MCM6 抗体 (AA 14-821)
Quick Overview for MCM6 抗体 (AA 14-821) (ABIN7600037)
抗原
See all MCM6 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 14-821
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原理
- Anti-MCM6 Antibody Picoband® (monoclonal, 3F13C4)
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交叉反应 （详细）
- No cross-reactivity with other proteins.
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产品特性
- Anti-MCM6 Antibody Picoband® (monoclonal, 3F13C4) (ABIN7600037). Tested in Flow Cytometry, IF, IHC, ICC, WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
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纯化方法
- Immunogen affinity purified.
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免疫原
- E.coli-derived human MCM6 recombinant protein (Position: Q14-D821).
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亚型
- IgG1
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anti-Minichromosome Maintenance Complex Component 6 (MCM6) (AA 562-821) antibody
MCM6 适用: 人 WB, IF, IP 宿主: 兔 Polyclonal unconjugated
anti-Minichromosome Maintenance Complex Component 6 (MCM6) (AA 1-821) antibodyMCM6 适用: 人 WB, IF, IHC (p), PLA 宿主: 小鼠 Polyclonal unconjugated
anti-Minichromosome Maintenance Complex Component 6 (MCM6) (AA 228-368) antibodyMCM6 适用: 人 IHC, StM 宿主: 小鼠 Monoclonal MCM6-2999 unconjugated
anti-Minichromosome Maintenance Complex Component 6 (MCM6) (AA 1-821) antibodyMCM6 适用: 人 WB, ELISA, IF 宿主: 小鼠 Monoclonal 7D8 unconjugated
anti-Minichromosome Maintenance Complex Component 6 (MCM6) (AA 589-605), (Middle Region) antibodyMCM6 适用: 人, 小鼠, 大鼠 IHC, WB, IF, ICC, FACS, IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Minichromosome Maintenance Complex Component 6 (MCM6) (AA 562-821) antibodyMCM6 适用: 人 IHC, WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Minichromosome Maintenance Complex Component 6 (MCM6) antibodyMCM6 适用: 人, 小鼠, 大鼠 IHC, WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Minichromosome Maintenance Complex Component 6 (MCM6) (C-Term) antibodyMCM6 适用: 人, 小鼠, 大鼠, 犬, Cow, 豚鼠, 马, 兔 IHC, WB 宿主: 兔 Polyclonal unconjugated
anti-Minichromosome Maintenance Complex Component 6 (MCM6) antibodyMCM6 适用: 人, 小鼠, 大鼠 IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Minichromosome Maintenance Complex Component 6 (MCM6) (C-Term) antibodyMCM6 适用: 人, 犬, Cow, 豚鼠, 马, 兔 IHC, WB, IHC (p) 宿主: 兔 Polyclonal unconjugated
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应用备注
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Western blot, 0.25-0.5 μg/mL, Human, Mouse, Rat
Immunohistochemistry(Paraffin-embedded Section), 2-5 μg/mL, Human, Mouse, Rat
Immunocytochemistry/Immunofluorescence, 5 μg/mL, Human
Flow Cytometry (Fixed), 1-3 μg/1x106 cells, Human
1. Bersaglieri, T., Sabeti, P. C., Patterson, N., Vanderploeg, T., Schaffner, S. F., Drake, J. A., Rhodes, M., Reich, D. E., Hirschhorn, J. N. Genetic signatures of strong recent positive selection at the lactase gene. Am. J. Hum. Genet. 74: 1111-1120, 2004. 2. Coelho, M., Luiselli, D., Bertorelle, G., Lopes, A. I., Seixas, S., Destro-Bisol, G., Rocha, J. Microsatellite variation and evolution of human lactase persistence. Hum. Genet. 117: 329-339, 2005. 3. Enattah, N. S., Sahi, T., Savilahti, E., Terwilliger, J. D., Peltonen, L., Jarvela, I. Identification of a variant associated with adult-type hypolactasia. Nature Genet. 30: 233-237, 2002. -
限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl and 0.2 mg Na2HPO4.
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储存条件
- 4 °C,-20 °C
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储存方法
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At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.
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- MCM6 (Minichromosome Maintenance Complex Component 6 (MCM6))
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别名
- MCM6
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背景
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Synonyms: Histone-binding protein RBBP4, Chromatin assembly factor 1 subunit C, CAF-1 subunit C, Chromatin assembly factor I p48 subunit, CAF-I 48 kDa subunit, CAF-I p48, Nucleosome-remodeling factor subunit RBAP48, Retinoblastoma-binding protein 4, RBBP-4, Retinoblastoma-binding protein p48, RBBP4, RBAP48
Background: MCM6(Minichromosome maintenance, s. pombe, homolog of, 6) is a protein that in humans is encoded by the MCM6 gene. MCM6 is one of the highly conserved mini-chromosome maintenance proteins (MCM) that are essential for the initiation of eukaryotic genome replication. The MCM genes were originally identified in yeast defective in minichromosome maintenance and have since been shown to play roles in the progression of the cell cycle, many are cell division control genes. The MCM6 gene is mapped on 2q21.3. Mcm 6 has recently been shown to interact strongly Cdt1 at defined residues, by mutating these target residues Wei et al. observed lack of Cdt1 recruitment of Mcm2-7 to the pre-RC. An approximately 200-kb region surrounding the C/T(-13910) polymorphism in MCM6 intron 13 functioned as an enhancer of the lactase gene promoter in intestinal cell culture.
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分子量
- 105 kDa
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基因ID
- 4175
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UniProt
- Q14566
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途径
- DNA Damage Repair, Mitotic G1-G1/S Phases, DNA Replication, Synthesis of DNA
抗原
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