PARP10 抗体 (AA 14-251)
Quick Overview for PARP10 抗体 (AA 14-251) (ABIN7600013)
抗原
See all PARP10 抗体适用
宿主
克隆类型
标记
应用范围
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                                            抗原表位
- AA 14-251
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                                            原理
- Anti-PARP10 Antibody Picoband®
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                                            交叉反应 (详细)
- No cross reactivity with other proteins.
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                                            产品特性
- Anti-PARP10 Antibody Picoband® (ABIN7600013). Tested in ELISA, WB, Flow Cytometry applications. This antibody reacts with Human. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
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                                            纯化方法
- Immunogen affinity purified.
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                                            免疫原
- E.coli-derived human PARP10 recombinant protein (Position: E14-E251). Human PARP10 shares 76.5% amino acid (aa) sequence identity with mouse PARP10.
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                                            亚型
- IgG
 
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                                            应用备注
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                        Western blot, 0.25-0.5 μg/mL, Human
 Flow Cytometry (Fixed), 1-3 μg/1x106 cells, Human
 ELISA, 0.1-0.5 μg/mL, -
 1. Kleine, H., Poreba, E., Lesniewicz, K., Hassa, P. O., Hottiger, M. O., Litchfield, D. W., Shilton, B. H., Luscher, B. Substrate-assisted catalysis by PARP10 limits its activity to mono-ADP-ribosylation. Molec. Cell 32: 57-69, 2008. 2. Lesniewicz, K., Luscher-Firzlaff, J., Poreba, E., Fuchs, P., Walsemann, G., Wiche, G., Luscher, B. Overlap of the gene encoding the novel poly(ADP-ribose) polymerase Parp10 with the plectin 1 gene and common use of exon sequences. Genomics 86: 38-46, 2005. 3. Yu, M., Schreek, S., Cerni, C., Schamberger, C., Lesniewicz, K., Poreba, E., Vervoorts, J., Walsemann, G., Grotzinger, J., Kremmer, E., Mehraein, Y., Mertsching, J., Kraft, R., Austen, M., Luscher-Firzlaff, J., Luscher, B. PARP-10, a novel Myc-interacting protein with poly(ADP-ribose) polymerase activity, inhibits transformation. Oncogene 24: 1982-1993, 2005.
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                                            限制
- 仅限研究用
 
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                                            状态
- Lyophilized
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                                            溶解方式
- Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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                                            浓度
- 500 μg/mL
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                                            缓冲液
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.
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                                            储存条件
- 4 °C,-20 °C
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                                            储存方法
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                        At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. 
 It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.
 
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    - PARP10 (Poly (ADP-Ribose) Polymerase Family, Member 10 (PARP10))
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                                            别名
- PARP10
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                                            背景
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                        Synonyms: 70 kDa ribosomal protein S6 kinase 1 antibody, KS6B1_HUMAN antibody, p70 alpha antibody, P70 beta 1 antibody, p70 ribosomal S6 kinase alpha antibody, p70 ribosomal S6 kinase beta 1 antibody, p70 S6 kinase alpha antibody, P70 S6 Kinase antibody, p70 S6 kinase alpha 1 antibody, p70 S6 kinase alpha 2 antibody, p70 S6K antibody, p70 S6K-alpha antibody, p70 S6KA antibody, p70(S6K) alpha antibody, p70(S6K)-alpha antibody, p70-alpha antibody, p70-S6K 1 antibody, p70-S6K antibody, P70S6K antibody, P70S6K1 antibody, p70S6Kb antibody, PS6K antibody, Ribosomal protein S6 kinase 70 kDa polypeptide 1 antibody, Ribosomal protein S6 kinase beta 1 antibody, Ribosomal protein S6 kinase beta-1 antibody, Ribosomal protein S6 kinase I antibody, RPS6KB1 antibody, S6K antibody, S6K-beta-1 antibody, S6K1 antibody, Serine/threonine kinase 14 alpha antibody, Serine/threonine-protein kinase 14A antibody, STK14A antibody Tissue Specificity: Expressed in all tissues. Background: Poly [ADP-ribose] polymerase 10 is an enzyme that in humans is encoded by the PARP10 gene. Poly(ADP-ribose) polymerases (PARPs), such as PARP10, regulate gene transcription by altering chromatin organization by adding ADP-ribose to histones. PARPs can also function as transcriptional cofactors. 
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                                            分子量
- 140 kDa
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                                            基因ID
- 84875
 抗原
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