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AGLU 抗体 (AA 131-2697)

AGLU 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, FACS 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN7599961
发货至: 中国
  • 抗原 See all AGLU 抗体
    AGLU (alpha-Glucosidase (AGLU))
    抗原表位
    • 1
    • 1
    • 1
    • 1
    AA 131-2697
    适用
    人, 小鼠, 大鼠
    宿主
    • 8
    • 3
    克隆类型
    • 8
    • 3
    多克隆
    标记
    • 8
    • 3
    This AGLU antibody is un-conjugated
    应用范围
    • 11
    • 4
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Flow Cytometry (FACS)
    原理
    Anti-MGAM Antibody Picoband®
    交叉反应 (详细)
    No cross-reactivity with other proteins.
    产品特性
    Anti-MGAM Antibody Picoband® (ABIN7599961). Tested in ELISA, IHC, WB, Flow Cytometry applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
    纯化方法
    Immunogen affinity purified.
    免疫原
    E.coli-derived human MGAM recombinant protein (Position: Y131-I2697).
    亚型
    IgG
    Top Product
    Discover our top product AGLU Primary Antibody
  • 应用备注
    Western blot, 0.25-0.5 μg/mL, Mouse, Rat
    Immunohistochemistry(Paraffin-embedded Section), 2-5 μg/mL, Mouse, Rat
    Flow Cytometry (Fixed), 1-3 μg /1x106 cells, Human
    ELISA, 0.1-0.5 μg/mL, -
    1. Naim, H. Y., Sterchi, E. E., Lentze, M. J. Structure, biosynthesis, and glycosylation of human small intestinal maltase-glucoamylase. J. Biol. Chem. 263: 19709-19717, 1988. 2. Nichols, B. L., Avery, S., Sen, P., Swallow, D. M., Hahn, D., Sterchi, E. The maltase-glucoamylase gene: common ancestry to sucrase-isomaltase with complementary starch digestion activities. Proc. Nat. Acad. Sci. 100: 1432-1437, 2003. 3. Nichols, B. L., Eldering, J., Avery, S., Hahn, D., Quaroni, A., Sterchi, E. Human small intestinal maltase-glucoamylase cDNA cloning: homology to sucrase-isomaltase. J. Biol. Chem. 273: 3076-3081, 1998.
    限制
    仅限研究用
  • 状态
    Lyophilized
    溶解方式
    Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
    浓度
    500 μg/mL
    缓冲液
    Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.
    储存条件
    4 °C,-20 °C
    储存方法
    At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
    It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.
  • 抗原
    AGLU (alpha-Glucosidase (AGLU))
    别名
    MGAM (AGLU 产品)
    背景

    Synonyms: Mesoderm posterior protein 1, Class C basic helix-loop-helix protein 5, bHLHc5, MESP1, BHLHC5

    Tissue Specificity: Highly expressed in brain and weakly in heart, small intestine and uterus. Isoform 1A is mostly expressed in granular cell and molecular layer. Isoform 1B is mostly expressed in Purkinje cells. Isoform 1E is predominantly expressed in peripheral tissues as kidney, lung, trachea, colon, small intestine, stomach, bone marrow, thymus and mammary gland. .

    Background: Maltase-glucoamylase, intestinal is an enzyme that in humans is encoded by the MGAM gene. This gene encodes maltase-glucoamylase, which is a brush border membrane enzyme that plays a role in the final steps of digestion of starch. The protein has two catalytic sites identical to those of sucrase-isomaltase, but the proteins are only 59 % homologous. Both are members of glycosyl hydrolase family 31, which has a variety of substrate specificities.

    分子量
    240 kDa
    基因ID
    8972
    UniProt
    O43451
    途径
    Cellular Glucan Metabolic Process
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