-200) antibody
XIAP 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated

应用备注

Western blot, 0.25-0.5 μg/mL, Human, Mouse, Rat
1. Cummins, J. M., Kohli, M., Rago, C., Kinzler, K. W., Vogelstein, B., Bunz, F.X-linked inhibitor of apoptosis protein (XIAP) is a nonredundant modulator of tumor necrosis factor-related apoptosis-inducing ligand (TRAIL)-mediated apoptosis in human cancer cells.Cancer Res. 64: 3006-3008, 2004. 2. Deveraux, Q. L., Takahashi, R., Salvesen, G. S., Reed, J. C.X-linked IAP is a inhibitor of cell-death proteases.Nature 388: 300-304, 1997. 3. Kim, J., Park, J., Choi, S., Chi, S.-G., Mowbray, A. L., Jo, H., Park, H.X-linked inhibitor of apoptosis protein is an important regulator of vascular endothelial growth factor-dependent bovine aortic endothelial cell survival.Circ. Res. 102: 896-904, 2008.

限制

仅限研究用
状态

Lyophilized

溶解方式

Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

浓度

500 μg/mL

缓冲液

Each vial contains 4 mg Trehalose, 0.9 mg NaCl and 0.2 mg Na2HPO4.

储存条件

4 °C,-20 °C

储存方法

At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.
抗原

XIAP (X-Linked Inhibitor of Apoptosis (XIAP))

别名

XIAP

背景

Synonyms: T-cell surface glycoprotein CD5, Lymphocyte antigen T1/Leu-1, CD5, CD5, LEU1
Tissue Specificity: Brain, liver, placenta, lymphocytes and erythrocytes.
Background: XIAP, also known as IAP3 or BIRC4, is a protein that stops apoptotic cell death. It is mapped to chromosome Xq25. This gene encodes a protein that belongs to a family of apoptotic suppressor proteins. Members of this family share a conserved motif termed, baculovirus IAP repeat, which is necessary for their anti-apoptotic function. This protein functions through binding to tumor necrosis factor receptor-associated factors TRAF1 and TRAF2 and inhibits apoptosis induced by menadione, a potent inducer of free radicals, and interleukin 1-beta converting enzyme. This protein also inhibits at least two members of the caspase family of cell-death proteases, caspase-3 and caspase-7. Mutations in this gene are the cause of X-linked lymphoproliferative syndrome. Alternate splicing results in multiple transcript variants.

分子量

54 kDa

基因ID

331

UniProt

P98170

途径

Apoptosis, Caspase Cascade in Apoptosis, Transition Metal Ion Homeostasis

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