TIMM8A/DDP 抗体 (AA 14-97)
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Quick Overview for TIMM8A/DDP 抗体 (AA 14-97) (ABIN7600039)
抗原
See all TIMM8A/DDP (TIMM8A) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 14-97
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原理
- Anti-TIMM8A/DDP Antibody
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交叉反应 （详细）
- No cross-reactivity with other proteins.
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产品特性
- Anti-TIMM8A/DDP Antibody (ABIN7600039). Tested in ELISA, IF, IHC, ICC, WB applications. This antibody reacts with Human, Monkey, Mouse, Rat. This is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications.
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纯化方法
- Immunogen affinity purified.
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免疫原
- E.coli-derived human TIMM8A/DDP recombinant protein (Position: A14-D97).
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亚型
- IgG
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anti-Translocase of Inner Mitochondrial Membrane 8A (TIMM8A) (AA 9-97) antibody
TIMM8A 适用: 人 ELISA, WB, IHC (p) 宿主: 小鼠 Monoclonal 2F11 unconjugated
anti-Translocase of Inner Mitochondrial Membrane 8A (TIMM8A) (AA 1-97) antibodyTIMM8A 适用: 人 WB, IF 宿主: 小鼠 Polyclonal unconjugated
anti-Translocase of Inner Mitochondrial Membrane 8A (TIMM8A) (AA 1-72) antibodyTIMM8A 适用: 人 ELISA, WB 宿主: 小鼠 Monoclonal 1A12 unconjugated
anti-Translocase of Inner Mitochondrial Membrane 8A (TIMM8A) (AA 1-97) antibodyTIMM8A 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Translocase of Inner Mitochondrial Membrane 8A (TIMM8A) antibodyTIMM8A 适用: 人, 小鼠, 大鼠 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
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应用备注
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Western blot, 0.25-0.5 μg/mL, Human, Mouse, Rat, Monkey
Immunohistochemistry (Paraffin-embedded Section), 2-5 μg/mL, Human, Rat
Immunocytochemistry/Immunofluorescence, 5 μg/mL, Human
ELISA, 0.1-0.5 μg/mL, -
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.01 mg Sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
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Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
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- TIMM8A/DDP (TIMM8A) (Translocase of Inner Mitochondrial Membrane 8A (TIMM8A))
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别名
- TIMM8A
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背景
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Synonyms: Cadherin-4, Retinal cadherin, R-CAD, R-cadherin, CDH4
Tissue Specificity: Expressed mainly in brain but also found in other tissues.
Background: Mitochondrial import inner membrane translocase subunit Tim8 A, also known as Deafness-dystonia peptide or protein is an enzyme that in humans is encoded by the TIMM8A gene. This translocase is involved in the import and insertion of hydrophobic membrane proteins from the cytoplasm into the mitochondrial inner membrane. The gene is mutated in Mohr-Tranebjaerg syndrome/Deafness Dystonia Syndrome (MTS/DDS) and it is postulated that MTS/DDS is a mitochondrial disease caused by a defective mitochondrial protein import system. Defects in this gene also cause Jensen syndrome, an X-linked disease with opticoacoustic nerve atrophy and muscle weakness. This protein, along with TIMM13, forms a 70 kDa heterohexamer. Alternative splicing results in multiple transcript variants encoding distinct isoforms.
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分子量
- 13-14 kDa
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基因ID
- 1678
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UniProt
- O60220
抗原
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