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ORC2 抗体 (AA 130-493)

The 兔 多克隆 anti-ORC2 antibody is suitable to detect ORC2 in samples from 人, 小鼠 和 大鼠. It has been validated for WB, ELISA, IHC, FACS, IF 和 ICC.
产品编号 ABIN7599954
发货至: 中国
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Quick Overview for ORC2 抗体 (AA 130-493) (ABIN7599954)

抗原

See all ORC2 抗体
ORC2 (Origin Recognition Complex Subunit 2 (ORC2))

适用

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人, 小鼠, 大鼠

宿主

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  • 1

克隆类型

  • 51
  • 6
多克隆

标记

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This ORC2 antibody is un-conjugated

应用范围

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Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Flow Cytometry (FACS), Immunofluorescence (IF), Immunocytochemistry (ICC)
  • 抗原表位

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    AA 130-493

    原理

    Anti-ORC2 Antibody

    交叉反应 (详细)

    No cross reactivity with other proteins.

    预测反应

    Human ORC2 shares 80.2%,79.4% amino acid (aa) sequence identity with mouse,rat ORC2,respectively.

    产品特性

    Anti-ORC2 Antibody. Tested in WB, IHC, ICC/IF, Flow Cytometry, ELISA applications. This antibody reacts with Human, Mouse, Rat.

    纯化方法

    Immunogen affinity purified.

    免疫原

    E.coli-derived human ORC2 recombinant protein (Position: E130-R493). Human ORC2 shares 80.2% and 79.4% amino acid (aa) sequence identity with mouse and rat ORC2, respectively.

    亚型

    IgG
  • 应用备注

    Western blot, 0.1-0.25 μg/mL, Human, Mouse, Rat Immunohistochemistry (Paraffin-embedded Section), 2-5 μg/mL, Human Immunocytochemistry/Immunofluorescence, 5 μg/mL, Human Flow Cytometry (Fixed), 1-3 μg/1x106 cells, Human ELISA, 0.1-0.5 μg/mL, -

    限制

    仅限研究用
  • 状态

    Lyophilized

    溶解方式

    Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

    浓度

    500 μg/mL

    缓冲液

    Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

    储存条件

    4 °C,-20 °C

    储存方法

    At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
    It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.

    有效期

    12 months
  • 抗原

    ORC2 (Origin Recognition Complex Subunit 2 (ORC2))

    别名

    ORC2

    背景

    Background: Origin recognition complex subunit 2 is a protein that is encoded by the ORC2 (ORC2L) gene in humans. The origin recognition complex (ORC) is a highly conserved six subunits protein complex essential for the initiation of the DNA replication in eukaryotic cells. Studies in yeast demonstrated that ORC binds specifically to origins of replication and serves as a platform for the assembly of additional initiation factors such as Cdc6 and Mcm proteins. The protein encoded by this gene is a subunit of the ORC complex. This protein forms a core complex with ORC3, -4, and -5. It also interacts with CDC45 and MCM10, which are proteins known to be important for the initiation of DNA replication. This protein has been demonstrated to specifically associate with the origin of replication of Epstein-Barr virus in human cells, and is thought to be required for DNA replication from viral origin of replication. Alternatively spliced transcript variants have been found, one of which is a nonsense-mediated mRNA decay candidate.

    Gene Full Name: origin recognition complex subunit 2

    分子量

    74 kDa

    基因ID

    4999

    UniProt

    Q13416
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