RNF111 抗体 (AA 134-994)
Quick Overview for RNF111 抗体 (AA 134-994) (ABIN7599978)
抗原
See all RNF111 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 134-994
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原理
- Anti-RNF111 Antibody Picoband®
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产品特性
- Anti-R Antibody Picoband® (ABIN7599978). Tested in WB, IHC, ICC/IF, Flow Cytometry, ELISA applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
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纯化方法
- Immunogen affinity purified.
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免疫原
- E.coli-derived human RNF111 recombinant protein (Position: F134-S994).
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anti-Ring Finger Protein 111 (RNF111) (AA 1-108) antibody
RNF111 适用: 人 WB, ELISA, IF, RNAi 宿主: 小鼠 Monoclonal 1C4 unconjugated
anti-Ring Finger Protein 111 (RNF111) (AA 1-985) antibodyRNF111 适用: 人 WB, IHC (p) 宿主: 小鼠 Polyclonal unconjugated
anti-Ring Finger Protein 111 (RNF111) antibodyRNF111 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Ring Finger Protein 111 (RNF111) (AA 1-985) antibodyRNF111 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Ring Finger Protein 111 (RNF111) (C-Term) antibodyRNF111 适用: 人, 小鼠, 大鼠 WB, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated
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应用备注
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Western blot, 0.25-0.5 μg/mL, Mouse
Immunohistochemistry, 2-5 μg/mL, Mouse, Rat
Immunocytochemistry/Immunofluorescence, 5 μg/mL, Human
Flow Cytometry (Fixed), 1-3 μg/1x106 cells, Human
ELISA, 0.1-0.5 μg/mL, -
1. Episkopou, V., Arkell, R., Timmons, P. M., Walsh, J. J., Andrew, R. L., Swan, D. Induction of the mammalian node requires Arkadia function in the extraembryonic lineages. Nature 410: 825-830, 2001. 2. Niederlander, C., Walsh, J. J., Episkopou, V., Jones, C. M. Arkadia enhances nodal-related signalling to induce mesendoderm. Nature 410: 830-834, 2001. -
限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.
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储存条件
- 4 °C,-20 °C
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储存方法
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At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.
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- RNF111 (Ring Finger Protein 111 (RNF111))
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别名
- RNF111
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背景
- E3 ubiquitin-protein ligase Arkadia is an enzyme that in humans is encoded by the RNF111 gene. The protein encoded by this gene is a nuclear RING-domain containing E3 ubiquitin ligase. This protein interacts with the transforming growth factor (TGF) -beta/NODAL signaling pathway by promoting the ubiquitination and proteosomal degradation of negative regulators, like SMAD proteins, and thereby enhances TGF-beta target-gene transcription. As a modulator of the nodal signaling cascade, this gene plays a critical role in the induction of mesoderm during embryonic development. Alternative splicing of this gene results in multiple transcript variants encoding distinct isoforms.
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分子量
- 109 kDa
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基因ID
- 54778
抗原
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