RYR2 抗体 (AA 1293-1423)
Quick Overview for RYR2 抗体 (AA 1293-1423) (ABIN7599921)
抗原
See all RYR2 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 1293-1423
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原理
- Anti-RYR2 Antibody Picoband®
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交叉反应 （详细）
- No cross-reactivity with other proteins.
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产品特性
- Anti-RYR2 Antibody Picoband® (ABIN7599921). Tested in ELISA, IHC, WB applications. This antibody reacts with Human. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
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纯化方法
- Immunogen affinity purified.
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免疫原
- E.coli-derived human RYR2 recombinant protein (Position: Q1293-T1423).
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亚型
- IgG
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anti-Ryanodine Receptor 2 (Cardiac) (RYR2) (AA 901-1192) antibody
RYR2 适用: 人 ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Ryanodine Receptor 2 (Cardiac) (RYR2) (AA 4850-4950) antibodyRYR2 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-Ryanodine Receptor 2 (Cardiac) (RYR2) (pSer2808) antibodyRYR2 适用: 人, 小鼠, 大鼠, 兔 IHC, WB, IF, IC 宿主: 兔 Polyclonal unconjugated
anti-Ryanodine Receptor 2 (Cardiac) (RYR2) (AA 1489-1502), (Intracellular) antibodyRYR2 适用: 人 IHC, WB, IF, IC 宿主: 兔 Polyclonal unconjugated
anti-Ryanodine Receptor 2 (Cardiac) (RYR2) antibodyRYR2 适用: 人, 小鼠, 大鼠 ELISA, WB, IF, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Ryanodine Receptor 2 (Cardiac) (RYR2) (Tyr1018) antibodyRYR2 适用: 人, 小鼠, 大鼠 ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Ryanodine Receptor 2 (Cardiac) (RYR2) (Tyr1018) antibodyRYR2 适用: 人, 小鼠, 大鼠 ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
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应用备注
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Western blot, 0.25-0.5 μg/mL, Human
Immunohistochemistry(Paraffin-embedded Section), 2-5 μg/mL, Human
ELISA, 0.1-0.5 μg/mL, -
1. Benkusky, N. A., Farrell, E. F., Valdivia, H. H. Ryanodine receptor channelopathies. Biochem. Biophys. Res. Commun. 322: 1280-1285, 2004. 2. Bhuiyan, Z. A., van den Berg, M. P., van Tintelen, J. P., Bink-Boelkens, M. T. E., Wiesfeld, A. C. P., Alders, M., Postma, A. V., van Langen, I., Mannens, M. M. A. M., Wilde, A. A. M. Expanding spectrum of human RYR2-related disease: new electrocardiographic, structural, and genetic features. Circulation 116: 1569-1576, 2007. 3. George, C. H., Higgs, G. V., Lai, F. A. Ryanodine receptor mutations associated with stress-induced ventricular tachycardia mediate increased calcium release in stimulated cardiomyocytes. Circ. Res. 93: 531-540, 2003. -
限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.
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储存条件
- 4 °C,-20 °C
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储存方法
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At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.
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- RYR2 (Ryanodine Receptor 2 (Cardiac) (RYR2))
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别名
- RYR2
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背景
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Synonyms: B-lymphocyte antigen CD19, Differentiation antigen CD19, CD19, Cd19
Background: Ryanodine receptor 2 (RYR2) is a protein found primarily in cardiac muscle. In humans, it is encoded by the RYR2 gene. This gene encodes a ryanodine receptor found in cardiac muscle sarcoplasmic reticulum. The encoded protein is one of the components of a calcium channel, composed of a tetramer of the ryanodine receptor proteins and a tetramer of FK506 binding protein 1B proteins, that supplies calcium to cardiac muscle. Mutations in this gene are associated with stress-induced polymorphic ventricular tachycardia and arrhythmogenic right ventricular dysplasia.
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分子量
- 564 kDa
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基因ID
- 6262
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UniProt
- Q92736
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途径
- Myometrial Relaxation and Contraction
抗原
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