RHBDF2 抗体 (AA 145-529)
Quick Overview for RHBDF2 抗体 (AA 145-529) (ABIN7600069)
抗原
See all RHBDF2 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 145-529
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原理
- Anti-RHBDF2 Antibody Picoband®
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交叉反应 （详细）
- No cross-reactivity with other proteins.
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产品特性
- Anti-RHBDF2 Antibody Picoband® (ABIN7600069). Tested in ELISA, Flow Cytometry, WB applications. This antibody reacts with Human. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
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纯化方法
- Immunogen affinity purified.
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免疫原
- E.coli-derived human RHBDF2 recombinant protein (Position: H145-D529).
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亚型
- IgG
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anti-Rhomboid 5 Homolog 2 (RHBDF2) (AA 80-109), (N-Term) antibody
RHBDF2 适用: 人, 小鼠 WB, IHC (p) 宿主: 兔 Polyclonal RB32834 unconjugated
anti-Rhomboid 5 Homolog 2 (RHBDF2) (AA 1-200) antibodyRHBDF2 适用: 人 ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Rhomboid 5 Homolog 2 (RHBDF2) (AA 1-200) antibodyRHBDF2 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
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应用备注
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Western blot, 0.25-0.5 μg/mL, Human
Flow Cytometry (Fixed), 1-3 μg/1x106 cells, Human
ELISA, 0.1-0.5 μg/mL, -
1. Adrain, C., Zettl, M., Cristova, Y., Taylor, N., Freeman, M. Tumor necrosis factor signaling requires iRhom2 to promote trafficking and activation of TACE. Science 335: 225-228, 2012. 2. Blaydon, D. C., Etheridge, S. L., Risk, J. M., Hennies, H.-C., Gay, L. J., Carroll, R., Plagnol, V., McRonald, F. E., Stevens, H. P., Spurr, N. K., Bishop, D. T., Ellis, A., Jankowski, J., Field, J. K., Leigh, I. M., South, A. P., Kelsell, D. P. RHBDF2 mutations are associated with tylosis, a familial esophageal cancer syndrome. Am. J. Hum. Genet. 90: 340-346, 2012. 3. Brooke, M. A., Etheridge, S. L., Kaplan, N., Simpson, C., O'Toole, E. A., Ishida-Yamamoto, A., Marches, O., Getsios, S., Kelsell, D. P. iRHOM2-dependent regulation of ADAM17 in cutaneous disease and epidermal barrier function. Hum. Molec. Genet. 23: 4064-4076, 2014. -
限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.
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储存条件
- 4 °C,-20 °C
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储存方法
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At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.
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- RHBDF2 (Rhomboid 5 Homolog 2 (RHBDF2))
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别名
- RHBDF2
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背景
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Synonyms: Chromaffin granule amine transporter, Solute carrier family 18 member 1, Vesicular amine transporter 1, VAT1, SLC18A1, VAT1, VMAT1
Tissue Specificity: Highly expressed in chromaffin cells of the adrenal medulla (at protein level). Detected in peripheral sympathetic ganglia (at protein level). Found in some paracrine cells in stomach and duodenum (at protein level).
Background: Rhomboid family member 2 is a protein that in humans is encoded by the RHBDF2 gene. Predicted to enable protein transporter activity. Predicted to be involved in negative regulation of protein secretion and regulation of epidermal growth factor receptor signaling pathway. Located in plasma membrane. Implicated in palmoplantar keratoderma-esophageal carcinoma syndrome.
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分子量
- 97 kDa
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基因ID
- 79651
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途径
- Growth Factor Binding
抗原
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